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Implications of finding poliovirus in sewers of Brazil and Israel

Wild poliovirus has been detected in the sewers of Brazil and Israel. Fortunately, no cases of poliomyelitis have been reported in either country. Why is poliovirus present in these countries and what are the implications for the eradication effort?

Wild type poliovirus (e.g. not vaccine-deri... Read More

Viral gifts

If you are looking for the perfect present for that infectious person in your life, there are many microbe-themed possibilities. Here are some suggestions, from t-shirts, to watercolors, glass sculptures, and paper to wrap it in. Read More

Origin of segmented RNA virus genomes

Segmented genomes abound in the RNA virus world. They are found in virus particles from different families, and can be double stranded (Reoviridae) or single stranded of (+) (Closteroviridae) or (-) (Orthomyxoviridae) polarity. Our recent discussion of the advantages of a segmented viral genome,... Read More

TWiV 341: Ebolavirus experiences

Host: Vincent Racaniello


Guests: Adam Kucharski Read More

ASM GM 2014 - The Potential Role of Gut Microbes in Autism

Most gut bacteria are beneficial, aiding food digestion, producing vitamins, and protecting against harmful bacteria. If left unchecked, however, harmful bacteria can excrete... Read More

Attenuated influenza vaccine enhances bacterial colonization of mice

Infection with influenza virus is known to increase susceptibility to bacterial infections of the respiratory tract. In a mouse model of influenza, increased bacterial colonization was also observed after administration of an infectious, attenuated influenza virus vaccine. Primary influenza viru... Read More

Avian influenza H7N7 virus outbreak: Lessons for H7N9

An outbreak of high-pathogenicity avian influenza H7N7 virus that took place on 255 poultry farms in the Netherlands during 2003 has been used to provide clues about the current avian influenza H7N9 viruses in China. During the Dutch outbreak 453 humans showed symptoms of illness and 89 were con... Read More

John Holland, 83

Virologist John Holland passed away on 11 October 2013. I asked former members of his laboratory for their thoughts on his career and what he meant to them. Read More

Probiotics vs Antibiotics? You're asking the wrong question.

'The question of whether someone should be taking a probiotic or an antibiotic is one I hear fairly frequently. The answer, in short, is that this isn't a question of either / or! At this stage in time, with this level of research on probiotics, it is not right to suggest one stops taking their... Read More

BacterioFiles 219 - Fungi Facilitate Photosynthetic Fuels

This episode: Fungi can act like sticky nets to help harvest algae for biofuels!


(8.3 MB, 9 minutes)


Show notes: 
News item/ Read More

The science-themed art of Deb Sklut

During my visit to Berkeley, CA to record TWiV #228, I met Deb Sklut, an artist who is inspired by the power of science. I recorded a brief conversation with Deb which you can view below. Her work can be found at SqueakySqueegeeArt.etsy.com. Read More

Stability of MERS Under Different Environmental Conditions (research)

The stability of Middle East respiratory syndrome coronavirus (MERS-CoV) was determined at 20°C – 40% relative humidity (RH); 30°C – 30% RH and 30°C – 80% RH. MERS-CoV was more stable at low temperature/low humidity conditions and could still be recovered after 48 hours. During aerosolisation of... Read More

Foldscope: Origami-Based Paper Microscope

PLOS ONE authors Cybulski, Clements and Prakash describe an ultra-low-cost origami-based approach for large-scale manufacturing of microscopes, specifically demonstrating brightfield, darkfield, and fluorescence microscopes. Merging principles of optical design with origami enables high-volume f... Read More

MERS-CoV genome found in dromedary camels

Middle Eastern respiratory syndrome coronavirus (MERS-CoV), first identified in the fall of 2012 in a Saudi Arabian patient, has since infected over 160 individuals, causing 71 deaths. Identifying the source of infection is important for efforts to prevent further infections. Recently two studie... Read More

Viroids, infectious agents that encode no proteins

Genomes of non-defective viruses range in size from 2,400,000 bp of dsDNA (Pandoravirus salinus) to 1,759 bp of ssDNA (porcine circovirus). Are even smaller viral genomes possible? The subviral agents called viroids provide an answer to this question.

Viroids, the smallest known pathogens, ar... Read More

Covering up a naked virus

Viruses can be broadly classified according to whether or not the particle is enveloped – surrounded by a membrane taken from the host cell – or naked. Some naked viruses apparently are more modest than we believed. Read More

Stop Action Videos, Animation, and Bdellovibrio

My wife, who is a mathematician and artist, made a stop motion video using Play-Doh that represents the life cycle of the bacterial predator, Bdellovibrio. This brings together interesting microbes, animation, and thoughts about what students might do to understand processes in microbiology! Read More

Teaching Freshmen about Transformation, Drug Resistance, and Gene Regulation!

In this blog post, I describe how I use the commonly available pGLO plasmid to teach freshman students basic concepts about transformation, receptor recognition, drug resistance mechanisms, and gene regulation. Oh, and fluorescence via GFP! Read More

Dispatches from the Teaching Front, Part 1: Student Self-Evaluation

Based on a Twitter conversation with two microbiology educators, I share a story of how (through a survey) I encourage students to look deeply at their study strategies and promote "ownership" in their classroom experience. Read More

Satellites - the viral kind

Satellites are subviral agents that differ from viroids because they depend on the presence of a helper virus for their propagation. Satellite viruses are particles that contain nucleic acid genomes encoding a structural protein that encapsidates the satellite genome. Satellite RNAs do not encod... Read More
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