The stability of Middle East respiratory syndrome coronavirus (MERS-CoV) was determined at 20°C – 40% relative humidity (RH); 30°C – 30% RH and 30°C – 80% RH. MERS-CoV was more stable at low temperature/low humidity conditions and could still be recovered after 48 hours. During aerosolisation of... Read More
Most gut bacteria are beneficial, aiding food digestion, producing vitamins, and protecting against harmful bacteria. If left unchecked, however, harmful bacteria can excrete... Read More
PLOS ONE authors Cybulski, Clements and Prakash describe an ultra-low-cost origami-based approach for large-scale manufacturing of microscopes, specifically demonstrating brightfield, darkfield, and fluorescence microscopes. Merging principles of optical design with origami enables high-volume f... Read More
Genomes of non-defective viruses range in size from 2,400,000 bp of dsDNA (Pandoravirus salinus) to 1,759 bp of ssDNA (porcine circovirus). Are even smaller viral genomes possible? The subviral agents called viroids provide an answer to this question.
Viroids, the smallest known pathogens, ar... Read More
In this blog post, I describe how I use the commonly available pGLO plasmid to teach freshman students basic concepts about transformation, receptor recognition, drug resistance mechanisms, and gene regulation. Oh, and fluorescence via GFP! Read More
Based on a Twitter conversation with two microbiology educators, I share a story of how (through a survey) I encourage students to look deeply at their study strategies and promote "ownership" in their classroom experience. Read More
Reticuloendotheliosis viruses (REVs) are retroviruses that cause a rare disease of gamebirds and waterfowl that includes anemia, immunosuppression, neoplasia, runting, and abnormal feathering. Since the first isolation of REV from a turkey in 1957, REVs were believed to be strictly avian viruses... Read More
Satellites are subviral agents that differ from viroids because they depend on the presence of a helper virus for their propagation. Satellite viruses are particles that contain nucleic acid genomes encoding a structural protein that encapsidates the satellite genome. Satellite RNAs do not encod... Read More
Viruses can be broadly classified according to whether or not the particle is enveloped – surrounded by a membrane taken from the host cell – or naked. Some naked viruses apparently are more modest than we believed. Read More
You don’t want to miss asm2014. We’ve compiled a list of five things not to miss at the 114th American Society for Microbiology General Session.
Click the "source" link or copy/paste this URL into your browser: http://blog.puritanmedproducts.com/bid/383376/asm2014-Five-Things-Not-to-Miss-at-... Read More
In this blog post, I discuss how students begin to find their "path" to a career that they will love in science. I aIso write about the late, great Richard Feynman. Read More
The entry of enveloped viruses into cells begins when the membrane that surrounds these virus particles fuse with a cell membrane. The process of virus-cell fusion must be tightly regulated, to make sure it happens in the right cells. The fusion activity of measles viruses isolated from the brai... Read More
If the reader does not believe that viroids and satellites are distinctive, then surely prions, infectious agents composed only of protein, must impress.
The question of whether infectious agents exist without genomes arose with the discovery and characterization of infectious agents associat... Read More
During my visit to the University of Vermont today I had lunch with seven talented Microbiology Ph.D. students. One of them asked me what was an important quality to have for achieving success in science. I said without hesitation, ‘Be curious’. It’s the answer I always give. Being curious is th... Read More
Contrary to popular belief, urine is not sterile and the bacteria in it may be associated with overactive bladder (OAB) in some women. Presenters will discuss their research ... Read More
The American Academy of Microbiology has released its newest report about the West Nile virus. Questions answered include: Can West Nile virus outbreaks be prevented? Why do some people get West Nile fever? How did the West Nile virus spread across the country so quickly?
The free report can ... Read More
The journal "RNA Biology" just published a memorial issue dedicated to the late, great Carl Woese. The entire issue is open access. I have a small contribution, but the entire issue is filled with great science, wonderful memories, and a fine celebration of a scientist who changed the way we l... Read More
For what may be the first time, researchers have discovered a virus inside a host with a non-standard nuclear genetic code — one that differs from the standard genetic code that almost all living things use to produce proteins.
“The finding is significant because it shows that these viruses... Read More
Immunology Explained Through Poetry - What happens when one touches a poison ivy?
Billy was at summer camp,
And wanted to feel like a champ,
So he searched for a flower,
That would stop Susie’s glower,
But found poison ivy instead.
While Billy was later playing,
He had no i... Read More
The first immortal human cell line ever produced, HeLa, originated from a cervical adenocarcinoma taken from Henrietta Lacks. The cell line grew so well that it was used in many laboratories and soon was found to contaminate other cell lines. Now HeLa RNA has made its way into human sequence dat... Read More