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Treating hepatitis C by blocking a cellular microRNA

Miravirsen is a drug that binds to and blocks the function of a cellular microRNA called miR-122 that is required for the replication of hepatitis C virus (HCV). Treatment of chimpanzees chronically infected with HCV with this drug leads to suppression of viral replication. The results of a phas... Read More

Under the Microscope and the new science blog network by PopSci

Popular Science has just launched a new science blogging network with 13 blogs. Among them are two that have a focus on microbiology, Under the Microscope by JA Tetro and Our Modern Plague by Brooke Borel. Each blog has an inaugural post that outlines the author's vision for future subject matte... Read More

A few reminiscences on Hilary Koprowski

Virologist Hilary Koprowski died on 11 April 2013 at the age of 96. His main accomplishments are nicely summarized in the New York Times, but for a more comprehensive overview of his life, I highly recommend his biography Listen to the Music by Roger Vaughan. I did not have many opportunities to... Read More

TWiP 75 letters


David writes (re lice and iron):


All I remember that I know is that one time I let my cat endure a heavy flea infestation for an unconscionably long time. I redeemed myself, if at all, by the knowledge that I slept with her a lot, and so endured a share myself (b... Read More

De-discovering pathogens: Viral contamination strikes again

Do you remember the retrovirus XMRV, initially implicated as the cause of chronic fatigue syndrome, and later shown to be a murine virus that contaminated human cells grown in mice? Another virus thought to be associated with human disease has recently been shown to be a contaminant, derived fro... Read More

Interactive Handwashing Advice

Pharmaceutical experts NSF DBA have created an interactive guide to hand washing.
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American Academy of Microbiology's new FAQ: West Nile Virus, July 2013

Where does the virus come from? How is it spread? Can we predict when and where outbreaks will occur? What factors determine how sick a person will become if they are infected with West Nile virus?

To help answer the many questions people have about this multi-faceted virus, the American Acad... Read More

BacterioFiles 175 - Bacteria Build Better Biofilms

This episode: Engineered bacteria can be made to produce many different useful kinds of biofilm!


(10.5 MB, 11.5 minutes)


Show notes: 
News item 1/ Read More

Discover Your Inner Scientist: Wolbachia In Nashville 2013

A CNN iReport about an integrative lab series known as the Wolbachia in Nashville includes area high school students from School for Science and Math at Vanderbilt with the purpose of bringing real-world scientific research on microbes into high school biology classes. Angela Eeds, director with... Read More

Bat SARS-like coronavirus that infects human cells

The SARS pandemic of 2002-2003 is believed to have been caused by a bat coronavirus (CoV) that first infected a civet and then was passed on to humans. The isolation of a new SARS-like coronavirus from bats suggests that the virus could have directly infected humans. Read More

The wall of polio

The Polio Wall of Fame is a set of fifteen sculptured busts of 17 individuals who made important contributions to understanding and preventing poliomyelitis. The busts are mounted on an exterior wall of Founder’s Hall at the Roosevelt Warm Springs Institute for Rehabilitation in Warm Springs, Ge... Read More

Learn "How Microbes can Help Feed the World," by reading the Academy's newest report

In order to feed the growing global population that is expected to reach 9 billion by 2050, agricultural yields will need to increase by 70-100%. However, increasing this yield using current methods is not a viable option. Not only is it environmentally damaging, it is also not economically feas... Read More

Interview with Dr. Amy Apprill

Amy Apprill is a researcher of Marine Microbiology. Her work focuses on the relation of Bacteria and Archaea to the health and ecology of marine animals. Her interest is on how animal associated microbes reflect the alterations in the surrounding marine environment that may be related to climate... Read More

ASM GM 2014 - The Next Emerging Threat

Over the past few decades there appears to have been a never-ending stream of emerging diseases from AIDS to SARS and now MERS. Predictions are that global warming will bring... Read More

BacterioFiles Micro Edition 155 - Cells Save Superannuated Sequences

This episode: Bacteria are able to incorporate DNA from the environment into their genomes, even if it's thousands of years old!


(9.6 MB, 10.5 minutes)


Show notes: 
Read More

ASMCUE, Citizen Science, and a Surprise!

In this blog entry, I discuss a talk I attended at ASMCUE about "Citizen Science" and how some of my own work appeared in that talk! It is a vital that we scientists explain not just what we do, but why it is so fascinating to us...by involving the public! Read More

Freshmen, Extra Credit, and Different Ways of Learning

In this blog post, I show how students in my freshman "introduction to cell and molecular biology" course used "creativity"-based approaches to better understand concepts in the course---as they prepare for their upcoming final exam. I believe that this kind of approach truly helps with student... Read More

How naked is naked? Scales of the Gymnamoeba (naked amoeba) show remarkable details!

In memory of Eugéne Penard (1855-1954) we have created a website to show the variety and beauty of amoeboid organisms in light- and electron-microscopic images. Read More

Stop Action Videos, Animation, and Bdellovibrio

My wife, who is a mathematician and artist, made a stop motion video using Play-Doh that represents the life cycle of the bacterial predator, Bdellovibrio. This brings together interesting microbes, animation, and thoughts about what students might do to understand processes in microbiology! Read More

Let's declare WAAAR to antimicrobial resistance

We must change how antibiotics are used and adopt proactive strategies, similar to those used to save endangered species. Preservation of the efficacy of antibiotics and to stabilization of antibiotic-susceptible bacterial ecosystems should be global goals.

We urge all of you to participate i... Read More

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