Viruses are obligate intracellular parasites: they must enter a cell to reproduce. To gain access to the cell interior, a virus must first bind to one or more specific receptor molecules on the cell surface. Cell receptors for viruses do not exist only to serve viruses: they also have cellular f... Read More
El podcast del microbio Nº 378 summarize an article published in Nature communications by Ribeiro-Viana R et al. on the use of Virus-like glycodendrinanoparticles to block viral infection. El podcast del microbio Nº 3... Read More
BDP FL maleimide
BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy. BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar... Read More
Viruses are the most abundant biological entities on the planet with approximately 1030 in the world’s oceans at any time. As such, they play a central role in global nutrient cycling. Despite their ecological importance, little is known about how viruses interact with their hosts due to the dif... Read More
In the United States, approximately 40,000 people die every year due to pancreatic adenocarcinoma, making it the fourth leading cause of cancer related death. Patients diagno... Read More
In this short blog post, I "write" on Petri dishes with bioluminescent bacteria to create words and poems in "living light." I also write a haiku to quorum sensing in the same style! Read More
Dr. Tom Solomon is Director of the Institute for Infection and Global Health at the University of Liverpool. In this video he speaks with Vincent Racaniello about the 2014 outbreak of Zaire ebolavirus in West Africa. Dr. Solomon discusses why the epidemic has spread, how it might be curtailed, t... Read More
I love to share my work,the simplicity in Happiness.I am sharing it here because i know my fellow microbiologist also admire this visual treats in their labs. http://adeebblog.blogspot.in/ Read More
The Amazon river is the largest river in the world. It drains the entire Amazon rainforest, sending leftover nutrients, detritus, and minerals from the South American jungle out into the tropical Atlantic ocean. This runoff forms a freshwater plume, hundreds of miles across, that profoundly affe... Read More
Pick an archaeon, any archaeon, and you will find it has a story to tell. Not all archaea are exotic but plenty of them are. These stalwarts live in environments we humans call extreme, where they carry out what to us seem extreme types of metabolic conversions. Most have come rather late into o... Read More
The norovirus (NoV) season in Denmark in late 2012 was characterised by an increase in the number of NoV infections caused mainly by the 2012 Sydney variant, but also by the 2009 New Orleans variant. Analysis of approximately 85% of the capsid gene from 10 Sydney 2012 and 9 New Orleans 2009 isol... Read More
The American Society for Microbiology hosted a live podcast of This Week in Virology with Vincent Racaniello with co-host Alan Dove that includes guests Paul Duprex, Director of Cell and Tissue Imaging Core, Boston University, National Emerging Infectious Diseases Laboratories (NEIDL), and Ju... Read More
You've probably gone a few days without showering -- maybe a week. But let's say you don't bathe for days on end -- as in you use no soap, no water, no nothing.
What would happen?
Click "source" to find out. Read More
Plants and Microorganisms are the major sources of drugs till date. Most of these "natural products" come from a few genera of soil and marine bacteria that have long been known for their prolific chemistry. The classical process of discovering drugs from microorganisms have two drawbacks- it is... Read More
The enzymes that make copies of the DNA or RNA genomes of viruses – nucleic acid polymerases – can be placed into two broad categories depending on whether or not they require a primer, a short piece of DNA or RNA, to get going. The structure of the primer-independent RNA polymerase of hepatitis... Read More
Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More
Because viruses must bind to cell surface molecules to initiate replication, the use of soluble receptors to block virus infection has long been an attractive therapeutic option. Soluble receptors have been developed that block infection with rhinoviruses and HIV-1, but these have not been licen... Read More
The abilities of bacterial organisms to utilize the various strategies to resist antimicrobial compounds are all genetically encoded.
Intrinsic resistance is that type of resistance which is naturally coded and expressed by all (or almost all) strains of that particular bacterial species. An... Read More
An otherwise balanced review of selected aspects of Ebolavirus transmission falls apart when the authors hypothesize that ‘Ebola viruses have the potential to be respiratory pathogens with primary respiratory spread.’
The idea that Ebolavirus might become transmitted by the respiratory route ... Read More