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Cholesterol Oxidase

Recombinant Cholesterol Oxidase belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. This enzyme participates in bile acid biosynthesis.
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ASM Members Deliver a Landslide Endorsement for Governance Change - Part 2

In my previous posting (Part 1), I reflected on the historical change of the new ASM governance. Here I would like to highlight some key issues that I see facing ASM and its new governance structure. This is not a prescriptive list, but rather a list of goals or, if you prefer, a straw man for ... Read More

A “Polio Warrior” Recounts Decades of Struggle Toward Eradication

Science writer Maryn McKenna interviews John Sever, MD, PhD, former chief of infectious diseases at the National Institutes of Health and current vice-chairman of Rotary’s International PolioPlus Committee, about the early days of the polio struggle and the introduction of the polio vaccine.

... Read More

"What will change in Clinical Microbiology Laboratories by 2050?"

If you are lucky enough to be still alive and working in 2050... How might the clinical microbiology laboratory have changed by that time? Nobody can accurately predict the future, but here are my personal thoughts... Read More

Online definitions of

People increasingly get medical information online, so it's important for physicians to understand how antibiotic drugs are presented to the curious public. I've collected several definitions of "antibiotic" and "microorganism" to demonstrate how people might easily think colds and flu are treat... Read More

Influenza Viruses by James McSharry, PhD

In this ASM Virtual Lecture Dr. James McSharry, Professor Emeritus, Albany Medical College, describes the structure of the influenza viruses, types of human influenza viruses and their replication in cells, licensed influenza drugs, current influenza vaccines, and the future of influenza vacci... Read More

BacterioFiles 294 - Bacteria Benefit Bad Burns

This episode: Probiotic bacteria prevent deadly infections in mice with serious burns!


(6.3 MB, 6.92 minutes)


Show notes: 


Journal Paper:

Argenta A, Satish L, Gallo P, Liu F, Kathju S. 2016. Read More

S. mutants mutation increases fluoride resistance


Microbes are excellent at adapting to stressful situations, which is part of the reason antibiotic resistance is a problem today. Constant exposure to antimicrobials such as triclosan have selected for resistant strains, rendering the compound ineffective. This is why the FDA recently banned t... Read More

Evidence for the Biosynthesis of Bryostatins by the Bacterial Symbiont “Candidatus Endobugula sertula” of the BryozoanBugula neritina

I thought this area of bryostatin study might spark your interest. It has the potential to treat cancer and Alzheimer’s disease. Whether looking at the way the compound is formed in nature or the challenge of synthesizing the compound is fascinating.

https://www.google.com/search?q=bryozoan+B... Read More

Moleculo Facilitates Assembly and Binning from Soil

Soil microorganisms carry out key processes for life on our planet, including cycling of carbon and other nutrients and supporting growth of plants. However, there is poor molecular-level understanding of their functional roles in ecosystem stability and responses to environmental perturbations.... Read More

An Unseen Step to Diagnoses: Specimen Handling

Collecting, transporting, and storing patient specimens plays a major role in infection diagnoses. ASM provides a number of resources regarding best practices and the latest research regarding specimen collection! Read More

Virus Watch: Counting Viruses

In this episode of Virus Watch, I show how to do my favorite assay in all of virology - the plaque assay.

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Seeking understanding of the bacterial sec system

How do bacterial proteins destined for export move from inside to outside the cell? As mBiosphere readers may know, there are a number of secretion systems that bacteria use to move materials from inside the cell to outside the cell. Some of these systems, such as the Sec secretion system, are c... Read More

A protein platform for priming

The enzymes that make copies of the DNA or RNA genomes of viruses – nucleic acid polymerases – can be placed into two broad categories depending on whether or not they require a primer, a short piece of DNA or RNA, to get going. The structure of the primer-independent RNA polymerase of hepatitis... Read More

Forecasting future infectious disease outbreaks

(Millbrook, NY) Machine learning can pinpoint rodent species that harbor diseases and geographic hotspots vulnerable to new parasites and pathogens. So reports a new study in the Proceedings of the National Academy of Sciences led by Barbara A. Han, a disease ecologist at the Cary Institute of E... Read More

Tell Us Your Story about You and Your Proteins

We would like to know the experience when you work with your proteins (recombinant protein, native protein, lysate etc.), no matter it is success or failure. Did you get on well with the protein or still “fight” with it? Tell us your story. But, no, no, no, we don’t want to hear your presentatio... Read More

XPF cell line

The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5 incision made during nucleotide excision repair. This complex is a structure specific
contact us: contact@creative-biogene.com
Tel: 5166698109
Visit: http://www.creative-biogene.com/Human-XPF-Knockdown-Cell-L... Read More

History Lesson - The Day the US Senate Tried to Change the Name of Salmonella

In an attempt to preserve and defend the good name of the salmon fished in his state, Senator Warren Magnuson (D-WA), introduced in 1969 a bill in the US Senate pro­po­sing to change the name of Salmonella  to the more in­oc­cu­ous sounding Sanella. In some circles it may seem com­for­ting to th... Read More

Should you consider attending ASM 2015 this spring?

The general program for the 2015 American Society of Microbiology meeting in New Orleans is out, and registration is now open. The sessions look incredible, and I've listed them below as I imagine they might resonate with many of the readers of this blog. The bolded sessions look particularly in... Read More

MetaPalette: a k-mer Painting Approach for Metagenomic Taxonomic Profiling and Quantification of Novel Strain Variation

Taxonomic profiling is a challenging first step when analyzing a metagenomic sample. This work presents a method that facilitates fine-scale characterization of the presence, abundance, and evolutionary relatedness of organisms present in a given sample but absent from the training database. We ... Read More
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