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DIY Science - Jason Bobe of DIYbio speaks on NPR

The "Do It Yourself" biology movement is growing among real scientists and citizen scientists in homegrown or garage-based labs around the U.S. As this NPR piece reports "they're studying things like DNA and E. coli bacteria in home laboratories. And for now, the industry is largely unregulated.... Read More

TWiV 212: Apocalypse TWiV 122112 212

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Hosts: Vincent Racaniello, Rich Condit Read More

TWiM 62 Letters

Robert writes:
In TWIM #60 @1:06:23 Michael Schmidt suggests that glucose for fermentation from biomass is a necessary step in production of fuel ethanol. Fuel ethanol and other low molecular weight compounds can also be produced by autotrophic anaerobic fermentation of ... Read More

TWiM #128: A moonlighting phage protein

A eukaryote without a mitochondrion, and using a phage enzyme to eliminate intracellular bacteria are two topics discussed by the TWiMers on this episode.


Image (right): An entry in the ASM Agar Art Contest which bears an uncanny resemblance to one of the TWiM hosts.


Host... Read More

Retroviral integration and the XMRV provirus

A strong argument that the novel human retrovirus XMRV is not a laboratory contaminant is the the finding that viral DNA is integrated in chromosomal DNA of prostate tumors. Why does this result constitute such strong proof of viral infection?

Establishment of an integrated copy of the viral ... Read More

TWiV 368: Infected, you will be

Hosts: Vincent RacanielloAlan DoveRich Condit Read More

TWiV 205: Genetic conflict with Harmit Malik

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Hosts: Vincent Racaniello and Harmit Malik


Vincent is joined b... Read More

TWiM #127: Subway Snowblowers and Men in Black

The TWiM team explores microbes in snowblower vents on the ocean floor, and cleavage of antibody molecules by a Mycoplasma protease.


Image (right): Photograph of the ‘Subway’ snowblower vent on the sea floor at Axial Seamount, Juan de Fuca Ridge. Visible are white ‘snow’ in the vent a... Read More

BacterioFiles Micro Edition 25 - Bdefining Bdellovibrio Bdivision

This episode: A study of the bacteria-hunting Bdellovibrio life cycle!


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Read More

BacterioFiles Micro Edition 33 - Playing Paramecium Pong

This episode: Video games with live microbes!


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Read More

TWiV 361: Zombie viruses on the loose

Hosts: Vincent RacanielloDickson DespommierAlan Dove, and  Read More

The human genome is composed of viral DNA II: Individual proteins contain multiple viral inserts

Individual proteins, and individual translated exons within these proteins, are composed of multiple internested viral protein fragments. This is illustrated for the translated exons of DISC1 , where the different viral contributions are colour coded for each virus or phage. Read More

TWiM 107 Letters

Jim writes:


Hi Vince,
For your interest in listening to physics, there is a podcast called The Titanium Physicists Podcast. They use a conversational format similar to what you use. They have a panel of experts and a guest who is not a physicist but who is accom... Read More

BacterioFiles Micro Edition 43 - Cells Survive Centrifuging

This episode: Microbes grow under hypergravity!


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Read More

BacterioFiles 247 - Animalcule Acetate Ameliorates Asthma

This episode: Feeding mice high-fiber diets reduces their risk of allergic airway disease, even across generations!


(12.1 MB, 13.2 minutes)


Show notes: 
Read More

TWiV 91 Letters

Darrick and Scott write:


Hello Professor Racaniello,


We are two graduate students from the University of Guelph in Canada studying oncogenic sheep betaretroviruses and we are big fans of the show. Part of the reason we like the show so much is that we can use ... Read More

Lab Hacks: Lab equipment from the hardware store

While almost every lab has a small toolbox with some screwdrivers, pliers, and such, here are some tools that may not have obvious utility at the bench, but could make your life easier. Jode Plank, a Postdoctoral Fellow studying DNA repair at the University of California at Davis shares some of ... Read More

TWiV 308: The Running Mad Professor

Tom talks with Vincent about viral central nervous system infections of global importance, Ebola virus, and running the fastest marathon dressed as a doctor.


Host: Vincent Racaniello Read More

BacterioFiles 218 - Parasitoids Pass Protective Prokaryotes

This episode: Parasitoid wasps spread helpful bacterial symbionts between their whitefly prey!


(10.9 MB, 11.9 minutes)


Show notes: 
Read More

Is circovirus DNA infectious?

The US Food and Drug Administration does not want Rotarix, the rotavirus vaccine, to be used because it contains porcine circovirus 1 DNA. If complete copies of the circovirus genome were present, would they constitute a potential threat to recipients? Put another way, is circovirus DNA infectio... Read More
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