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Horizontal transfer of antibiotic resistance genes among gram negative bacteria in sewage and lake water and influence of some physico-chemical parameters of water on conjugation process

Transfer of antibiotic resistance genes among gram negative bacteria in sewage and lake water and easy access of these
bacteria to the community are major environmental and public health concern. The aim of this study was to determine transfer of the
antimicrobial resistance genes from resista... Read More

Treatment of Ebola virus infection with brincidofovir

The Liberian man who was diagnosed with Ebola virus infection after traveling to Dallas, Texas, was treated with an antiviral drug called brincidofovir. This drug had originally been developed to treat infections with DNA-containing viruses. Why was it used to treat an Ebola virus infection? Read More

Let's declare WAAAR to antimicrobial resistance

We must change how antibiotics are used and adopt proactive strategies, similar to those used to save endangered species. Preservation of the efficacy of antibiotics and to stabilization of antibiotic-susceptible bacterial ecosystems should be global goals.

We urge all of you to participate i... Read More

TWiV 324: Viruses in the miR may appear more numerous

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiV 325: Wildcats go viral

Hosts: Vincent Racaniello


Guests: Rollie Clem and Lorena Passarelli


{audio... Read More

Rhizopus microsporus

Rhizopus microsporus
It causes human mucormycosis and bovine mycotic abortion.
It is distinguished from R.arrhizus by its shorter stalk, and smaller sporangia and spores.
Variant forms
Var.oligosporus : has elongated columellae ; spores less obviously striated.
Var.rhizopodiformis : has ... Read More

An unexpected benefit of inactivated poliovirus vaccine

The polio eradication and endgame strategic plan announced by the World Health Organization in 2014 includes at least one dose of inactivated poliovirus vaccine (IPV). Since 1988, when WHO announced the polio eradication plan, it had relied exclusively on the use of oral poliovirus vaccine (OPV)... Read More

TWiP 82 letters


Allan writes:


Dear Vincent, Dickson and Daniel,


I like your idea of a TWIP coffee mug prize (or maybe a mug discount).


In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More

What we are not afraid to say about Ebola virus

In a recent New York Times OpEd entitled What We’re Afraid to Say About Ebola, Michaeal Osterholm wonders whether Ebola virus could go airborne:

You can now get Ebola only through direct contact with bodily fluids. If certain mutations occurred, it would mean that just breathing would put one... Read More

Part of MERS-CoV nucleotide sequence found in a bat

What is wrong with this paragraph from today’s New York Times that describes the origin of the Middle East Respiratory Syndrome (MERS) coronavirus:

Health officials confirmed Wednesday that bats in Saudi Arabia were the source of the mysterious virus that has sickened 96 people in the Middle ... Read More

MWV94 - TWiM #99: Careers in Biodefense

Hosts: Vincent Racaniello


Guests: Maria Julia Marinissen, Read More

El podcast del Microbio Nº 350. Están vivos (They Live)



























El podcast del microbio Nº 350 summarize the article writen by Nasir A, Kim KM, & Caetano-Anolles and published in BMC evolutionary biology on the hypothesis that giant viruses (mimivirus) are a fourth doma... Read More

Visiting biosafety level-4 laboratories

Experiments with the most dangerous human viruses, such as Ebola virus and Lassa virus, are carried out in biosafety level 4 (BSL-4) laboratories. Since visiting the Northeast Infectious Diseases Laboratory BSL-4 and releasing the documentary video Threading the NEIDL, I was given the opportunit... Read More

Transmission of Ebola virus

As the West African epidemic of Ebola virus grows, so does misinformation about the virus, particularly how it is transmitted from person to person. Ebola virus is transmitted from human to human by close contact with infected patients and virus-containing body fluids. It does not spread among h... Read More

Chemistry: A festive ferment

Rare is the holiday meal that does not owe many of its pleasures to invisible cooks with tongue-twisting names. Do you enjoy charcuterie and pickles? Bread with cultured butter? A drizzle of vinaigrette on this or that? A bit of cheese? Some chocolates? Wine, beer or cider? Then raise a glass to... Read More

BacterioFiles 207 - Microbe Messages Mire Malaria Movement

This episode: Gut microbes may induce an immune response that protects against malaria!


(10.2 MB, 11.2 minutes)


Show notes: 
News item/... Read More

Incidence of asymptomatic human influenza A(H5N1) virus infection

When virologists Fouchier and Kawaoka were isolating avian influenza H5N1 viruses that could transmit among ferrets by aerosol, there was consternation from some quarters that such viruses might escape from the laboratory and cause a pandemic in humans. Part of the fear came from the fact that t... Read More

The gender bias of science faculty

If you were a science professor, and you received two equally strong applications for the position of laboratory manager, one from a female, one from a male, which one would you pick? The answer might surprise you. Read More

End of moratorium on influenza H5N1 research

In early 2012 influenza virus researchers around the world decided to stop working on highly pathogenic avian influenza H5N1 virus. This decision came after work from the Fouchier and Kawaoka laboratories revealed the isolation of influenza H5N1 strains that can be passed among ferrets by aeroso... Read More

Retroviruses R us

About eight percent of human DNA is viral – remnants of ancestral infections with retroviruses. These endogenous retroviral sequences do not produce infectious viruses, and most are considered to be junk DNA. But some of them provide important functions. The protein called syncytin, which is ess... Read More
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