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Designer viruses for killing tumor cells

A major goal of viral oncotherapy – the use of viruses to destroy tumors – is to design viruses that kill tumor cells but not normal cells. Two adenoviruses provide perfect examples of how this specificity can be achieved.

Adenovirus CG0070, designed to treat bladder cancer, and adenovirus O... Read More

Happy #MicrobialHalloween From My #Bio350 Students (Plus Some Happy #ParasiticHalloween Wishes)!

I enjoy mixing Hallowe'en with my classes. In this blog post, I show how my microbiology students do exactly that, with humor and style. In addition, my freshman writing students do the same with their course on symbioses and parasitism. Enjoy...and #HappyMicrobialHalloween! Read More

Structure and genome of Zika virus

Group: Group IV ((+) ssRNA)
Family: Flaviviridae
Genus: Flavivirus
Species: Zika virus

Structure of Zika Virus
•The virion is approximately 40 nm in diameter with surface projections that measure roughly 5-10 nm.
•Nucleocapsid is 25-30 nm in diameter surrounded by a host-membrane derive... Read More

My First #LuxArt Class Competition!

In this blog post, I discuss making student designed artwork using bioluminescent bacteria as "paint." As student "buy in" is critical for any course, such fun "creative" approaches act synergistically to improve learning and outcomes. Feel free to vote on your top six images---the students ar... Read More

Virus y pandemias (in Spanish)

Hoy en día, en pleno siglo XXI, ¿puede un virus cambiar el mundo?, ¿puede haber una nueva pandemia mundial? En este libro explicaremos qué es un virus y cómo es la vida de un virus dentro de una célula, veremos qué es una pandemia y hablaremos sobre cómo se originan los nuevos virus de la gripe.... Read More

Microbiology, Creativity, and Extra Credit!

I have long believed that there are many ways for students to learn. In several of my classes, I encourage students to use "creative" approaches to explore course concepts. In the Fall of 2015, here is what my micronauts in my Microbiology course at the University of Puget Sound came up with..... Read More

Prions in plants

Chronic wasting disease is a prion disease of cervids (deer, elk, moose) that is potentially a threat to human health. A role for environmental prion contamination in transmission is supported by the finding that plants can take up prions from the soil and transmit them to animals. Read More

Overexpression of Enterococcus faecalis elr operon protects from phagocytosis

This study investigates how the overexpression of a specific ORF affects the virulence of E. faecalis. Read More

Classic Spotlights: Penicillin for the masses

The Journal of Bacteriology is celebrating its centennial this year – one hundred years of valuable scientific discoveries! To illustrate the wide variety of noteworthy results published over the years, the journal is publishing a Classic Spotlight series, in which experts in the field highlight... Read More

Let It (Microbially) Snow...

I made this video in October of 2015, with my Biology 350 Microbiology students at the University of Puget Sound. A drop of Pseudomonas syringae expressing ice nucleation protein hits supercooled pure water, and fun results. This is the way that Snomax works to commercially generate snow, inci... Read More

Study reveals intestinal bacteria succession during recovery from cholera in Bangladesh

A new study delineates a sequential pattern of changes in the intestinal microbial population of patients recovering from cholera in Bangladesh, findings that may point to ways of speeding recovery from the dangerous diarrheal disease. The report also finds what appear to be consistent differenc... Read More

Sushi protects mosquitoes from lethal virus infections

As far as I know, mosquitoes do not eat sushi. But mosquito cells have proteins with sushi repeat domains, and these proteins protect the brain from lethal virus infections. Read More

Surprise in Lab

Unknown fungi isolated from soil sample.I would like to have inputs from the Mycologist in the forum about this fungal colony,its identification,name,species and genus? Read More

The Bacteria Song by the Science Pirates

Science Pirates Songs presents the Bacteria Song by New Mexico State University 2003. These animated songs are from the adventure learning game, 'Science Pirates: The Curse of Brownbeard', which guide middle school students through concepts in both science and food safety. Read More

Freshman Biology Creative Projects

I am a big believer that different pedagogical approaches can "reach" different students. In most of my classes, I give students an optional assignment: come up with a creative project that explores some aspect of class. This takes several steps. First, I make the students come up with an ide... Read More

Stilton Cheese, Alexis de Toqueville, and turning ASM into the Tesla of Scientific Societies

“Stefano, you seem like a smart person. Can I ask you why you decided to take a job with a scientific society?” I had just helped myself to a slice of a very sharp Stilton cheese, after a wonderful dinner supported by wonderful wine. All of a sudden the Stilton seemed even sharper. The question ... Read More

MMP #12: Hydrogen from ground rocks can furnish microbial ecosystems with energy to drive growth.

Host: Jeff Fox with special guest, Jon Telling.


Jon Telling of Bristol University in Bristol, United Kingdom talks with Jeff Fox about his findings suggesting that the grinding of glaciers over rocks can liberate hydrogen, which, in turn, drives the growth of methanogens within microb... Read More

MMP #3: Smallpox and the Native Americans with Paul Kelton

Host: Jeff Fox Read More

Animals (and Plants) in a Microbial World

In this blog post (and fourth "Mu-Tube" video), I explore the idea that all animals and plants have evolved as part of a microbial world, and thus microbes are a part of us. I do this by having my undergraduate students explore two recently publications by Dr. Margaret McFall-Ngai,and recording... Read More

A Bornavirus / host interactome

A referenced interactome of host genes and proteins affected by the Bornavirus. KEGG pathways of the host arm of the interactome are also linked from the interactome page. If you have any data to add please use the email link on the page and I will update the various pathways. Read More

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