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Viral gifts

If you are looking for the perfect present for that infectious person in your life, there are many microbe-themed possibilities. Here are some suggestions, from t-shirts, to watercolors, glass sculptures, and paper to wrap it in. Read More

TWiM #70: A paroxysmal cough

Hosts: Vincent RacanielloElio SchaechterMichael Schmidt and Read More

Mundo de los Microbios - Episodio 106 - Ricardo Santos

Aunque el género Mycobacterium es asociado a infecciones tales como la lepra y la tuberculosis, hay un gran número de especies que son por lo general no patogénicos o patógenos oportunistas. En el episodio de hoy tenemos al Dr. Ricardo Santos del Instituto Superior Técnico de Lisboa, Portugal... Read More

BacterioFiles Micro Edition 147 - Clostridium Conquers Colleagues

This episode: Non-pathogenic Clostridium difficile strains can protect hamsters against their disease-causing bacterial siblings!


(7 MB, 7.5 minutes)


When hamsters were colonized with toxin-free strains of C. difficile, they were better able to resist infection b... Read More

TWiV 263: Game of clones

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Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove Read More

Molecular mechanisms of resistance

The abilities of bacterial organisms to utilize the various strategies to resist antimicrobial compounds are all genetically encoded.

Intrinsic resistance is that type of resistance which is naturally coded and expressed by all (or almost all) strains of that particular bacterial species. An... Read More

Reduced glycopeptide and lipopeptide susceptibility in Staphylococcus aureus and the “seesaw effect”: Taking advantage of the back door left open?

Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More

Handling the cholera outbreak of 1854

This article discusses the famous pump handle that John Snow may or may not have had removed ... read the article to get the true story. From medical historian Peter Vinten-Johansen. Read More

BacterioFiles Micro Edition 146 - Engineered Escherichia Eliminates Enemies

This episode: Scientists engineered E. coli to seek and destroy pathogens!


(10 MB, 11 minutes)


A bacterium can sense pathogens in the body, swim toward them, and release a deadly biofilm-busting payload. This process is called pseudotaxis, and could be modified for many... Read More

TWiV 262: Wrong form, right professor

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Host: Vincent Racaniello


Guest: Read More

Remembering a Microbial Hero™: The Late, Great Abigail Salyers.

Here I remember a person who a great deal of influence on my views about microbiology in the classroom, and the laboratory: the late Abigail Salyers. RIP, Abigail. Read More

Some "Rules" for Academia and Research

In this blog post, I describe some "rules for academics" as well as my own "rules for research." I hope that readers find them useful and perhaps a bit humorous. Read More

BacterioFiles Micro Edition 145 - Clostridium Converts Cortisol

This episode: Gut bacteria may convert cortisol into important human hormones!


(6 MB, 6.5 minutes)


Note: Episode 144 is now available too. Sorry about that. Not sure what went wrong there, but it is regrettable.


A minor player in the gut, Clostridium scindens,... Read More

Antimicrobial Susceptibility Pattern and ESBL Production among Uropathogenic Escherichia coli Isolated from UTI Children in Pediatric Unit of a Hospital in Kerman, Iran

 


Emergence of antibiotic resistance and extended spectrum β- lactamase (ESBL) among uropathogens in the pediatric unit of hospitals created serious health care concern. This study deals with antimicrobial susceptibility and ESBL analysis of uropathogenic Escherichia coli isolate... Read More

TWiV 261: Giants among viruses

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Hosts: Vincent Racaniello and Jame... Read More

TWiM #69: Bacterial DNA in the human genome

Hosts: Vincent RacanielloElio SchaechterJo Handelsman and Read More

TWiM 69 Letters

Gian writes:


Beloved TWiMers,


Did you see this paper in PLoS Computational Biology? It's mind-blowing. U. Maryland researchers found evidence for Acinetobacter and Pseudomonas nucleic acid integrated into human chromosomes and mitochondria, po... Read More

BacterioFiles Micro Edition 144 - Copper Chelator Calms Quicksilver

This episode: Bacteria could reduce mercury's toxicity in their environment!


(6.5 MB, 7 minutes)


Methanotrophs (bacteria that use methane for their carbon and energy) secrete siderophore-like compounds that are usually used to chelate copper and make it more bioavailable, but ... Read More

Changing influenza virus neuraminidase into a receptor binding protein

The hemagglutinin (HA) and neuraminidase (NA) glycoproteins of the influenza virus particle serve distinct functions during infection. The HA binds sialic acid-containing cellular receptors and mediates fusion of the viral and cell membranes, while the NA removes sialic acids from glycoproteins.... Read More

TWiV 260: Badgers go viral

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Host: Vincent Racaniello


Guests: Read More

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