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Time's Up

Merry Youle of the Small Things Considered blog has a new post up that looks at the phage-encoded holin timer and its function in a lytic infection.

"Holins are the smallest known biological timers. Timers, not clocks. Timers tick along, then go off after the specified interval. These small, ... Read More

El podcast del microbio Nº203: Antiguos eucariotas no marinos (earliest non-marine eukaryotes)



























El podcast del Microbio Nº203 is dedicated to Earth’s earliest non-marine eukaryotes, a discovery published in Nature journ... Read More

Museum pelts help date the koala retrovirus

The genomes of most higher organisms contain sequences from retroviral genomes called endogenous retroviruses (ERVs). These are DNA copies of retroviral RNAs that are integrated into the germ line DNA of the host, and passed from parent to offspring. In most species the infections that lead to g... Read More

El Podcast del microbio Nº 193 Con un poco de azúcar (A spoonful of sugar)



























El podcast del Microbio Nº193 describes the mBio 2010 paper by Huang et al. about the use of β-Glucan Particles to stimulat... Read More

TWiV 347: Rose rosette and squirrel roulette

Hosts: Vincent RacanielloAlan Dove, and Rich Condit


Vincent, Alan, and Rich discu... Read More

A Guide to Swine Flu (SciAm)

As swine influenza reaches the U.S., a guide to what you need to know and what happens next. Plus, a look at pandemics past... Read More

BacterioFiles 202 - Controlling Coliform Computers

This episode: Programming bacteria to sense and keep genomic records of environmental inputs!


(15.9 MB, 17.4 minutes)


Show notes: 
Read More

Compiling a list of reporters who cover #microbiology stories well; suggestions wanted

I am attempting to compile a list of reporters who do a good job covering microbiology related topics. I have compiled a partial list and am soliciting additional suggestions. Read More

TWiV 195 Letters

[we began be re-reading part of Deena's email from TWiV 193]


Ben writes:


Hello TWIV Crew,


I must first ap... Read More

TWiV 237: Paleovirology with Michael Emerman

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Hosts: Vincent Racaniello and Rich Condit Read More

Use of a Class 1 Safety Cabinet (video)

This video shows you how a Class 1 microbiological safety cabinet works. Read More

BacterioFiles 188 - Rat Residents Relieve Resin Roughness

This episode: Gut bacteria in Mojave desert woodrats help them detoxify and eat toxic creosote bushes!


(10 MB, 10.8 minutes)


Show notes: 
News item/ Read More

TWiV 77

Wladimir writes:


In regard to your question as to cases of known alteration of host behavior by virus that increases the rate of contact among hosts (Twiv 70), the most dramatic example is given by rabies. This extraordinary virus can convert a neurologically and behaviorally... Read More

Evolution of a DNA Sequence Over Time

One of the basic requirements of evolution is variation in a population upon which selection can act. One of the sources of variation is mutation in DNA. These changes may or may not be reflected in the ensuing amino acid sequence of a protein. This exercise explores the additive effects of m... Read More

TWiV 285: Hokies go viral

Vincent meets up with XJ Meng and Sarah McDonald at Virginia Tech in Blacksburg to talk about their work on viruses of swine and rotaviruses.


Host: Vincent Racaniello


Guests: Read More

Development of an HIV-1 Specific Microbicide Using Caulobacter crescentus

A recent paper published in PLoS One looks at the strategy of manipulating surface proteins on the aquatic bacterium, Caulobacter crescentus, to prevent HIV infection.

Abstract:

The development of alternative strategies to prevent HIV infection is a global public health priority. Initial e... Read More

Common Sense Advice for People Concerned About H1N1 (Swine Flu)

The New York Times has published a nice FAQ ,if you will, about H1N1 and what the general public should keep in mind in terms of worry, protection and symptoms. The article also talks about what public health response is feasible and should be expected. Read More

Spread of koala retrovirus in Australia

The Koala retrovirus (KoRV) continues to spread within Australia, according to results of a new analysis of a larger sample size from a wider geographical range than was previously studied. Read More

TWiV 269: Herpesvirus stops a nuclear attack

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Hosts: Vincent Racaniello, Dickson Despommier Read More

An Ebolavirus vaccine in Africa

An Ebolavirus vaccine has shown promising results in a clinical trial in Guinea. This vaccine has been in development since 2004 and was made possible by advances in basic virology of the past 40 years. Read More
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