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Colors of Superbug !

Methicillin Resistant Staphylococcus aureus (MRSA) isolated from animals. The organism was grown on seven different agar medium. On blood agar (Centre), it forms small to medium sized colonies surrounded by weak beta-hemolysis. It shows diverse types of color in different chromogenic medium- pin... Read More

MMP #14: A look at several microorganisms involved with electricity.

Host: Jeff Fox with special guests, Gemma Reguera and Geoffrey Gadd.


Gemma Reguera of Michigan State University in East Lansing and Geoffrey Gadd of the University of Dundee in Scotland talk with Jeff Fox about their efforts, to probe some of the electrical properties of materials pro... Read More

TWiEVO 3: Recombination is for the birds

In episode #3 of the new science show This Week in Evolution, Nels and Vincent examine another important driver of evolution: recombination. The results of two papers in which the process is studied in finches and in yeast lead to the unexpected conclusion that recombination evolves more slowly ... Read More

Will you share? Social versus selfish mechanisms affect selective conditions

The previous post mentioned the onset of antibiotic resistance as one of the scarier, if less sensationalist, outbreaks of our time. We generally discuss antibiotic resistance in medically relevant microbes (on this blog and in the news), where resistance means the ability of disease-causing mic... Read More

Rubella virus and birth defects

Amidst the fear surrounding Zika virus, remember that there are over 100,000 children born each year with birth defects caused by infection with rubella virus.

Rubella virus is a member of the Togaviridae family, which also includes chikungunya virus. The genome is a 9.7 kilobase, positive st... Read More

Shiga toxin: no preassembly required

The molecular order of events is important in virulence, and a new paper published in the Journal of Bacteriology looks at the order of events necessary for bacterial toxin delivery to a host cell. Specifically, the authors looked at the assembly of Shiga toxin, produced by Shigella dysenteriae ... Read More

TWiV 403: It's not easy being vaccine

The TWiV team takes on an experimental plant-based poliovirus vaccine, contradictory findings on the efficacy of Flumist, waning protection conferred by Zostavax, and a new adjuvanted subunit zoster vaccine.


Hosts:  Read More

One microbial pathogen 'disguised' as another leads to misdiagnoses

If it looks like a duck and quacks like a duck, it’s likely a duck – so goes the saying that illustrates the simplest explanation is usually the right one. But what about duck decoys used in conjunction with bird calls? Misidentification can be a deadly error – and the same goes for microbes. Mi... Read More

Interview with Dr. Amy Apprill

Amy Apprill is a researcher of Marine Microbiology. Her work focuses on the relation of Bacteria and Archaea to the health and ecology of marine animals. Her interest is on how animal associated microbes reflect the alterations in the surrounding marine environment that may be related to climate... Read More

Zika virus

The rapid spread of Zika virus through the Americas, together with the association of infection with microcephaly and Guillain-Barré syndrome, have propelled this previously ignored virus into the limelight. What is this virus and where did it come from?
Read More

One antibody to neutralize them all: a human IgG1 is effective against multiple subtypes of influenza A virus

The changing weather reminds us that influenza season is around the corner, which means it’s nearly time to get your annual vaccine. This year’s vaccine is updated to protect against influenza A viruses H1N1 + H3N2 and influenza B virus Victoria lineage. These strains are included in vaccine pro... Read More

HIV gets the zinc finger

Because all animal viruses initiate infection by binding to a receptor on the cell surface, this step has long been considered a prime target for antiviral therapy. Unfortunately, drugs that block virus attachment to cells have never shown much promise. Another approach, which is to ablate the r... Read More

Antibodies to dengue virus enhance infection by Zika virus

It has been speculated that the development of neurological disease and fetal abnormalities after Zika virus infection may be due to the presence of antibodies against other flaviruses that enhance disease. In support of this hypothesis, it has been shown that antibodies to dengue virus enhance... Read More

Polio in Nigeria

Polio returns to Nigeria after two years - but it turns out it had never gone away.
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TWiM 101 Letters

Eric writes:


Dear TWIMers,


I am a retired computer programmer and also a free market libertarian. I listened to a recent podcast where the subject of mandatory hand washing by food workers was tossed around. I would like to present a few more of the free marke... Read More

Cyclic-di-GMP takes center stage

How does a single-celled organism ‘know’ how to respond to its environmental conditions? Understanding microbial cell signaling is one way to determine how bacteria will react in a particular setting. In the past decade, researchers have revealed a significant role for cyclic-di-GMP in bacterial... Read More

Researchers hope hybrid compounds can sensitize and inhibit malaria parasites in one blow

Because of its safety, efficacy, and affordability, chloroquine remains the treatment of choice for all Plasmodium species, except in regions with chloroquine-resistant P. falciparum. Chloroquine-resistant protists are treated with combination therapy, which includes artemisinin-derived molecule... Read More

Anti-Vax = Anti-Facts (Please Share)

"Hivi and his team of viruses (Ebola, Pox,..etc) believe they can win the battle, but the Virologists (who are real famous professors) beat them. However, new viruses pop-up, it will be a long battle. This makes the story very interesting and ever so engaging."
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ACKNOWLEDGMEN... Read More

TWiV 400: Harold '400' Varmus, a scientist for all seasons

The TWiV team is together in New York City for a conversation with Nobel Laureate Harold Varmus about his remarkable career in science.


Hosts: Vincent Racaniello Read More

India has been free of polio for three years

Three years ago today, on 13 January 2011, the last case of poliomyelitis was reported in India. This achievement represents a remarkable turnaround for a country where control of the disease had for years been extremely difficult. As recently as 2009 there were 741 confirmed cases of polio caus... Read More
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