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TWiM 105 Letters


David writes:


Greetings podcast team,


I'm a long-time listener to TWIM and TWIV and if I had a longer commute I would get TWIP in the mix too. Only so many hours in the week!


I am a research tech in Portland Oregon, where our dry mild winter has g... Read More

Scientists, share your Zika virus reagents!

Today I learned that a number of investigators refuse to share their samples of Zika virus with other laboratories.

There are countless stories about scientists not sharing reagents because they want to be the first to make a discovery. This behavior allows them to publish first, secure more ... Read More

MMP #10: Examining the gut microbiota of American Indians of Cheyenne and Arapaho ancestry.

Host: Jeff Fox with special guests, Cecil M. Lewis, Jr. and Krithivasan Sankaranarayanan.


Lewis and Krithivasan Sankaranarayanan—“Krithi”-- both fro... Read More

Changing the mindset of a pathogen-based vaccine

It’s hard to turn on the news at the moment and not hear about the latest emerging disease, Zika. The filovirus joins a cadre of infectious diseases spread by arthropod vectors – meaning the disease is passed between infected individuals via insect bites. A long list of microbes are spread this ... Read More

Foot and mouth disease virus: a global threat to agriculture

An important and sometimes overlooked issue of infrastructure is food security. American agriculture and related industries represent $1.5 trillion U.S. dollars and 17% of U.S. jobs. These workers provide the meat, eggs, dairy, and produce that many take for granted will end up on grocery shelve... Read More

TWiM 125 Letters

Inspired by William:


Dear TWiMers;
Greetings from Berkeley where miracle March (water-wise) was perhaps half a miracle, but that is definitely better than none. At least we will not run out of water this summer.


I found this quasi-synthetic biology result... Read More

Nonpathogenic viruses transferred during fecal transplants

Fecal transplants are increasingly being used for refractory Clostridium difficile and other gastrointestinal disorders. While fecal donors are screened for various infectious diseases, it is unclear whether viruses can in fact be transmitted during fecal transplants. Now a new study shows that ... Read More

Identifying milk components that promote a healthy infant microbiome

Breast milk provides an inexpensive, nutrient-filled source of food for babies. Because of this, the American Academy of Pediatrics and the WHO recommend new mothers to exclusively breast feed their babies for the first six months of life, and continue up to two years (supplemented with other fo... Read More

TWiV 374: Discordance in B

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

MMP #9: Customizing phage by swapping tail genes to target specific pathogens

Host: Jeff Fox with special guest, Timothy Lu.


Lu, an Associate Professor of Biological Engineering and Electrical Engineering and Computer Science at Massachusetts Institute of Technology in Cambridge, Massachuse... Read More

TWiM 127 Letters

Stefan writes:


Just discovered this nice episode.
Well made and nicely discussed comment on our pack-hunting paper; quick reply to the question what would happen if you add one single amoebae: it would multiply and a clonal pack would do the same thing as observe... Read More

New bat gammaherpesvirus may help understand bats' role in zoonoses

Many emerging viruses (such as SARS-CoV, Ebola virus, and the Henipavirus genus) are thought to have zoonotic reservoirs in the regional bat populations. Bats offer a threat to spreading these viruses because their flight capacity makes them readily mobile. Also, there are a whole lot of them: w... Read More

TWiV 385: Failure

Hosts: Vincent Racaniello and Dickson Despommier


Guest: Stuart Firestein Read More

TWiEVO 1: When (scientific) worlds collide

Nels and Vincent launch a new podcast on evolution, This Week in Evolution (TWiEVO) and start by discussing how the field has changed through recent mergers of evolutionary and experimental biology in the post-genome era. Read More

TWiV 381: Add viruses and Zimmer

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiV 352: Science art with Michele Banks

Host: Vincent Racaniello


Guest: Michele Banks


Vincent meets up with Michele Banks in Wash... Read More

E. coli, Salmonella, and Norovirus - oh my!

This upcoming Monday, Chipotle restaurants across the country will close as its employees discuss food safety and safe food handling. The restaurant was in the news throughout the last half of 2015, beginning with an outbreak of E. coli in Seattle (which was kept secret!), followed by another E.... Read More

Top secret, viruses with RNA genomes!

Today it is well known that viruses may contain DNA (poxvirus, mimivirus) or RNA (influenza virus, Zika virus), but for many years it was thought that genomes were only made of DNA. The surprise at finding only RNA in a virus is plainly evident in a 1953 letter from Harriett Ephrussi-Taylor to J... Read More

TWiV 386: The dolphins did it

Hosts: Vincent RacanielloRich Condit, and  Read More

Shelves and mentors

When I became Peter Palese’s first Ph.D. student in 1976, his laboratory at Mt. Sinai School of Medicine in New York City was in dire need of shelves. The laboratory benches (pictured) had no room for storing the many bottles of reagents that I was beginning to generate. Read More
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