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The Great Epidemic - American Chestnut Blight

Merry Youle of Small Things Considered has a new post about the history of American chestnut blight and the scientific efforts to restock North America with these stately giants through the introduction of biological control agents or with more traditional plant breeding techniques.

Click so... Read More

April 2011 Microbe Feature article--BioCyc: Microbial Genomes and Cellular Networks

BioCyc: Microbial Genomes and Cellular Networks

by Peter D. Karp, Ingrid M. Keseler, Tomer Altman, Ron Caspi, Carol A. Fulcher, Pallavi Subhraveti, Anamika Kothari, Markus
Krummenacker, Mario Latendresse, Tom Lee, Suzanne M. Paley, Alexander G. Shearer, and Miles Trupp

The BioCyc system h... Read More

TWiP 69 letters


Richard writes:


Hi Vincent and Dickson,


I enjoy TWIP, and often recommend it to my students. I'm a parasitologist, primarily a Leishmaniac, but I have learnt a lot from TWIP. I find it both more educational and entertaining than Car Talk.


The disc... Read More

TWiV 252: Who read the last email?



Hosts: Vincent Racaniello, Dickson Despommier, Read More

New Non-Profit Directly Links Donors to Researchers; Seeks Submissions from Scientists in Need of Project Funding

St. Petersburg, Fla. – (Sept. 22, 2010) – Scientists and researchers seeking additional funding sources for projects that will enhance their research goals now have an alternative resource for the money they need to propel their projects forward: the general public. SciFlies.org, a new non-prof... Read More

TWiV 223: EEEV and the serpent



Hosts: Vincent Racaniello, Read More

Motility mechanism of malaria pathogens explained

How do one-celled parasites move from the salivary gland of a mosquito through a person's skin into red blood cells? What molecular mechanisms form the basis for this very important movement of the protozoa? A team of researchers headed by Dr. Friedrich Frischknecht, head of a research group at ... Read More

BacterioFiles 158 - Partners Provide Protein

This episode: Different bacteria working together can thrive better than when working alone!


(9.9 MB, 10.75 minutes)


Show notes: 
News item/ Read More

Cell Organization and Cell Motility (Part 1) by Julie Theriot

This lecture covers the biochemical basis of actin-based motility (focusing on the pathogen Listeria as a model system for this process), the biophysical mechanism of polymerization-based force generation, and an evolutionary perspective of cell shape in prokaryotes and eukaryotes. The first par... Read More

BacterioFiles Micro Edition 131 - Stacking Sucker Symbionts

This episode: Some insects have bacterial symbionts with super-small genomes inside their cells, and some of these symbionts have their own internal bacterial symbionts!


{joomp3_ext} Read More

New Coronavirus Related to Viruses From Bats

The virus that is causing alarm among global public health authorities after it killed a man in Jeddah, Saudi Arabia earlier this year and is now linked to two other cases of disease is a novel type of coronavirus most closely related to viruses found in bats, according to a genetic analysis to ... Read More

Happy Nerdy Holidays

I recently have come across a blog written by a biological anthropologist who is currently a stay at home mother to her little girl. A favorite hobby of hers is baking and her blog chronicles her culinary adventures, which much to my delight includes science themed baked goods like cookies and ... Read More

TWiM 65 Letters

Alexandra writes:


Dear TWIM-ers,


When I began listening to TWIV almost a year ago, I had just switched majors from philosophy to biology. I am now writing to you good people at TWIM at the end of my first undergraduate summer research gig, where I have had qui... Read More

The D225G change in 2009 H1N1 influenza virus

Last year a mutation in the HA gene of the 2009 H1N1 influenza virus was identified in isolates from patients with severe disease. At the time I concluded that the emergence of this change was not a concern. Recently the Norwegian Institute of Public Health reported that the mutation, which caus... Read More

TWiV 262: Wrong form, right professor

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.


Host: Vincent Racaniello


Guest: Read More

TWiV 226: Taking the viral A train with Terry Dermody



Hosts: Vincent Racaniello, Dickson Despommier, and Read More

TWiP 52 Letters

Jason writes:


Hi Drs. Despommier and Racaniello,


This week you wondered why the immune-activating receptor for Toxoplasma gondii, TLR11, is present in mice but not in humans. You noted that it looks like there's no selective pressure keeping it around in us an... Read More

Toxoplasmosis: A T.Gondii Host-pathogen interactome

This parasite interacts with many host proteins and modifies the expression of many more genes creating an interactome with almost 3000 links. In addition it exchanges substrates and metabolites with the host, modifying many biochemical parameters. T.Gondii disrupts multiple signalling network... Read More

BacterioFiles Micro Edition 38 - Competitor Curbs Cavities

This episode: Bacteria may help prevent cavities!




Read More

Download Poster (2003)


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