The Nobel Prize for Medicine this year went to Dr. Yoshinori Ohsumi of the Tokyo Institute for Technology for his work on autophagy, the process of digesting unneeded or damaged cellular components. This process plays a role in many central cellular activities, with applications ranging from gen... Read More
(Millbrook, NY) Machine learning can pinpoint rodent species that harbor diseases and geographic hotspots vulnerable to new parasites and pathogens. So reports a new study in the Proceedings of the National Academy of Sciences led by Barbara A. Han, a disease ecologist at the Cary Institute of E... Read More
The great folks at "The People Behind the Science" interviewed me over Skype in late July, and the interview has just been released as a podcast. I discuss my path through science, my thoughts on teaching, research at undergraduate institution, and how to motivate and inspire students to strive... Read More
If you are lucky enough to be still alive and working in 2050... How might the clinical microbiology laboratory have changed by that time? Nobody can accurately predict the future, but here are my personal thoughts... Read More
New research conducted at the University of Miami in Coral Gables, Florida and the National Cancer Institute, in Bethesda, Maryland demonstrate that a subset of bacteriophages, dubbed “superspreaders,” potentially play a major role in transmitting antimicrobial resistance. The research, describe... Read More
The general program for the 2015 American Society of Microbiology meeting in New Orleans is out, and registration is now open. The sessions look incredible, and I've listed them below as I imagine they might resonate with many of the readers of this blog. The bolded sessions look particularly in... Read More
Stable Isotope Labeled MS Peptide Standard
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Science writer Maryn McKenna interviews John Sever, MD, PhD, former chief of infectious diseases at the National Institutes of Health and current vice-chairman of Rotary’s International PolioPlus Committee, about the early days of the polio struggle and the introduction of the polio vaccine.
... Read More
In this ASM Virtual Lecture Dr. James McSharry, Professor Emeritus, Albany Medical College, describes the structure of the influenza viruses, types of human influenza viruses and their replication in cells, licensed influenza drugs, current influenza vaccines, and the future of influenza vacci... Read More
In this episode of Virus Watch, I show how to do my favorite assay in all of virology - the plaque assay.
Dear water-based life forms:
It is 24 degrees in Overland Park, Kansas and I am looking at a slide labeled "Giardia lamblia", part of a museum exhibit on water and human (over) use of water.
I see a greenish lump. I don't kno... Read More
How do bacterial proteins destined for export move from inside to outside the cell? As mBiosphere readers may know, there are a number of secretion systems that bacteria use to move materials from inside the cell to outside the cell. Some of these systems, such as the Sec secretion system, are c... Read More
Microbes are excellent at adapting to stressful situations, which is part of the reason antibiotic resistance is a problem today. Constant exposure to antimicrobials such as triclosan have selected for resistant strains, rendering the compound ineffective. This is why the FDA recently banned t... Read More
In an attempt to preserve and defend the good name of the salmon fished in his state, Senator Warren Magnuson (D-WA), introduced in 1969 a bill in the US Senate proposing to change the name of Salmonella to the more inoccuous sounding Sanella. In some circles it may seem comforting to th... Read More
DNA methylation is important for epigenetic research. Here the author introduced several basic method of DNA methylation detection. Good articles. Read More
Ribose Nucleic Acid, also named RNA, is the intermediary of DNA and protein. Compared with DNA, RNA has less molecular-weight but more classification.With the development of all kinds of research, scientists found that RNA plays an important role in the evolution of life. I hope this article can... Read More
Taxonomic profiling is a challenging first step when analyzing a metagenomic sample. This work presents a method that facilitates fine-scale characterization of the presence, abundance, and evolutionary relatedness of organisms present in a given sample but absent from the training database. We ... Read More
Something you need know about Viral Antigens
What are Viral Antigens? We can hear this word every time when the heavy flu spreads across the world such as SARS, Ebola and Bird Flu. Actually, a Viral Antigen can be regarded as a toxin and it is some substance which is produced by a virus. This k... Read More