Two vaccines against Zika virus developed at the University of Pittsburgh School of Medicine have successfully conveyed immunity from female mice to pups conceived weeks after the mother's vaccination.
When challenged with Zika virus within a week of their birth, both vaccines protected the p... Read More
I hope we have all had an opportunity over the past holiday weekend to give thanks for what we have—it is important to step back and reflect from time to time on the many benefits and advantages we have. It can help us realize what we have achieved, and the multitude of people and resources that... Read More
Infection control is a vital part of maintaining a safe healthcare facility, and the use of biocides and disinfectants to eliminate potential pathogens is an important part of infection control strategy. Pathogens can spread among patients via transfer to surfaces like doors, floors, and counter... Read More
When Antonio Gonzalez began doctoral studies in Rob Knight’s laboratory, then at University of Colorado, Boulder, the computer scientist quickly learned about microbes and their connection to human health. He soon found a connection to his wife’s health jumping out of the literature at him.
H... Read More
BDP FL maleimide
BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy. BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar... Read More
Genomes of non-defective viruses range in size from 2,400,000 bp of dsDNA (Pandoravirus salinus) to 1,759 bp of ssDNA (porcine circovirus). Are even smaller viral genomes possible? The subviral agents called viroids provide an answer to this question.
Viroids, the smallest known pathogens, ar... Read More
There are countless examples of plant, animal and bacterial viruses that cause severe symptoms of disease, sometimes with considerable socio-economic consequences. Viruses of fungi, otherwise known as ‘mycoviruses’, infect many medically and commercially important fungi, including the brewers an... Read More
Given the extent of the Ebola virus outbreak in West Africa, transport of an infected individual to the US was bound to happen. The case is an adult who had contact with an Ebola virus-infected woman in Liberia, then traveled to Dallas. He had no symptoms before arriving in the US and therefore ... Read More
Many microbes live in extreme environments, encountering conditions that are very hot, very cold, highly acidic, or very salty. The viruses that infect such microbes must also be able to retain infectivity in extreme conditions. How do they do it?
Clues come from the observations that the gen... Read More
Viruses can be broadly classified according to whether or not the particle is enveloped – surrounded by a membrane taken from the host cell – or naked. Some naked viruses apparently are more modest than we believed. Read More
Vincent Racaniello of the This Week in Virology podcast interviews David Baltimore, PhD, California Institute of Technology, about his career and professional experience in the field of virology. Baltimore received a 1975 Nobel laureate in Physiology or Medicine for work on the interaction betwe... Read More
Hurricane Matthew hit Haiti on October 4, 2016, and the southeast United States two days later, leaving tens of thousands without power, transportation, and in the worst cases, homes. Because of its extreme poverty, and its continuing recovery from previous natural disasters, Haiti is looking at... Read More
Good news for sustainable textiles of the future was announced in a recent Applied and Environmental Microbiology report that described the discovery of microbial polyesterase genes. The study described the discovery and characterization of new enzymes from microbial communities associated with ... Read More
In this blog post, I share the creative projects that my Biology 350 (Microbiology) micronauts created this semester. They range from video parodies, to prose poems, to short-short stories to sculptures and needlepoint. Enjoy! Read More
Follow the reconstruction and simulation of poliovirus using the BlueGene/Q supercomputer at the Victorian Life Sciences Computation Initiative. The poliovirus model is being used as a basis for understanding antiviral drugs, virus infection and helps us to learn how to model related viruses suc... Read More
Unknown fungi isolated from soil sample.I would like to have inputs from the Mycologist in the forum about this fungal colony,its identification,name,species and genus? Read More
Susceptibility break points are a dirty compromise between clinical, pharmacokinetic. and epidemiological break points. Because they are a necessary compromise, there will always be disagreement, and they can never be perfect. Is there a better way? Read More
If you are currently a microbiologist, chances are your introductory microbiology lab course syllabus hadn’t changed for decades. The course likely culminated in each student receiving an unknown bacterial sample, the identity of which was uncovered by applying techniques learned during the seme... Read More