Vincent, Dickson, and Daniel solve last week's case study, present a new one, and reveal how secreted proteins from a helminth prevent diabetes in mice.
The lethality of avian influenza H5N1 infections in humans has been a matter of extensive debate. The >50% case fatality rate established by WHO is high, but the lethality of the virus might be lower if there are many infections accompanied by mild or no disease. One way to answer this question ... Read More
Tom talks with Vincent about viral central nervous system infections of global importance, Ebola virus, and running the fastest marathon dressed as a doctor.
Anna Skalka of Fox Chase Cancer Center in Philadelphia, Pa., discusses research into the ages of various virus families with Jeffrey Fox of Microbe magazine Read More
Maryn McKenna summarizes what we know about the murder of six people working as polio vaccinators who were targeted in three separate coordinated attacks in Pakistan. This comes in the wake of the CIA ruse in 2011 who used an immunization campaign to find Osama Bin Laden. Read More
How do you persuade philanthropists to pay $1 million for every pathogenic human virus you discover? Anjali Nayar talks to 'virus hunter' Nathan Wolfe in Cameroon to find out.
Every day, more than 100 patients line up for treatment outside the bare cement walls of a rural health clinic in the... Read More
This parasite interacts with many host proteins and modifies the expression of many more genes creating an interactome with almost 3000 links. In addition it exchanges substrates and metabolites with the host, modifying many biochemical parameters. T.Gondii disrupts multiple signalling network... Read More
The virus that is causing alarm among global public health authorities after it killed a man in Jeddah, Saudi Arabia earlier this year and is now linked to two other cases of disease is a novel type of coronavirus most closely related to viruses found in bats, according to a genetic analysis to ... Read More
Hi Vincent and Dickson,
I was listening to the new episode of TWiP (episode 52) and one of your listeners wrote in asking about tree parasites. While plant parasite is not my main field of research, I have written about one such pa... Read More
Professors, you've discussed this idea before, but I thought you'd enjoy this nice summary from Nature:
GEMINA is a web-based system to identify infectious pathogens and their representative genomic sequences through selection of associated epidemiology metadata. Gemina supports the development of DNA signature-based assays for the detection of pathogens or sets of pathogen through the Insignia Si... Read More
Viruses exist for one purpose only: to reproduce. To do that, they have to take over the reproductive machinery of suitable host cells.
Upon landing on an appropriate host cell, a virus gets its genetic material inside the cell either by tricking the host cell to pull it inside, like ... Read More