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Smartphone microscope turns microbiology into game time

A new 3-D printed, easily assembled smartphone microscope developed at Stanford University turns microbiology into game time. The device allows kids to play games or make more serious observations with miniature light-seeking microbes called Euglena.

When it’s assembled, it has a platform for... Read More

SHIFTS IN MICROBIAL COMMUNITIES DUE TO CLIMATE CHANGE AFFECT ALL ECOSYSTEMS

“As we experience unprecedented environmental impacts from climate change, microbes rapidly adapt to their surrounding conditions faster than other organisms. Because microbes control biogeochemical cycling of elements essential for life, this impacts every ecosystem on earth. In addition, these... Read More

ASM Members Deliver a Landslide Endorsement for Governance Change - Part 2

In my previous posting (Part 1), I reflected on the historical change of the new ASM governance. Here I would like to highlight some key issues that I see facing ASM and its new governance structure. This is not a prescriptive list, but rather a list of goals or, if you prefer, a straw man for ... Read More

Advancing Phage Therapy

New research conducted at the University of Miami in Coral Gables, Florida and the National Cancer Institute, in Bethesda, Maryland demonstrate that a subset of bacteriophages, dubbed “superspreaders,” potentially play a major role in transmitting antimicrobial resistance. The research, describe... Read More

Global Warming Damages Symbiotic Organisms

Ten years ago, Takema Fukatsu, PhD, prime senior researcher and leader, National Institute of Advanced Industrial Science and Technology (AIST) in Japan, was invited to Kyoto University as a symposium speaker of a meeting organized by Kenji Fujisaki, PhD, a researcher in the University's Graduat... Read More

You Say Auto-phagy, I Say Au-toph-agy: Let's Call the Whole Thing Awfully Amazing

The Nobel Prize for Medicine this year went to Dr. Yoshinori Ohsumi of the Tokyo Institute for Technology for his work on autophagy, the process of digesting unneeded or damaged cellular components. This process plays a role in many central cellular activities, with applications ranging from gen... Read More

"What will change in Clinical Microbiology Laboratories by 2050?"

If you are lucky enough to be still alive and working in 2050... How might the clinical microbiology laboratory have changed by that time? Nobody can accurately predict the future, but here are my personal thoughts... Read More

Evidence for the Biosynthesis of Bryostatins by the Bacterial Symbiont “Candidatus Endobugula sertula” of the BryozoanBugula neritina

I thought this area of bryostatin study might spark your interest. It has the potential to treat cancer and Alzheimer’s disease. Whether looking at the way the compound is formed in nature or the challenge of synthesizing the compound is fascinating.

https://www.google.com/search?q=bryozoan+B... Read More

Moleculo Facilitates Assembly and Binning from Soil

Soil microorganisms carry out key processes for life on our planet, including cycling of carbon and other nutrients and supporting growth of plants. However, there is poor molecular-level understanding of their functional roles in ecosystem stability and responses to environmental perturbations.... Read More

Influenza Viruses by James McSharry, PhD

In this ASM Virtual Lecture Dr. James McSharry, Professor Emeritus, Albany Medical College, describes the structure of the influenza viruses, types of human influenza viruses and their replication in cells, licensed influenza drugs, current influenza vaccines, and the future of influenza vacci... Read More

S. mutants mutation increases fluoride resistance


Microbes are excellent at adapting to stressful situations, which is part of the reason antibiotic resistance is a problem today. Constant exposure to antimicrobials such as triclosan have selected for resistant strains, rendering the compound ineffective. This is why the FDA recently banned t... Read More

Seeking understanding of the bacterial sec system

How do bacterial proteins destined for export move from inside to outside the cell? As mBiosphere readers may know, there are a number of secretion systems that bacteria use to move materials from inside the cell to outside the cell. Some of these systems, such as the Sec secretion system, are c... Read More

Researchers Discover Antifungal Agent From Pathogen Box Project

Researchers report they have used the Pathogen Box to identify a novel, highly potent antifungal agent with activity against two of the most common fungal pathogens of humans. Read More

Virus Watch: Counting Viruses

In this episode of Virus Watch, I show how to do my favorite assay in all of virology - the plaque assay.

Read More

History Lesson - The Day the US Senate Tried to Change the Name of Salmonella

In an attempt to preserve and defend the good name of the salmon fished in his state, Senator Warren Magnuson (D-WA), introduced in 1969 a bill in the US Senate pro­po­sing to change the name of Salmonella  to the more in­oc­cu­ous sounding Sanella. In some circles it may seem com­for­ting to th... Read More

Tell Us Your Story about You and Your Proteins

We would like to know the experience when you work with your proteins (recombinant protein, native protein, lysate etc.), no matter it is success or failure. Did you get on well with the protein or still “fight” with it? Tell us your story. But, no, no, no, we don’t want to hear your presentatio... Read More

An Unseen Step to Diagnoses: Specimen Handling

Collecting, transporting, and storing patient specimens plays a major role in infection diagnoses. ASM provides a number of resources regarding best practices and the latest research regarding specimen collection! Read More

MetaPalette: a k-mer Painting Approach for Metagenomic Taxonomic Profiling and Quantification of Novel Strain Variation

Taxonomic profiling is a challenging first step when analyzing a metagenomic sample. This work presents a method that facilitates fine-scale characterization of the presence, abundance, and evolutionary relatedness of organisms present in a given sample but absent from the training database. We ... Read More

Global warming collapses symbiotic gut bacteria, killing host insects

A new study shows that when heat-susceptible bacteria living symbiotically in the guts of insects are exposed to increased temperatures, both the bacteria and the insect are negatively impacted and can die. The study, reported online this week in the journal mBio®, illustrates another way globa... Read More

Testing staphylococci for oxacillin resistance - why is it so complicated?

Be honest – do the cases in the lefthand table make you break into hives? It’s not an uncommon response! S. aureus is a sneaky bacterium, throwing susceptibility curve-balls like those to the left on a regular basis. Not to mention the non-aureus staphylococci, which we are now routinely identif... Read More
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