The World Health Organization launched the first World Antibiotic Awareness week, and from November 16-22 2015 discussion centered on the emerging threat of antibiotic resistance. In this post, I will review the science behind antibiotic resistant-bacteria and how this phenomena is poised to imp... Read More
No matter the niche field a scientist pursues, there is one aspect of almost all career paths that scientists have in common: teaching. Whether lecturing a quorum of undergraduates about bacterial genetics, mentoring a research fellow as they learn the lab protocols, or presenting an invited lec... Read More
Virus populations do not consist of a single member with a defined nucleic acid sequence, but are dynamic distributions of nonidentical but related members called a quasispecies (illustrated at left). While next-generation sequencing methods have the capability of describing a quasispecies, the ... Read More
Last Fall, the great Dr. Margaret McFall-Ngai "virtually visited" my freshman writing class at the University of Puget Sound to discuss symbiosis and Microbial Supremacy with my new students. I had my students read some papers by Dr. McFall-Ngai (including the wonderful "Animals in a Microbial ... Read More
The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids.
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Sea stars are lovely marine invertebrates with a round central body connected to multiple radiating legs (photo credit). In the past year millions of sea stars in the west coast waters of North America have melted into piles of slime and ossicles. Sea star associated densovirus might be the caus... Read More
Referenced dataset of host/pathogen interactions for Borrelia burgdorferi: linked to Kegg pathway interactome analysis Read More
A major goal of viral oncotherapy – the use of viruses to destroy tumors – is to design viruses that kill tumor cells but not normal cells. Two adenoviruses provide perfect examples of how this specificity can be achieved.
Adenovirus CG0070, designed to treat bladder cancer, and adenovirus O... Read More
The Journal of Bacteriology is celebrating its centennial this year – one hundred years of valuable scientific discoveries! To illustrate the wide variety of noteworthy results published over the years, the journal is publishing a Classic Spotlight series, in which experts in the field highlight... Read More
For years, researchers have struggled to get a handle on Group B streptococcus (GBS), in the hopes of improving neonatal outcomes. GBS are a bacteria commonly found in the vagina, rectum, and urinary tract of women. In healthy women, the bacteria are commensal, simply living without causing dise... Read More
This episode: Spherical cyanobacterium Synechocystis acts like a tiny eyeball in sensing light, allowing cells to move closer to light sources!
(9.7 MB, 10.6 minutes)
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After the governors of New York and New Jersey decided that health workers who have returned from the Ebola virus outbreak in West Africa should be subject to a 21-day quarantine, two Nobel laureates entered the fray. Bruce Beutler feels that the quarantine is the right thing to do, while Peter ... Read More
So far in this series I’ve written a good deal about our work on Zika virus, but I have said little about the people who are doing the science.
My lab at Columbia University Medical Center is very small, consisting of three people—Amy Rosenfeld, Audrey Warren, and me. Let me tell you about ... Read More
Rhinovirus is the most frequent cause of the common cold, and the virus itself is quite common: there are over 160 types, classified into 3 species. The cell receptor has just been identified for the rhinovirus C species, which can cause more severe illness than members of the A or B species: it... Read More
Well you may ask what virus ?
and I tell you West Nile Virus ( but I want to change it to WNV ). Every year when mosquito season arrives it will bring a lot of diseases . one of them is the memory loss. you may ask how does memory loss concern WNV?
Thousands of people are liv... Read More
The 1918 influenza pandemic was particularly lethal, not only for the very young and the very old (as observed for typical influenza), but unexpectedly also for young adults, 20 to 40 years of age (pictured). It has been suggested that the increased lethality in young adults occurred because the... Read More
Six new cases of Heartland virus disease have been identified in residents of Missouri and Tennessee. The cause of this disease appears to be a member of the Phlebovirus genus in the Bunyaviridae family that was first identified in 2009 and appears to be transmitted by the Lone Star tick (Amblyo... Read More
Given the extent of the Ebola virus outbreak in West Africa, transport of an infected individual to the US was bound to happen. The case is an adult who had contact with an Ebola virus-infected woman in Liberia, then traveled to Dallas. He had no symptoms before arriving in the US and therefore ... Read More
BDP FL maleimide
BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy. BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar... Read More
In the second of two shows recorded at the University of North Carolina in Chapel Hill, Vincent meets up with faculty members to talk about how they got into science, their research on RNA viruses, and what they would be doing if they were not scientists.
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