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Getting Started with MicrobeWorld

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TWiM #134: Lipids that live forever

Design of a synchronously lysing bacterium for delivery of anti-tumor molecules in mice, and hopanoids, the lipids that live forever, brought to you by the four Microbies of TWiM.


Hosts: Vincent Racaniello, Elio Schaechter,... Read More

Lab Hacks: Lab equipment from the hardware store

While almost every lab has a small toolbox with some screwdrivers, pliers, and such, here are some tools that may not have obvious utility at the bench, but could make your life easier. Jode Plank, a Postdoctoral Fellow studying DNA repair at the University of California at Davis shares some of ... Read More

Craig Venter announces synthetic life

This TED video captures Caig Venter's official announcement that his team created the first fully functioning, reproducing cell controlled by synthetic DNA. He explains how they did it and why the achievement marks the beginning of a new era for science. Read More

The Leopard and the Mouse: A Microbiologist's Take

The Small Things Considered blog has a post by Fred Neidhardt, F.G. Novy Distinguished University Professor, Emeritus, Department of Microbiology and Immunology, University of Michigan Medical School at Ann Arbor, that looks at two photos snapped by 19-year-old Casey Gutteridge at the Santago Ra... Read More

TWiV 386: The dolphins did it

Hosts: Vincent RacanielloRich Condit, and  Read More

BacterioFiles Micro Edition 53 - Bacteria Beta-oxidate Butanol Biofuel

This episode: Reversing a metabolic pathway is very effective!


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Do... Read More

TWiV 379: A mouse divided

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

Quick reference: Determining DNA Concentration and Purity

The most comprehensive way to evaluate DNA concentration and purity is to use both UV spectrophotometeric measurements and agarose gel eletrophoresis. This quick reference guide gives an overview of the information that can be derived from both.

This article is a clear and concise guide to th... Read More

Host-Pathogen Interaction and Human Disease (Part 1) by Stanley Falkow, Ph.D.

Stanley Falkow, Professor Microbiology and Immunology; Geographic Medicine; Infectious Diseases, Stanford University School of Medicine, presents a lecture on host-pathogen interaction.

"Ninety percent of the cells humans carry are microbes. Only a few of the bacteria we encounter are pathoge... Read More

MdlM117: Chagas, una infección olvidada...., por los países industrializados con Michael Levy

Hoy tenemos la suerte de contar con la compañía de Michael Z. Levy, Catedrático Asistente de Epidemiología en el Departamento de Bioestadística y Epidemiología de la Universidad de Pennsylvania, EE.UU.


Michael ha sido un incansable trabajador en el area de control/eliminación del vect... Read More

Repair DNA

Developing tricks and tools to keep their enzymes in order is one way thermophiles survive. They also use techniques to keep their DNA from falling apart under intense heat. Like proteins, the parts of the long, spiral ladder-shaped DNA molecule start to unravel and break apart under high hea... Read More

BacterioFiles Micro Edition 44 - Mosquito Microbes Mitigate Malaria

This episode: Bacteria fight malaria in the bellies of mosquitoes!


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Read More

TWiM 58 Letters

Daniel writes:


Dear Vincent and his fellow TWIMsters,

Hello, my name is Daniel, I am a first year graduate student at Michigan State. I would like to thank you all for making a great podcast. I recently caught up to the most current episodes by having my o... Read More

MMP #10: Examining the gut microbiota of American Indians of Cheyenne and Arapaho ancestry.

Host: Jeff Fox with special guests, Cecil M. Lewis, Jr. and Krithivasan Sankaranarayanan.


Lewis and Krithivasan Sankaranarayanan—“Krithi”-- both fro... Read More

BacterioFiles Micro Edition 22 - Shocking Shewanella

This episode: Bacteria form electric nanowires!


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Read More

Zinc inhibits rhinovirus replication - profvrr does an experiment

I was given a package of zinc lozenges when I contracted a cold a few weeks ago. That got me interested in the effect of zinc on rhinovirus replication. As a consequence I began a series of experiments to understand the mechanism of inhibition of viral replication by this metal. It's unusual tha... Read More

Did van Leeuwenhoek actually observe yeast cells in 1680?

Nanne Nanninga, Emeritus Professor of Molecular Cytology, Swammerdam Institute for Life Sciences, University of Amsterdam, The Netherlands, authors a guest post on Small Things Considered that questions whether van Leeuwenhoek actually observed yeast cells in 1680.

"It is common knowledge tha... Read More

TWiP 114: Plant potions perturb Plasmodium

The TWiP troika solve the case of the Female from the Bronx, and reveal how feeding on different plants affects mosquito capacity to transmit malaria.


Hosts: Vincent Racaniello Read More

TWiP 68 letters


Tim writes:


I listened to the latest TWIP this morning. Dickson mentioned the herbicide atrazine but thought it was a fungicide. It is actually a herbicide in the photosynthesis inhibitor class. Another bit of trivia about ag chemicals is that old chemicals like ... Read More

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