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BacterioFiles 225 - Implanting Internal Invader Immunity

This episode: Don't have immunity? Create your own! Scientists engineer cells to destroy their HIV infections using the bacterial immune system!

(14.5 MB, 15.8 minutes)

Show notes: 
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TWiV 350: Viral gene therapy with Katherine High

Host: Vincent Racaniello

Guest: Katherine A. High

Vincent speaks with Katherine High about her... Read More

A collection of polioviruses

In midsummer 1986, five years after starting my poliovirus laboratory at Columbia University, I received a letter from Frederick L. Schaffer, a virologist at the University of California, Berkeley, asking if I would like to have his collection of poliovirus stocks. He was retiring and the sample... Read More

An Ebolavirus vaccine in Africa

An Ebolavirus vaccine has shown promising results in a clinical trial in Guinea. This vaccine has been in development since 2004 and was made possible by advances in basic virology of the past 40 years. Read More

BacterioFiles 224 - Super Small Cells

This episode: Scientists discover what seem to be ultra-small bacteria, possibly smaller than the theoretical minimum size!

(12.3 MB, 13.4 minutes)

Show notes: 
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TWiV 349: One ring to vaccinate them all

Hosts: Vincent RacanielloAlan Dove, and Rich ... Read More

Infections and more problems

Infections can come from a wide range of different ways such as shaking someone hand or touching something with a infection i like a hand towel and as some of you will know part of why in hospital the spread of infection so easy to happen people are together in hospital as such if infection s... Read More

TWiP 93 letters

Sandra writes:

Daniel: I was fascinated by your answer to the case from TWIP 91 - the life cycle of the southeast Asian worm (I won't even try to spell it.) Re early symptom coughing & wheezing: if the ED did a chest X-ray out of concern about the lungs, would the... Read More

TWiP 93: A fishy tale unfolds

 Vincent, Dickson, and Daniel solve their fishy tale, and present a new case study for your consumption.

Hosts: Vincent Racaniello Read More

Can You Protect Your Tummy From Traveler's Diarrhea?

It goes by many names: Delhi belly. Montezuma's revenge. The Aztec two-step. But doctors use one not-so-glamorous term: traveler's diarrhea. Read More

TWiM #109: Precision killing

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 109 Letters

Geoffrey writes:

Dear Doctors:

I just went to my semi-annual dental appointment and I thought of a potentially interesting oral health monitor - the plaque biofilm that they scrape off your teeth during the cleaning. Brush immediately before the cleaning ... Read More

A preliminary report on the contact-independent antagonism of Pseudogymnoascus destructans by Rhodococcus rhodochrous strain DAP96253

This article provides the preliminary results of a possible treatment/ Biological control agent for White Nose Syndrome (WNS) cause by Pseudogymnoascus destructans. It is estimated that over 5.5 of North American bats have died due to this deadly disease. Recently this method of treatment descri... Read More

BacterioFiles 223 - Fecal Fusions Forecast Fatness

This episode: Sampling microbial populations in sewage from cities could reveal differences in the human populations, such as prevalence of obesity!

(9.1 MB, 9.9 minutes)

Show notes: 
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Honoring the Memory of Another

The late Edward Leadbetter had a huge impact on my life as an academic, and a microbiologist. In this post, I try to give some appreciation to what he meant to me. Read More

TWiV 348: Chicken shift

Hosts: Vincent Racaniello and Rich Condit

Vincent and Rich discuss fruit fly viruses, one year without polio in Nigeria, and a permissive Mar... Read More

"Never Really Alone" with Ed Yong!

Each Fall, I teach a freshman writing class about symbioses and parasitism. I was very lucky to get some pretty famous people to "Skype" or "Google Hang Out" in to visit my class. Last Fall, one of my "tele-speakers" was the fabulous science writer and very funny fellow Ed Yong. The students ... Read More

Permissive vaccines and viral virulence

A permissive vaccine prevents disease in the immunized host, but does not block virus infection. Would a permissive vaccine lead to the emergence of more virulent viruses?

This hypothesis is based on the notion that viruses which kill their hosts too quickly are not efficiently transmitted, a... Read More

Francis Crick Portrait in Living Light!

This is as portrait of the late Francis Crick created by my wife Dr. Jennifer Quinn using "paint" of luminous bacteria. Photobacterium leignothi was grown in LB amended to 20g/l NaCl for a few hours until visible luminescence was detected visually. The liquid culture was painted onto amended L... Read More

New Powerful Sweet Antibiotic against Superbugs was Found

Scientists from the University of Queensland and a biotechnology company discovered a new class of antibiotics, which is a kind of synthetic sugar. And the new antibiotics can significantly decrease the drug resistance caused by bacteria, and kill them. These new antibiotics can be a powerful dr... Read More
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