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Why do viruses cause disease?

Virulence, the capacity to cause disease, varies markedly among viruses. Some viruses cause lethal disease while others do not. For example, nearly all humans infected with rabies virus develop a disease of the central nervous system which ultimately leads to death. In contrast, most humans are ... Read More

TWiV 270: Homeland virology

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Hosts: Vincent Racaniello and Rich Condit Read More

End of moratorium on influenza H5N1 research

In early 2012 influenza virus researchers around the world decided to stop working on highly pathogenic avian influenza H5N1 virus. This decision came after work from the Fouchier and Kawaoka laboratories revealed the isolation of influenza H5N1 strains that can be passed among ferrets by aeroso... Read More

Cyanine dyes - Non-sulfonated and Sulfonated cyanines Lumiprobe explains

Sulfonated and non-sulfonated cyanines exhibit very similar fluorescent properties. Non-sulfonated cyanines must be dissolved in organic co-solvent (DMF or DMSO) prior to use, and added to a solution of target molecule in aqueous buffers. Recommended volume of co-solvent should be 10% for Cy3, C... Read More

Bovine TB and badgers - why it all matters

With the news of a trial badger cull in England as an attempt to reduce the levels of Mycobacterium bovis or bovine TB in cattle, this post reviews why it is so important to reduce the level of the organism in the cattle and badger populations. Read More

Reducing antibiotic requests from patients with viral infections

For anyone interested in Antibiotic Awareness Week, a big part of the story is that patients (or their parents) demand antibacterials even for viral infections. And doctors often comply, just to get rid of them (the patients, that is). This high-resolution PDF can be printed out for waiting ro... Read More

Going viral on Science Sunday Hangout on Air

I joined Buddhini Samarasinghe and Scott Lewis on a Science Sunday Hangout on Air to talk about my career in virology: how I came to be interested in viruses, and what goes on in my laboratory. You can find hangouts and more at the ScienceSunday community.


{youtube}WpLH4gRk9gc{/youtub... Read More

El podcast del Microbio Nº 350. Están vivos (They Live)



























El podcast del microbio Nº 350 summarize the article writen by Nasir A, Kim KM, & Caetano-Anolles and published in BMC evolutionary biology on the hypothesis that giant viruses (mimivirus) are a fourth doma... Read More

Viral fiber art

Viruses inspire many different types of art, but I was unaware of the number of people who make viruses out of fiber! Keep reading for some photographs of what I have found. Read More

Fourth Season of El Podcast del Microbio: Francisco Javier Balmis



























The new season of El podcast del Microbio has begun. The radio broadcast Nº 331, 332 and 333 are dedicated to Francisco Javier Balmis, the Spanish physician who headed an 1804 expedition to Spanish America t... Read More

TWiV 283: No Reston for the weary



 Hosts: Vincent RacanielloAlan Dove Read More

TWiV 296: The real Batman, Linfa Wang

Vincent visits the Australian Animal Health Laboratory in Geelong, Australia and speaks with Linfa about his work on bats and bat viruses.


Hosts: Vincent Racaniello


Guest:  Read More

A saga of HeLa cells

We have been using HeLa cells in my laboratory since 1982, when I arrived at Columbia University Medical Center fresh from postdoctoral work with David Baltimore at MIT. I brought with me a line of HeLa cells and used them for 30 years for our research on viruses. Here is a story of how we lost ... Read More

Horizontal transfer of antibiotic resistance genes among gram negative bacteria in sewage and lake water and influence of some physico-chemical parameters of water on conjugation process

Transfer of antibiotic resistance genes among gram negative bacteria in sewage and lake water and easy access of these
bacteria to the community are major environmental and public health concern. The aim of this study was to determine transfer of the
antimicrobial resistance genes from resista... Read More

The gender bias of science faculty

If you were a science professor, and you received two equally strong applications for the position of laboratory manager, one from a female, one from a male, which one would you pick? The answer might surprise you. Read More

Engineering adenoviruses for gene therapy

This is a movie by David Bella, Ph.D., at the University of Glasgow Centre for Virus Research showing the results of an analysis of Adenovirus binding to blood coagulation factor X, performed in collaboration with Professor Andrew H Baker in the University of Glasgow.

The animation was creat... Read More

Proposed US policy on dual use research of concern

The US Office of Science and Technology Policy recently released proposed guidelines for maximizing the benefits and minimizing misuse of life sciences research. The measures establish oversight responsibilities for universities and other institutions that receive Federal funding. Read More

Virologists plan influenza H7N9 gain of function experiments

A group of virologists lead by Yoshihiro Kawaoka and Ron Fouchier have sent a letter to Nature and Science outlining the experiments they propose to carry out with influenza H7N9 virus. Avian influenza H7N9 virus has caused over 130 human infections in China with 43 fatalities. The source of the... Read More

Next-Generation Site-Directed Transgenesis in the Malaria Vector Mosquito Anopheles gambiae: Self-Docking Strains Expressing Germline-Specific phiC31 Integrase

Diseases transmitted by mosquitoes have a devastating impact on global health and the situation is complicated due to difficulties with both existing control measures and the impact of climate change. Genetically modified mosquitoes that are refractory to disease transmission are seen as having ... Read More

Polio-like paralysis in California

Recently a number of children in California have developed a poliomyelitis-like paralysis. The cause of this paralysis is not yet known, and information about the outbreak is scarce. However, acute-flaccid paralysis is not uncommon (California would be expected to report about 75 cases a year, b... Read More

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