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Twenty-six lectures in virology

In the spring of each year I teach a virology course to undergraduates and masters students at Columbia University. I produce video recordings of all my lectures not only for students in the course, but for anyone else who is interested in learning about viruses.

You can find my virology lect... Read More

1 in 25 patients gets infection in hospital

When antibiotics first started being used in the 1940's they were considered a "miracle drug". It seemed that bacterial infections would no longer be a problem for the world. However, recently, one gene is making it seem as though the end of antibiotics is at hand. This gene is New Delhi metallo... Read More

TWiM #75: Pellicles on pickle jars

Hosts: Vincent RacanielloElio SchaechterMichael Schmidt and Read More

BacterioFiles 159 - Drastic Diet Develops Different Dwellers

This episode: Gut microbe communities can change rapidly to accommodate major diet changes!


(12.2 MB, 13.3 minutes)


Show notes: 
Read More

TWiV 277: My podcast Vinny

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Hosts: Glenn Rall, Ann Skalka, and  Read More

Click-Chemistry Labeling of Oligonucleotides and DNA - Lumiprobe - Protocol


Click chemistry is a versatile reaction that can be used for the synthesis of a variety of conjugates. Virtually any biomolecules can be involved, and labeling with small molecules, such as fluorescent dyes, biotin, and other groups can be readily achieved.

Click chemistry reaction takes pl... Read More

Interview of Dr. Tim Sandle

Q) Dr. Tim Sandle, the well known researcher, professor, author and science communicator. It is much interesting for me to take an interview of an eminent person who is well known for the communicating science. Starting from your early childhood life, how you used to take science as that time?
... Read More

HIV gets the zinc finger

Because all animal viruses initiate infection by binding to a receptor on the cell surface, this step has long been considered a prime target for antiviral therapy. Unfortunately, drugs that block virus attachment to cells have never shown much promise. Another approach, which is to ablate the r... Read More

TWiV 276: Ramblers go viral

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 Host: Vincent Racaniello


Guests: Susan Baker Read More

TWiM #74: It came from the Siberian permafrost

Hosts: Vincent RacanielloElio Schaechter, and Michael Schmidt


Vin... Read More

Attenuated influenza vaccine enhances bacterial colonization of mice

Infection with influenza virus is known to increase susceptibility to bacterial infections of the respiratory tract. In a mouse model of influenza, increased bacterial colonization was also observed after administration of an infectious, attenuated influenza virus vaccine. Primary influenza viru... Read More

Breathing New Life into DNA Microarrays

DNA microarrays are widely used in biological research and were once thought to be a very promising gene discovery tool. However, since the advent of next generation DNA sequencing, the popularity of DNA microarrays has steadily declined. Compared to the sequencing, microarray behavior is unce... Read More

BacterioFiles 158 - Partners Provide Protein

This episode: Different bacteria working together can thrive better than when working alone!


(9.9 MB, 10.75 minutes)


Show notes: 
News item/ Read More

TWiV 275: Virocentricity with Eugene Koonin

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 Hosts: Vincent Racaniello and Rich Condit Read More

TWiP 68 letters


Tim writes:


I listened to the latest TWIP this morning. Dickson mentioned the herbicide atrazine but thought it was a fungicide. It is actually a herbicide in the photosynthesis inhibitor class. Another bit of trivia about ag chemicals is that old chemicals like ... Read More

TWiP 68: Sex and the single trypanosome



Hosts: Vincent Racaniello Dickson Despommier, and Read More

Mundo de los Microbios - Episodio 107 - Delfina Urbina

Uno de los patógenos más importantes en América Latina y seguramente el mundo entero, el rotavirus, es discutido en este episodio de La Radio El Mundo de los Microbios. La Prof. Delfina Urbina, con una larga trayectoria en diferentes áreas de la Microbiología nos visita hoy. Fué Profesora Tit... Read More

Pithovirus: Bigger than Pandoravirus with a smaller genome

A new virus called Pithovirus sibericum has been isolated from 30,000 year old Siberian permafrost. It is the oldest DNA virus of eukaryotes ever isolated, showing that viruses can retain infectivity in nature for very long periods of time. Read More

BacterioFiles 157 - Azotobacter Assists Algae

This episode: Nitrogen-fixing bacteria could provide nitrogen to algae in biotech processes!


(7.4 MB, 8 minutes)


Show notes: 
Journal... Read More

TWiV 274: Data dump

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Hosts: Vincent Racaniello, Dickson Despommier, Read More

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