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Dual virus-receptor duel

Viruses are obligate intracellular parasites: they must enter a cell to reproduce. To gain access to the cell interior, a virus must first bind to one or more specific receptor molecules on the cell surface. Cell receptors for viruses do not exist only to serve viruses: they also have cellular f... Read More

El podcast del microbio Nº 378. Llave Falsa (False Key)



























El podcast del microbio Nº 378 summarize an article published in Nature communications by Ribeiro-Viana R et al. on the use of Virus-like glycodendrinanoparticles to block viral infection. El podcast del microbio Nº 3... Read More

BDP FL maleimide - BODIPY analog - fluorescent labeling of proteins

BDP FL maleimide
http://www.lumiprobe.com/p/bodipy-fl-maleimide

BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy. BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar... Read More

Innocence by Viral Tagging - Finalist in Ocean 180 Video Challenge

Viruses are the most abundant biological entities on the planet with approximately 1030 in the world’s oceans at any time. As such, they play a central role in global nutrient cycling. Despite their ecological importance, little is known about how viruses interact with their hosts due to the dif... Read More

ASM GM 2014 - The Effect of Pancreatic Cancer on the Oral Microbiome

In the United States, approximately 40,000 people die every year due to pancreatic adenocarcinoma, making it the fourth leading cause of cancer related death. Patients diagno... Read More

Happy Microbial Valentines Day---In Words of Living Light!

In this short blog post, I "write" on Petri dishes with bioluminescent bacteria to create words and poems in "living light." I also write a haiku to quorum sensing in the same style! Read More

Zaire ebolavirus in West Africa

Dr. Tom Solomon is Director of the Institute for Infection and Global Health at the University of Liverpool. In this video he speaks with Vincent Racaniello about the 2014 outbreak of Zaire ebolavirus in West Africa. Dr. Solomon discusses why the epidemic has spread, how it might be curtailed, t... Read More

apple of my eye

I love to share my work,the simplicity in Happiness.I am sharing it here because i know my fellow microbiologist also admire this visual treats in their labs. http://adeebblog.blogspot.in/ Read More

How a microscopic team alters the course of carbon in the Atlantic ocean - Finalist in Ocean 180 Video Challenge

The Amazon river is the largest river in the world. It drains the entire Amazon rainforest, sending leftover nutrients, detritus, and minerals from the South American jungle out into the tropical Atlantic ocean. This runoff forms a freshwater plume, hundreds of miles across, that profoundly affe... Read More

A Whiff of Taxonomy – Archaeoglobus fulgidus

Pick an archaeon, any archaeon, and you will find it has a story to tell. Not all archaea are exotic but plenty of them are. These stalwarts live in environments we humans call extreme, where they carry out what to us seem extreme types of metabolic conversions. Most have come rather late into o... Read More

Rapid emergence and antigenic diversification of the norovirus 2012 Sydney variant in Denmark, October to December, 2012

The norovirus (NoV) season in Denmark in late 2012 was characterised by an increase in the number of NoV infections caused mainly by the 2012 Sydney variant, but also by the 2009 New Orleans variant. Analysis of approximately 85% of the capsid gene from 10 Sydney 2012 and 9 New Orleans 2009 isol... Read More

ASM GM 2014 - This Week in Virology #286: Boston TWiV Party

The American Society for Microbiology hosted a live podcast of This Week in Virology with Vincent Racaniello with co-host Alan Dove that includes guests Paul Duprex, Director of Cell and Tissue Imaging Core, Boston University, National Emerging Infectious Diseases Laboratories (NEIDL), and Ju... Read More

Here's What Would Really Happen If You Stopped Bathing

You've probably gone a few days without showering -- maybe a week. But let's say you don't bathe for days on end -- as in you use no soap, no water, no nothing.

What would happen?

Click "source" to find out. Read More

New Drugs May Come from Microbes in Our Guts

Plants and Microorganisms are the major sources of drugs till date. Most of these "natural products" come from a few genera of soil and marine bacteria that have long been known for their prolific chemistry. The classical process of discovering drugs from microorganisms have two drawbacks- it is... Read More

A protein platform for priming

The enzymes that make copies of the DNA or RNA genomes of viruses – nucleic acid polymerases – can be placed into two broad categories depending on whether or not they require a primer, a short piece of DNA or RNA, to get going. The structure of the primer-independent RNA polymerase of hepatitis... Read More

Reduced glycopeptide and lipopeptide susceptibility in Staphylococcus aureus and the “seesaw effect”: Taking advantage of the back door left open?

Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More

Blocking HIV infection with two soluble receptors

Because viruses must bind to cell surface molecules to initiate replication, the use of soluble receptors to block virus infection has long been an attractive therapeutic option. Soluble receptors have been developed that block infection with rhinoviruses and HIV-1, but these have not been licen... Read More

Molecular mechanisms of resistance

The abilities of bacterial organisms to utilize the various strategies to resist antimicrobial compounds are all genetically encoded.

Intrinsic resistance is that type of resistance which is naturally coded and expressed by all (or almost all) strains of that particular bacterial species. An... Read More

Ebolavirus will not become a respiratory pathogen

An otherwise balanced review of selected aspects of Ebolavirus transmission falls apart when the authors hypothesize that ‘Ebola viruses have the potential to be respiratory pathogens with primary respiratory spread.’

The idea that Ebolavirus might become transmitted by the respiratory route ... Read More

TWiV 330: A swinging gate

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

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