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BacterioFiles Micro Edition 147 - Clostridium Conquers Colleagues

This episode: Non-pathogenic Clostridium difficile strains can protect hamsters against their disease-causing bacterial siblings!


(7 MB, 7.5 minutes)


When hamsters were colonized with toxin-free strains of C. difficile, they were better able to resist infection b... Read More

TWiV 252: Who read the last email?

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Hosts: Vincent Racaniello, Dickson Despommier, Read More

TWiV 246: Pandora, pandemics, and privacy

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Hosts: Vincent Racaniello, Alan Dove, Read More

Interview with Tom Shenk about mBio, ASM's new open access journal

Tom Shenk is not only ASM’s Publications Board Chairman and a Princeton Professor, he’s also an instigator and a mastermind (in the well-intentioned and insightful senses of the words). After all, he was one of the original forces behind starting up mBio and his ideas and work continue to drive ... Read More

TWiV 291: Ft. Collins abuzz with virologists

Vincent, Rich, and Kathy and their guests Clodagh and Ron recorded this episode at the 33rd annual meeting of the American Society for Virology at Colorado State University in Ft. Collins, Colorado.


Hosts: ... Read More

TWiM 58 Letters

Daniel writes:


Dear Vincent and his fellow TWIMsters,

Hello, my name is Daniel, I am a first year graduate student at Michigan State. I would like to thank you all for making a great podcast. I recently caught up to the most current episodes by having my o... Read More

Don’t Panic—Ebola Isn’t Heading For You

An outbreak of Ebola hemorrhagic fever that began in early July 2012 has involved at least 36 individuals and 16 deaths. So far the disease has been confined to a rural region west of Kampala, the capital of Uganda. The subject of Richard Preston’s scary The Hot Zone, Ebola virus is newsworthy b... Read More

TWiV 308: The Running Mad Professor

Tom talks with Vincent about viral central nervous system infections of global importance, Ebola virus, and running the fastest marathon dressed as a doctor.


Host: Vincent Racaniello Read More

Prof. Racaniello's Viral Vaccines and the Principles of Immunization (Lecture)

Below is a lecture by Vincent Racaniello, Professor of Microbiology at Columbia University Medical Center and host of the popular This Week in Virology podcast, he presented on viral vaccines for the Immunology course at the Morningside Heights campus of Columbia University. Racaniello uses poli... Read More

Viral bioinformatics: Dotplot

Dotplots are an extremely useful way of visualizing comparisons of small and large DNA sequences (as well as protein sequences), providing insight into the degree of similarity, deletions, insertions and direct and indirect repeats. In a dotplot, each nucleotide, or small window of nucleotides, ... Read More

Of Terms in Biology: Colloids

Colloid may not be a common term in biology these days, but in the early 20th century, colloids were believed to hold the key to the secrets of life. So what is a colloid? According to the Encyclopaedia Britannica it is any substance consisting of particles substantially larger than atoms or ord... Read More

Magic in Solution: An Introduction and Brief History of PCR

If you missed the opportunity to hear Carl Wittwer talk about the history of PCR and his invention of the LightCycler, the video is now available on line.

The polymerase chain reaction (PCR) has become a fundamental tool in molecular research and clinical testing. Our presenter, Carl Witter, ... Read More

Video Presentations from Princeton's 2009 Spring Biosecurity Seminar Lectures

Here's a collection of presentations from Princeton's 2009 Spring Biosecurity Seminar Lectures. Presentations include:


Feb. 20 - George Hughes Senior Advisor, Counterterrorism and Intelligence FDA Office of Criminal Investigations
Title: " Read More

TWiP 95 letters

Ruben writes:


Dear Day-Twippers,


I am a big fan of TWIP. You do so many things right, that a little problem in your TWiP94 broadcast is not a big deal. As you may already know all three drugs in the Nutman et al. study are small molecules, not monoclonals, the... Read More

TWiP 69 letters


Richard writes:


Hi Vincent and Dickson,


I enjoy TWIP, and often recommend it to my students. I'm a parasitologist, primarily a Leishmaniac, but I have learnt a lot from TWIP. I find it both more educational and entertaining than Car Talk.


The disc... Read More

TWiP 42 Letters

Jesse writes:

Dear Doctor's Racaniello and Despommier,


Huzzah! I have tracked down Dick's missing book on tropical medicine, or at least another copy of said book. While listening to TWIP #40, my ears perked up when Dick said he had lent a book to a student only to h... Read More

TWiV 262: Wrong form, right professor

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Host: Vincent Racaniello


Guest: Read More

TWiV 294: Smallpox and anthrax and flu, oh my!

The TWiV team reviews the discovery of old vials of smallpox virus at NIH, anthrax and influenza mishaps at CDC, the baby who was not cured of HIV, Cambridge Working Group, and sacking of NSABB members.


Hosts:  Read More

TWiV 361: Zombie viruses on the loose

Hosts: Vincent RacanielloDickson DespommierAlan Dove, and  Read More

BacterioFiles Special - ASM2015

Here's my summary of ASM2015, an exciting weekend full of science.


(11.5 MB, 12.5 minutes)


Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.


Download Episode<... Read More

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