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The Excitement of Clinical Microbiology

Clinical microbiologists uncover new and important pathogens, perform the role of sentinels to alert of possible upcoming epidemics, provide statistical and clinical information regarding the pathogens currently on the scene, and spur demands on research to create novel diagnostic tools. In fact... Read More

TWiV 276: Ramblers go viral

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

 Host: Vincent Racaniello


Guests: Read More

Dissection of the Burkholderia intracellular life cycle using a photothermal nanoblade

Using genetic dissection and photothermal nanoblade delivery, a recent paper published in PNAS by Jeff F. Miller, MD., Chair, Microbiology, Immunology, & Molecular Genetics, UCLA, and others, presents data that suggest that the primary means for intercellular spread of Burkholderia pseudomallei ... Read More

TWiV 227: Lacks security and bad poultry

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.


Hosts: Vincent Racaniello, Rich Condit, Read More

Lab Stuff I Wish I Could Use In My Kitchen

Do you ever take a look at what you’re doing in the lab and think, “Wow, this would really come in handy at home?” Here are a few of the things I use in the lab that I would love to have in my kitchen:

1. Stir plates and stir bars would be incredibly useful for cooking those dishes that need ... Read More

ASM's State of the Society 2012 Address by Dr. David Hooper

On Monday, June 18, 2012, then ASM President Dr. David Hooper gave the annual State of the Society Address to attendees at the 2012 ASM General Meeting in San Francisco, California, outlining the achievements of the Society over the past year. Click below to watch the archived video of this eve... Read More

A Microbiology Curriculum for K through 12 Grades

Bact to school time is on the horizon and I am sure many teachers, educators and professors are looking for supplemental course material or new ideas.

A quick search on the web resulted in this comprehensive Microbiology curriculum for K-12 that was presented at the 1997 Annual Meeting of th... Read More

SBTM12 - Sequence-Based Typing Methods for Microorganisms / Hands-on Bioinformatics Training Course - PORTUGAL

Applications are OPEN!
Deadline Sept 10th Course dates Sept 25th - 28th 2012

A highly intereactive course where participants will learn a lot about sequence-based typing methods. GTPB courses are designed to give maximum transfer of skills and user independence. Course fee = Euro 320. Lo... Read More

BacterioFiles 226 - Deep Dwellers Diversify

This episode: Archaea living in the deep ocean (and their viruses) have clever ways to maintain diversity and adaptability!


(10.3 MB, 11.25 minutes)


Show notes: 
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TWiM 60 Letters

Kelly writes:


I’m reeling from this episode!! The symbiosis, the web of life, the energies, chemicals, organisms of
evolutionary progression shaping our world naturally and by human intervention with unknown consequences, then you all tie it to the brain microbio... Read More

TWiP 49 Letters

Jim writes:


Professors, you've discussed this idea before, but I thought you'd enjoy this nice summary from Nature:

http://www.nature.com/nature/journal/v491/n7423/... Read More

TWiP 57 letters

Anne writes:


I found TWIP just a week ago and feel I've found a home. I'm a pharmacist, usually on the night shift, and stay excited all night listening to you. Parasites have always been my hobby. In fact, I recently divorced one. His life cycle is unique. I get oddl... Read More

BacterioFiles 204 - Animalcules Assist Agave Amino Accumulation

This episode: Bacteria living in plants seem to be contributing to plants' nutrition, possibly reducing the need for fertilizer!


(17.5 MB, 19.15 minutes)


Show notes: 
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TWiP 74 letters


voxsciurorum writes:


Dear water-based life forms:


It is 24 degrees in Overland Park, Kansas and I am looking at a slide labeled "Giardia lamblia", part of a museum exhibit on water and human (over) use of water.


I see a greenish lump. I don't know... Read More

Airway Microbiota and Pathogen Abundance in Age-Stratified Cystic Fibrosis Patients

Abstract - Bacterial communities in the airways of cystic fibrosis (CF) patients are, as in other ecological niches, influenced by autogenic and allogenic factors. However, our understanding of microbial colonization in younger versus older CF airways and the association with pulmonary function ... Read More

The Arctic fresh water virome

Although we now understand that viruses are the most abundant organisms on Earth, there are gaps in our knowledge about their distribution in different environments. Results of a new study reveal the diversity and distribution of viruses in Arctic fresh waters. Read More

TWiM 110 Letters

Trudy writes:


I'm sorry, I may have missed something, but the mechanism behind an effective vaccine is still unclear to me, since infection with F. tularensis does not confer protection. How would a vaccine work?


Katy Bosio replies:


In... Read More

Herpes simplex: Host Viral interactions database

This is a database of Herpes simplex (HSV-1) host/viral interactions hosted at WikiGenes. It provides a global snapshot of what the virus does in different compartments at all stages of the viral life-cycle from entry to exit. The database is interactive, and any researcher can edit the page or ... Read More

BacterioFiles 225 - Implanting Internal Invader Immunity

This episode: Don't have immunity? Create your own! Scientists engineer cells to destroy their HIV infections using the bacterial immune system!


(14.5 MB, 15.8 minutes)


Show notes: 
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Time's Up

Merry Youle of the Small Things Considered blog has a new post up that looks at the phage-encoded holin timer and its function in a lytic infection.

"Holins are the smallest known biological timers. Timers, not clocks. Timers tick along, then go off after the specified interval. These small, ... Read More
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