Viruses are obligate intracellular parasites, which means that they must enter a cell to reproduce. As virions are too large to diffuse passively across the plasma membrane, cellular pathways for uptake of extracellular materials provide entry routes. The first step in entry is adherence of viru... Read More
The American Academy of Microbiology has just released a new report, "Microbe-Powered Jobs: How Microbiologists Can Help Build the Bioeconomy," and along with it, an infographic, that summarizes the main points of the report. The full report can be found here: http://bit.ly/1lk346I, and a link t... Read More
The TWiV team discusses transmission of Ebola virus, and inhibition of Borna disease virus replication by viral DNA in the ground squirrel genome.
Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells.
Host: Read More
Suzanne writes (re Aphids):
The best way to get rid of aphids in the garden (the ants in my yard love to herd them onto my okra) is a sharp stream of water from the hose. Aphids wash right off! They don't tend to come back right away, either.
This episode: Bacteria are able to incorporate DNA from the environment into their genomes, even if it's thousands of years old!
(9.6 MB, 10.5 minutes)
The TWiVocytes answer questions about Ebola virus, including mode of transmission, quarantine, incubation period, immunity, and much more.
The late computer scientist Randy Pausch wrote many inspirational things about life and academia during his struggle with pancreatic cancer. As we approach 2015, his words are helpful to me, and perhaps to others. About life, about academia, about helping others...and making our dreams come tr... Read More
Vincent, Alan, Rich and Kathy discuss how interleukin 10 modulation of Th17 helper cells contributes to alphavirus pathogenesis.
Tengo el gusto de anunciarles que mi curso de virologia esta ahora disponible en Español.
Este trabajo se realizó bajo la dirección de la Dra. Susana López, virologa del Departamento de Genética del Desarrollo y Fisiología Molecular del Instituto de Biotecnología de la Universidad Nacional A... Read More
The discovery of the giant Mimivirus and Megavirus amazed virologists (and also many others). Their virions (750 nanometers) and DNA genomes (1,259,000 base pairs) were the biggest ever discovered, shattering the notions that viruses could not be seen with a light microscope, and that viral geno... Read More
Each year as I teach my undergraduate virology course, I record each lecture and put them online where they are freely accessible. A student in my virology course approached me recently to thank me for making the lectures available online, and wondered why other professors did not so the same. T... Read More
Virulence, the capacity to cause disease, varies markedly among viruses. Some viruses cause lethal disease while others do not. For example, nearly all humans infected with rabies virus develop a disease of the central nervous system which ultimately leads to death. In contrast, most humans are ... Read More
I came across this paper and thought it sounded interesting for a discussion on TWiP:
Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection
There have been 131 confirmed human infections with avian influenza H7N9 virus in China, but so far there is little evidence for human to human transmission. Three out of four patients report exposure to animals, ‘mostly chickens‘, suggesting that most of the infections are zoonoses. Whether or ... Read More
Viruses inspire many different types of art, but I was unaware of the number of people who make viruses out of fiber! Keep reading for some photographs of what I have found. Read More
The new season of El podcast del Microbio has begun. The radio broadcast Nº 331, 332 and 333 are dedicated to Francisco Javier Balmis, the Spanish physician who headed an 1804 expedition to Spanish America t... Read More
El podcast del Microbio Nº 284 summarize the paper by Tong et al published in PNAS about the finding of a distinct lineage of in... Read More