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Why do viruses cause disease?

Virulence, the capacity to cause disease, varies markedly among viruses. Some viruses cause lethal disease while others do not. For example, nearly all humans infected with rabies virus develop a disease of the central nervous system which ultimately leads to death. In contrast, most humans are ... Read More

TWiM 89 Letters

Peter writes:


Dear Michele,


Prof. Szybalski might have been referring to a truck with a wood gas generator


Apparently they are still in use north of the b... Read More

Viral fiber art

Viruses inspire many different types of art, but I was unaware of the number of people who make viruses out of fiber! Keep reading for some photographs of what I have found. Read More

Inefficient influenza H7N9 virus aerosol transmission among ferrets

There have been 131 confirmed human infections with avian influenza H7N9 virus in China, but so far there is little evidence for human to human transmission. Three out of four patients report exposure to animals, ‘mostly chickens‘, suggesting that most of the infections are zoonoses. Whether or ... Read More

Interview of Cave Microbiologist, Dr. Naowarat Cheeptham (aka Ann)

Dr. Naowarat Cheeptham, is a famous cave microbiologist. Dr. Cheeptham has been fascinated with the world of biology since she was out catching butterflies as a child with her father in her native country, Thailand. Her interest in microbiology developed while studying at Chiang Mai University ... Read More

Fourth Season of El Podcast del Microbio: Francisco Javier Balmis



























The new season of El podcast del Microbio has begun. The radio broadcast Nº 331, 332 and 333 are dedicated to Francisco Javier Balmis, the Spanish physician who headed an 1804 expedition to Spanish America t... Read More

Interview with Dr. Amy Apprill

Amy Apprill is a researcher of Marine Microbiology. Her work focuses on the relation of Bacteria and Archaea to the health and ecology of marine animals. Her interest is on how animal associated microbes reflect the alterations in the surrounding marine environment that may be related to climate... Read More

TWiV 319: Breaking breakbone

The TWiVers review the outcomes of two recent phase 3 clinical trials of a quadrivalent dengue virus vaccine in Asia and Latin America.


Hosts: Vincent Racaniello Read More

Circovirus in Shanghai

Recently thousands of dead and decaying pigs were pulled from rivers in Shanghai and Jiaxing, China. Apparently farmers dumped the animals into the water after the pigs became ill, and porcine circovirus was subsequently detected in the in pig carcasses and in the water. Porcine circoviruses are... Read More

TWiV 304: Given X, solve for EBOV

 The TWiV team consults an epidemiologist to forecast the future scope of the Ebola virus epidemic in West Africa.


Hosts: Vincent Racaniello Read More

BacterioFiles 188 - Rat Residents Relieve Resin Roughness

This episode: Gut bacteria in Mojave desert woodrats help them detoxify and eat toxic creosote bushes!


(10 MB, 10.8 minutes)


Show notes: 
News item/ Read More

Polio-like paralysis in California

Recently a number of children in California have developed a poliomyelitis-like paralysis. The cause of this paralysis is not yet known, and information about the outbreak is scarce. However, acute-flaccid paralysis is not uncommon (California would be expected to report about 75 cases a year, b... Read More

TWiP 78 letters


Meliani writes:


Dear Sir,


My research is focused on the biofilms formation, Motility (swarming and swiming ) and QS in fluorescent Pseudomonas (P. aeruginosa and P. fluorescens).


In laboratory a interaction had been with insect and bacteria metabo... Read More

Interview of Dr. Sikandar K Sherwani, Chairman of MAP

Mr. Sikandar K Sherwani, chairman of Microbiology Association of Pakistan (MAP).
He is a Lecturer of Microbiology (Sp. Immunology & Infectious Diseases) at the Department of Microbiology in Federal Urdu University for Arts, Science & Technology (FUUAST). He is also a research scholar at Immunol... Read More

Going viral on Science Sunday Hangout on Air

I joined Buddhini Samarasinghe and Scott Lewis on a Science Sunday Hangout on Air to talk about my career in virology: how I came to be interested in viruses, and what goes on in my laboratory. You can find hangouts and more at the ScienceSunday community.


{youtube}WpLH4gRk9gc{/youtub... Read More

A saga of HeLa cells

We have been using HeLa cells in my laboratory since 1982, when I arrived at Columbia University Medical Center fresh from postdoctoral work with David Baltimore at MIT. I brought with me a line of HeLa cells and used them for 30 years for our research on viruses. Here is a story of how we lost ... Read More

The incubation period of a viral infection

The time before the symptoms of a viral infection appear is called the incubation period. During this time, viral genomes are replicating and the host is responding, producing cytokines such as interferon that can have global effects, leading to the classical symptoms of an acute infection (e.g.... Read More

Virologists plan influenza H7N9 gain of function experiments

A group of virologists lead by Yoshihiro Kawaoka and Ron Fouchier have sent a letter to Nature and Science outlining the experiments they propose to carry out with influenza H7N9 virus. Avian influenza H7N9 virus has caused over 130 human infections in China with 43 fatalities. The source of the... Read More

TWiP 81 letters


Allan writes:


Dear Vincent & Dickson… and Daniel,


I always enjoy listening to TWIP here in Kona, Hawaii.


Our weather today is 79ºF and clear but we have just experienced a record 25-year overnight low of 54ºF,
(FREEZING, as few of us hav... Read More

Top chefs, artisanal food producers, and microbiologists join forces to explore new tastes and textures

Chefs from top-notch restaurants are reaching out to microbiologists, seeking advice that goes beyond traditional food safety or conventional food-processing concerns. With or without professional scientific advice, some chefs and food producers are doing their own microbiological experiments, s... Read More
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