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TWiP 16: Giardia

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Vincent and Dickson review the life cycle and pathogenesis of the flagellated protozoan parasite Giardia lamblia.


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TWiM #29: Death and an iron-loaded spike

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Hosts: Vincent Racaniello and S... Read More

TWiM 34: Doing the DISCO with Emiliania

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Hosts: Vincent Racaniello, Read More

TWiM #11: Chickens, antibiotics, and asthma

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Hosts: Vincent Racaniello, Read More

TWiV 113: Alan Rein on XMRV


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Vincent, Alan, and Rich discuss the retrovirus XMRV with ret... Read More

BacterioFiles Micro Edition 71 - Bright Bacteria Brave Biting

This episode: Some ocean bacteria glow to attract those that eat them!



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TWiV 134: Meet Ralph, your cruise director

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Hosts: Vincent Racaniello, Rich Condit, Read More

TWiP 38 Letters

Carlos writes:


Dear Vincent Racaniello and Dickson Despommier


I am an avid listener of TWIP since its start, have been following TWIV for at least two years and, surprise, also follow TWIM.


My field is Computer Science, but I crave for... Read More

TWiV 181 Letters

Spencer writes:


I would like to propose the book:


Netter's Infectious Diseases, 1e as a lis... Read More

TWiV 194: Five postdocs in North America

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Hosts: Vincent Racaniello, Matthew Daugherty, Jondavid d... Read More

Understanding cell organization

Franklin M. Harold, Department of Microbiology, University of Washington has authored an interesting guest post on www.SmallThingsConsidered.us that examines the process of cell structural organization and assembly:

"Structural organization is one of the most conspicuous features of cells, a... Read More

BacterioFiles Micro Edition 23 - Dry Dry Desert Dwellers

This episode: Bacteria grow on quartz stones in the driest hot place on Earth!


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... Read More

Canine hepacivirus, a relative of hepatitis C virus

Contemporary human viruses most likely originated by cross-species transmission from non-human animals. Examples include HIV-1, which crossed from chimpanzees to humans, and SARS coronavirus, which originated in bats. Since the 1989 discovery of hepatitis C virus (classified as a hepacivirus in ... Read More

Detecting viral proteins in infected cells or tissues by immunostaining

Many virological techniques are based on the specificity of the antibody-antigen reaction. Examples in our virology toolbox include western blot analysis and ELISA. While very useful, these methods cannot be used to visualize viral proteins in infected cells or tissues. To do that we must turn t... Read More

New influenza A virus found in bats

Influenza A virus reservoirs in animals have provided novel genetic elements leading to the emergence of global pandemics in humans. Most influenza A viruses circulate in waterfowl, but those that infect mammalian hosts are thought to pose the greatest risk for zoonotic spread to humans and the ... Read More

TWiV 150: Contaminated

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Hosts: Vincent RacanielloR... Read More

The Rise of Community-Associated MRSA

This teleconference is sponsored by the American Society for Microbiology and will review the history and importance of methicillin-resistant Staphylococcus aureus (MRSA) with a primary focus on the emergence of community-associated MRSA (CA-MRSA). The phenotypic and molecular identification of ... Read More

New Elsevier Slogan: “It’s All about The Benjamins”

Rich Condit found an article highly critical of the original Wakefield study (claiming a link between MMR vaccine and autism) which was published in the same issue of Lancet. He asked the publisher, Elsevier, to open up the article to non-subscribers so he could recommend it as a pick of the wee... Read More

The Lazarus virus

There is an excellent question in the comments to “Are all virus particles infectious?“: if the particle-to-PFU ratio for a virus stock is 10,000:1, and I infect 1,000,000 cells with 10,000 particles, how many plaques would I expect to observe? Answering this question provides insight into the p... Read More

Norton Zinder, 1928-2012

Norton Zinder made two important discoveries in the field of virology. While a Ph.D. student with Joshua Lederberg at the University of Wisconsin-Madison he found that viruses of bacteria (bacteriophages) could move genes from one host to another, a process called transduction. Later in his own ... Read More
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