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A chromosome in every cell: PprA funcitons in chromosome segregation after Deinococcus radiodurans irradiation

Exposure to reactive oxygen species, exposure to ionizing radiation, exposure to UV light – all of these are dangerous because of their potential to alter DNA sequences. Changes in DNA can affect a protein coding sequence, potentially influencing its function, but changes in regulatory regions c... Read More

ASM GM 2014 - Windshield Wiper Fluid: A Source of Legionnaires?

A form of bacteria responsible for respiratory illness, including the deadly pneumonia known as Legionnaire's disease, may be able to grow in windshield washer fluid and was isolated from nearly 75% of school buses tested in one district in Arizona. The participant will discuss findings from ... Read More

Potential Zika virus risk estimated for 50 US cities

BOULDER - Key factors that can combine to produce a Zika virus outbreak are expected to be present in a number of U.S. cities during peak summer months, new research shows. Read More

Inspiration for 2015 via the Late, Great Randy Pausch!

The late computer scientist Randy Pausch wrote many inspirational things about life and academia during his struggle with pancreatic cancer. As we approach 2015, his words are helpful to me, and perhaps to others. About life, about academia, about helping others...and making our dreams come tr... Read More

Getting closer to understanding Zika virus, one genome at a time

Several papers published in Genome Announcements recently describe the sequences of new Zika virus isolates. Scientists have known the genomic sequence of at least one Zika virus isolate since 2007, but continue to publish newly isolated strains. What is the importance of these additional sequen... Read More

A promising Ebolavirus antiviral compound

Remember Ebolaviruses? Many people are still working on vaccines and therapeutics. Here is a very nice story on a promising antiviral compound that is very effective at preventing disease in monkeys. But it doesn't work in mice - it's degraded. You know what they say - mice lie, monkeys exaggera... Read More

MMP #12: Hydrogen from ground rocks can furnish microbial ecosystems with energy to drive growth.

Host: Jeff Fox with special guest, Jon Telling.


Jon Telling of Bristol University in Bristol, United Kingdom talks with Jeff Fox about his findings suggesting that the grinding of glaciers over rocks can liberate hydrogen, which, in turn, drives the growth of methanogens within microb... Read More

On a Cellular Level, We Are ALL Overachievers!

In this blog post, I show a science-cartoon by the great "Beatrice the Biologist" that illustrates an important point in my freshman introductory cell and molecular biology course: no matter how tired we might be, we are incredibly busy on a cellular level! Beatrice is a fine artist who underst... Read More

Why do viruses cause disease?

Virulence, the capacity to cause disease, varies markedly among viruses. Some viruses cause lethal disease while others do not. For example, nearly all humans infected with rabies virus develop a disease of the central nervous system which ultimately leads to death. In contrast, most humans are ... Read More

"Never Really Alone" with Ed Yong!

Each Fall, I teach a freshman writing class about symbioses and parasitism. I was very lucky to get some pretty famous people to "Skype" or "Google Hang Out" in to visit my class. Last Fall, one of my "tele-speakers" was the fabulous science writer and very funny fellow Ed Yong. The students ... Read More

The incubation period of a viral infection

The time before the symptoms of a viral infection appear is called the incubation period. During this time, viral genomes are replicating and the host is responding, producing cytokines such as interferon that can have global effects, leading to the classical symptoms of an acute infection (e.g.... Read More

Broad-spectrum antimicrobials: Considering ‘Holobiont’ welfare

The discovery of antibiotics (also referred to as antimicrobials) is perhaps the most revolutionary outcome in the medical sciences during the twentieth century, and has allowed medical practitioners to treat a wide range of bacterial infections; and therefore, antimicrobials are the most common... Read More

Part of MERS-CoV nucleotide sequence found in a bat

What is wrong with this paragraph from today’s New York Times that describes the origin of the Middle East Respiratory Syndrome (MERS) coronavirus:

Health officials confirmed Wednesday that bats in Saudi Arabia were the source of the mysterious virus that has sickened 96 people in the Middle ... Read More

A saga of HeLa cells

We have been using HeLa cells in my laboratory since 1982, when I arrived at Columbia University Medical Center fresh from postdoctoral work with David Baltimore at MIT. I brought with me a line of HeLa cells and used them for 30 years for our research on viruses. Here is a story of how we lost ... Read More

MOOC Pandemics, new viral infections

New Massive Online Open Courses (MOOC) in Spanish about Pandemics and new viral infections.

An online open course about basic concepts of viruses and pandemics. We answer questions as what is a virus?, how a virus multiplies inside a cell?, what is a pandemic?, why appear new influenza virus ... Read More

Here's What Would Really Happen If You Stopped Bathing

You've probably gone a few days without showering -- maybe a week. But let's say you don't bathe for days on end -- as in you use no soap, no water, no nothing.

What would happen?

Click "source" to find out. Read More

The neuraminidase of influenza virus

The influenza virus particle is made up of the viral RNA genome wrapped in a lipid membrane (illustrated). The membrane, or envelope, contains three different kinds of viral proteins. The hemagglutinin molecule (HA, blue) attaches to cell receptors and initiates the process of virus entry into c... Read More

A novel plate based method for screening DOPA / melanin producing bacteria

Team of researchers guided by Dr.Sarita G Bhat had developed a novel plate based screening technique for DOPA/melanin producing bacteria.Screening was based upon the clear zone formation on a medium suplemented with L-tyrosine.This new approach can be utilized in faster and accurate screening of... Read More

Treatment of Ebola virus infection with brincidofovir

The Liberian man who was diagnosed with Ebola virus infection after traveling to Dallas, Texas, was treated with an antiviral drug called brincidofovir. This drug had originally been developed to treat infections with DNA-containing viruses. Why was it used to treat an Ebola virus infection? Read More

A virus-like particle vaccine against RSV is safe and effective in mice

Pneumonia remains a serious worldwide problem, especially among the young, elderly, and immunocompromised. Over 900,000 children die each year due to the disease, and respiratory syncytial virus (RSV) is the most common viral cause (Streptococcus pneumoniae and Haemophilus influenzae type b bein... Read More
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