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Getting Started with MicrobeWorld

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New Powerful Sweet Antibiotic against Superbugs was Found

Scientists from the University of Queensland and a biotechnology company discovered a new class of antibiotics, which is a kind of synthetic sugar. And the new antibiotics can significantly decrease the drug resistance caused by bacteria, and kill them. These new antibiotics can be a powerful dr... Read More

Melioidosis: The Most Neglected Tropical Disease

The ASM Biothreats conference covers preparation for, handling during, and analysis of infectious disease outbreaks, and includes session on research, response, and policies on biological threats and emerging infectious diseases. Most sessions cover broad topics such as emergency preparedness, v... Read More

Borrelia burgdorferi / host interactome

Referenced dataset of host/pathogen interactions for Borrelia burgdorferi: linked to Kegg pathway interactome analysis Read More

Designer viruses for killing tumor cells

A major goal of viral oncotherapy – the use of viruses to destroy tumors – is to design viruses that kill tumor cells but not normal cells. Two adenoviruses provide perfect examples of how this specificity can be achieved.

Adenovirus CG0070, designed to treat bladder cancer, and adenovirus O... Read More

TWiV 439: The purloined envelope

Paul Bieniasz joins the TWiV team to talk about the co-option, millions of years ago, of an endogenous retrovirus envelope protein by hominid ancestors for host defense against viral infection.


Hosts: Vince... Read More

New vaccines againts zika can prevent neurological disorders in newborn mice

Two vaccines against Zika virus developed at the University of Pittsburgh School of Medicine have successfully conveyed immunity from female mice to pups conceived weeks after the mother's vaccination.

When challenged with Zika virus within a week of their birth, both vaccines protected the p... Read More

A bacterial role in breast cancer development and prevention

Microbial infection is implicated in an ever-growing number of types of cancer. Adding to the already long list of microbial-associated cancers, an increasing body of evidence suggests breast cancer may also be associated with a specific microbial milieu. A report in Applied and Environmental Mi... Read More

Viruses Could Help Fight Deadly Superbugs.

Viruses that are harmless to humans might help fight the deadly scourge of bacteria that can't be treated with antibiotics, researchers say.

These viruses could be used in hand santizers, and to treat exposed surfaces in hospitals, which are hotbeds of antibiotic resistance, the researchers n... Read More

"Never Really Alone" with Margaret McFall-Ngai

Last Fall, the great Dr. Margaret McFall-Ngai "virtually visited" my freshman writing class at the University of Puget Sound to discuss symbiosis and Microbial Supremacy with my new students. I had my students read some papers by Dr. McFall-Ngai (including the wonderful "Animals in a Microbial ... Read More

A virus that melts sea stars

Sea stars are lovely marine invertebrates with a round central body connected to multiple radiating legs (photo credit). In the past year millions of sea stars in the west coast waters of North America have melted into piles of slime and ossicles. Sea star associated densovirus might be the caus... Read More

Chlorhexidine use may select for colistin resistance

Infection control is a vital part of maintaining a safe healthcare facility, and the use of biocides and disinfectants to eliminate potential pathogens is an important part of infection control strategy. Pathogens can spread among patients via transfer to surfaces like doors, floors, and counter... Read More

My First #LuxArt Class Competition!

In this blog post, I discuss making student designed artwork using bioluminescent bacteria as "paint." As student "buy in" is critical for any course, such fun "creative" approaches act synergistically to improve learning and outcomes. Feel free to vote on your top six images---the students ar... Read More

TWiV 440: I hardly noumeavirus

No problem not being nice to Dickson in this episode, because he's absent for a discussion of a new giant virus that replicates in the cytoplasm yet transiently accesses the nucleus to bootstrap infection.


Hosts:  Read More

Microbiology, Creativity, and Extra Credit

In this blog post, I share the creative projects that my Biology 350 (Microbiology) micronauts created this semester. They range from video parodies, to prose poems, to short-short stories to sculptures and needlepoint. Enjoy! Read More

ASM CEO Stefano Bertuzzi on World AIDS Day 2016

I hope we have all had an opportunity over the past holiday weekend to give thanks for what we have—it is important to step back and reflect from time to time on the many benefits and advantages we have. It can help us realize what we have achieved, and the multitude of people and resources that... Read More

Viruses in the extreme

Many microbes live in extreme environments, encountering conditions that are very hot, very cold, highly acidic, or very salty. The viruses that infect such microbes must also be able to retain infectivity in extreme conditions. How do they do it?

Clues come from the observations that the gen... Read More

Nobel Laureates and Ebola virus quarantine

After the governors of New York and New Jersey decided that health workers who have returned from the Ebola virus outbreak in West Africa should be subject to a 21-day quarantine, two Nobel laureates entered the fray. Bruce Beutler feels that the quarantine is the right thing to do, while Peter ... Read More

Your next migraine might be thanks to your mouth microbes

When Antonio Gonzalez began doctoral studies in Rob Knight’s laboratory, then at University of Colorado, Boulder, the computer scientist quickly learned about microbes and their connection to human health. He soon found a connection to his wife’s health jumping out of the literature at him.

H... Read More

Interview with David Baltimore, PhD, Principles of Virology, 4th Edition

Vincent Racaniello of the This Week in Virology podcast interviews David Baltimore, PhD, California Institute of Technology, about his career and professional experience in the field of virology. Baltimore received a 1975 Nobel laureate in Physiology or Medicine for work on the interaction betwe... Read More

Viroids, infectious agents that encode no proteins

Genomes of non-defective viruses range in size from 2,400,000 bp of dsDNA (Pandoravirus salinus) to 1,759 bp of ssDNA (porcine circovirus). Are even smaller viral genomes possible? The subviral agents called viroids provide an answer to this question.

Viroids, the smallest known pathogens, ar... Read More
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