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Viruses of protozoan parasites may exacerbate human disease

Many protozoan parasites (Trichomonas, Leishmania, Giardia, Plasmodium, Entamoeba, Nagleria, Eimeria, Cryptosporidium) are infected with viruses. These viruses do not infect vertebrates, but their double-stranded RNA genomes are sensed by the innate immune system, leading to inflammatory complic... Read More

Inhibition of XMRV by a weapon of mass deamination

All mammalian genomes contain genes encoding Apobec proteins. Several members of this protein family (the name stands for apolipoprotein B mRNA editing complex) are induced by interferon and are intrinsic antiretroviral proteins. Apobec proteins inhibit the replication of XMRV, a new human retro... Read More

Airway Microbiota and Pathogen Abundance in Age-Stratified Cystic Fibrosis Patients

Abstract - Bacterial communities in the airways of cystic fibrosis (CF) patients are, as in other ecological niches, influenced by autogenic and allogenic factors. However, our understanding of microbial colonization in younger versus older CF airways and the association with pulmonary function ... Read More

TWiV 264: We should do an all email show some day

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Hosts: Vincent Racaniello, Alan Dove Read More

Are two tails better than one? A look at the Acidianus two-tailed virus

Merry Youle of Small Things Considered fame has a new post on the site that looks at the Acidianus two-tailed virus.

Snippet:

"Why two tails? Why such long tails? The researchers note that ATV is the only virus of an acidophilic hyperthermophile known to lyse its host, albeit only under st... Read More

BacterioFiles 160 - Residents Regulate RNA Response

This episode: Gut microbe communities can help regulate the immune response to pathogens!


(9.5 MB, 10.3 minutes)


Show notes: 
News item/ Read More

TWiV 275: Virocentricity with Eugene Koonin

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 Hosts: Vincent Racaniello and Rich Condit Read More

Common Sense Advice for People Concerned About H1N1 (Swine Flu)

The New York Times has published a nice FAQ ,if you will, about H1N1 and what the general public should keep in mind in terms of worry, protection and symptoms. The article also talks about what public health response is feasible and should be expected. Read More

TWiV 77

Wladimir writes:


In regard to your question as to cases of known alteration of host behavior by virus that increases the rate of contact among hosts (Twiv 70), the most dramatic example is given by rabies. This extraordinary virus can convert a neurologically and behaviorally... Read More

TWiV 216: Processing VIRALGUUAACACCAGRNA

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Hosts: Vincent Racaniello, Alan Dove, Read More

TWiV 224: A wide receiver and a natural defense

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Hosts: Vincent Racaniello, Alan Dove, and Read More

Watch This Week in Virology Episode 300 Live from ASM HQ Aug 26 7 pm ET

This Week in Virology, the podcast about viruses, celebrates its 300th episode on Tuesday, August 26, 2014 with a live recording at the Washington, DC headquarters of the American Society for Microbiology. This special episode w... Read More

TWiV 249: An inordinate fondness for viruses

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Hosts: Vincent Racaniello, Dickson Despommier,  Read More

Everyday Roles

Some people think it would be great if scientists could wipe out all the microbial bugs! Should we do it, and why or why not?


We get a lot of requests to track down the nasty bugs that are making people sick. It's true that some microbes cause health problems such as strep throat, chi... Read More

Life at the Extreme

Many archaeans thrive in conditions that would kill other creatures: boiling water, super-salty pools, sulfur-spewing volcanic vents, acidic water and deep in Antarctic ice. These types of archaea are often labeled "extremophiles," meaning creatures that love extreme conditions.

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Peptidoglycan remodeling and conversion of an inner membrane into an outer membrane during sporulation

I just finished listening to the TWiM 35 on LPS in Vibrio (among other topics). Dr. Elio Schaechter mentioned a field in Microbiology that I think is of great interest to the scientific community and should definitely be covered in a podcast. The topic is: Outer Membrane Biogenesis in Gram-negat... Read More

Dissection of the Burkholderia intracellular life cycle using a photothermal nanoblade

Using genetic dissection and photothermal nanoblade delivery, a recent paper published in PNAS by Jeff F. Miller, MD., Chair, Microbiology, Immunology, & Molecular Genetics, UCLA, and others, presents data that suggest that the primary means for intercellular spread of Burkholderia pseudomallei ... Read More

From a food blender to real-time fluorescent imaging

Although Avery, MacLeod, and McCarty showed in 1944 that nucleic acid was both necessary and sufficient for the transfer of bacterial genetic traits, protein was still suspected to be a critical component of viral heredity. Alfred Hershey and Martha Chase showed that this hypothesis was incorrec... Read More

Jay Keasling -Engineering Microbes to Produce Fuels

Jay Keasling, CEO of the Joint BioEnergy Institute, delivers the opening keynote on March 24, 2010 at the 5th Annual DOE JGI User Meeting. Read More

TWiP 72 letters


Robin writes:


plethora (n.)


1540s, a medical word for "excess of body fluid," from Late Latin plethora, from Greek plethore "fullness," from plethein "be full" (see pleio-). Figurative meaning "too-muchness, overfullness in any respect" i... Read More

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