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BacterioFiles 215 - Plasmid Pirates Piezophile Particles

This episode: Deep-sea thermophile bacteriophage is pirated by another scurvy genetic element!


(10.2 MB, 11.2 minutes)


Show notes: 
J... Read More

Inefficient influenza H7N9 virus aerosol transmission among ferrets

There have been 131 confirmed human infections with avian influenza H7N9 virus in China, but so far there is little evidence for human to human transmission. Three out of four patients report exposure to animals, ‘mostly chickens‘, suggesting that most of the infections are zoonoses. Whether or ... Read More

The neuraminidase of influenza virus

The influenza virus particle is made up of the viral RNA genome wrapped in a lipid membrane (illustrated). The membrane, or envelope, contains three different kinds of viral proteins. The hemagglutinin molecule (HA, blue) attaches to cell receptors and initiates the process of virus entry into c... Read More

A saga of HeLa cells

We have been using HeLa cells in my laboratory since 1982, when I arrived at Columbia University Medical Center fresh from postdoctoral work with David Baltimore at MIT. I brought with me a line of HeLa cells and used them for 30 years for our research on viruses. Here is a story of how we lost ... Read More

Circovirus in Shanghai

Recently thousands of dead and decaying pigs were pulled from rivers in Shanghai and Jiaxing, China. Apparently farmers dumped the animals into the water after the pigs became ill, and porcine circovirus was subsequently detected in the in pig carcasses and in the water. Porcine circoviruses are... Read More

Virologia en Español

Tengo el gusto de anunciarles que mi curso de virologia esta ahora disponible en Español.

Este trabajo se realizó bajo la dirección de la Dra. Susana López, virologa del Departamento de Genética del Desarrollo y Fisiología Molecular del Instituto de Biotecnología de la Universidad Nacional A... Read More

Polio-like paralysis in California

Recently a number of children in California have developed a poliomyelitis-like paralysis. The cause of this paralysis is not yet known, and information about the outbreak is scarce. However, acute-flaccid paralysis is not uncommon (California would be expected to report about 75 cases a year, b... Read More

TWiV 339: Herpes and the sashimi plot

Hosts: Vincent RacanielloAlan Dove, and Kathy Spindler Read More

TWiP 89 letters


Robin writes:


Cerebral cysticercosis
.....


(trichinosis?)


Left shift:
This is from the days when dinosaurs roamed the earth:
Manual counters for the differential count had the buttons left to right for neutrophils, bands, eosinophil... Read More

Bacteriophage T4 (video)

This is an accurate visualization of the Bacteriophage T4 based on Cryo-EM datasets of the virus. The scope of the animation is to show the infection process of the T4 into an E. coli cell. All scientific data sets and motion based off of research from Michael Rossmann Laboratory (Purdue Univers... Read More

A novel plate based method for screening DOPA / melanin producing bacteria

Team of researchers guided by Dr.Sarita G Bhat had developed a novel plate based screening technique for DOPA/melanin producing bacteria.Screening was based upon the clear zone formation on a medium suplemented with L-tyrosine.This new approach can be utilized in faster and accurate screening of... Read More

Acute flaccid paralysis of unknown etiology in California

In February 2014 I wrote about children in California who developed a poliomyelitis-like paralysis, also called acute flaccid paralysis or AFP. However, the cause of this paralysis was not known. The CDC has released its study of these cases and concludes “The etiology of AFP with anterior myeli... Read More

Let's declare WAAAR to antimicrobial resistance

We must change how antibiotics are used and adopt proactive strategies, similar to those used to save endangered species. Preservation of the efficacy of antibiotics and to stabilization of antibiotic-susceptible bacterial ecosystems should be global goals.

We urge all of you to participate i... Read More

Virologists plan influenza H7N9 gain of function experiments

A group of virologists lead by Yoshihiro Kawaoka and Ron Fouchier have sent a letter to Nature and Science outlining the experiments they propose to carry out with influenza H7N9 virus. Avian influenza H7N9 virus has caused over 130 human infections in China with 43 fatalities. The source of the... Read More

An unexpected benefit of inactivated poliovirus vaccine

The polio eradication and endgame strategic plan announced by the World Health Organization in 2014 includes at least one dose of inactivated poliovirus vaccine (IPV). Since 1988, when WHO announced the polio eradication plan, it had relied exclusively on the use of oral poliovirus vaccine (OPV)... Read More

Treatment of Ebola virus infection with brincidofovir

The Liberian man who was diagnosed with Ebola virus infection after traveling to Dallas, Texas, was treated with an antiviral drug called brincidofovir. This drug had originally been developed to treat infections with DNA-containing viruses. Why was it used to treat an Ebola virus infection? Read More

Discovery of the Sixth DNA base?

Scientist has described the possible existence of sixth DNA base, the methyl-adenine (mA) this week.

Deoxyribonucleic acid (DNA) is a polymer of nucleotides, which encodes every genetic information of living existence. The entire genetic information are stored within DNA as the form of millio... Read More

Going viral on Science Sunday Hangout on Air

I joined Buddhini Samarasinghe and Scott Lewis on a Science Sunday Hangout on Air to talk about my career in virology: how I came to be interested in viruses, and what goes on in my laboratory. You can find hangouts and more at the ScienceSunday community.


{youtube}WpLH4gRk9gc{/youtub... Read More

Top chefs, artisanal food producers, and microbiologists join forces to explore new tastes and textures

Chefs from top-notch restaurants are reaching out to microbiologists, seeking advice that goes beyond traditional food safety or conventional food-processing concerns. With or without professional scientific advice, some chefs and food producers are doing their own microbiological experiments, s... Read More

Why Sourdough Bread Resists Mold (Press Release)

Sourdough bread resists mold, unlike conventionally leavened bread. Now Michael Gaenzle and colleagues of the University of Alberta, Edmonton, show why. During sourdough production, bacteria convert the linoleic acid in bread flour to a compound that has powerful antifungal activity. The researc... Read More
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