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Getting Started with MicrobeWorld

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A virus-like particle vaccine against RSV is safe and effective in mice

Pneumonia remains a serious worldwide problem, especially among the young, elderly, and immunocompromised. Over 900,000 children die each year due to the disease, and respiratory syncytial virus (RSV) is the most common viral cause (Streptococcus pneumoniae and Haemophilus influenzae type b bein... Read More

Induction of Acinetobacter baumannii natural competence

Bacteria acquire and spread genetic information through several means. Some bacteria form a long, thin tube called a pilus, mediating transfer of DNA by direct cell-to-cell contact, in a process known as conjugation. Some bacterial take up environmental DNA and incorporate it into their existing... Read More

SUBMIT MICROBE ABSTRACTS NOW: ONE IN FIVE ACCEPTED WILL BE ORAL PRESENTATION

The call for abstracts is now open for Microbe 2017, the premier microbiology conference hosted by the American Society for Microbiology. This is your opportunity to submit your important research in the microbial sciences to the largest scientific audience, with a 50% higher chance of presentin... Read More

TWiV 419: The selfless gene

The TWiVrific gang reveal how integration of a virophage into the nuclear genome of a marine protozoan enhances host survival after infection with a giant virus.


Hosts: Vincent Racaniello Read More

Meta-analysis of urine pre-analytic practice reveals need for rigorous studies

Evidence-based medicine is the approach used by doctors to make rational clinical decisions based on rigorous, well-controlled studies. By minimizing hunches, gut feelings, and anecdotal evidence, physicians and patients can follow recommendations that are most likely to have a positive outcome.... Read More

How E. coli could help tackle those sweet cravings

The study researchers found that placing a small, detoxified amount of E. coli in the guts of mice led to an increase in levels of leptin - known as the "satiety hormone."

Within 7 days of the increase, the number of sweet taste receptors on the rodents' tongues reduced, diminishing their ap... Read More

Enhanced virus transduction may lead to more effective gene therapy

A benefit of the voluminous wealth of research produced is that it allows us to stand on the shoulders of giants – we can take advantage of established facts, tools, and datasets. This may mean using a mutant library to find genes in your organism that are important for the process you study; ac... Read More

Two birds with one stone: E. faecium cotransfers drug resistance determinants by homologous recombination

The Gram-positive bacterium Enterococcus faecium is a member of the ESKAPE pathogens for which drug resistance has been a growing problem. How E. faecium becomes drug resistant has been a long-standing question, and is the focus of a new study now available in Antimicrobial Agents and Chemothera... Read More

And they're off! An overview of ASM resources on Olympic-related infectious disease reports

The opening ceremony for the Summer Olympics 2016 will be held this Friday, marking the onset of two weeks of competition between the world’s best athletes. The world has been focused on Brazil and its preparedness – not only for the infrastructure required for the games, but also for any potent... Read More

Diversity and Activity of Communities Inhabiting Plastic Debris in the North Pacific Gyre

Marine plastic debris is a growing concern that has captured the general public’s attention. While the negative impacts of plastic debris on oceanic macrobiota, including mammals and birds, are well documented, little is known about its influence on smaller marine residents, including microbes t... Read More

A Microbial Ocean Feast: Who Ate What?

Single-celled organisms called bacterioplankton spend their lives drifting in open ocean, visible to the naked eye only en masse. But don't be fooled by their slight size: These minuscule critters play a hefty role in the carbon cycle. Heterotrophic microbes, by some estimates, process half of t... Read More

Demystifying secondary bacterial pneumonia

In some individuals, an influenza A virus infection can cause asymptomatic Staphylococcus aureus (S. aureus) to travel to the lungs where it can trigger severe, sometimes deadly, secondary pneumonia. S. aureus is one of the most common causes of secondary bacterial pneumonia in cases of seasonal... Read More

Boston subway system covered in microbes, but they're not harmful

As part of its Microbiology of the Built Environment initiative, the Alfred P. Sloan Foundation started funding projects a few years ago that touched on the interaction of microbiology with architecture, buildings or, in the case of Curtis Huttenhower, PhD, an associate professor of computationa... Read More

BacterioFiles 274 - Proteobacteria Purify Piscine Pee

This episode: Bacteria in the gills of fish help break down their metabolic wastes before they reach toxic levels!


(7.4 MB, 8.1 minutes)


Show notes: 


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TWiM #142: A membrane-thickness caliper

Vincent, Elio and Michele wind up a year of microbial podcasts with a story about the lack of resistance to a crop antifungal compound, and how a bacterium uses a molecular caliper to measure membrane thickness.


Hosts:  Read More

MERS research yields surprising finding

In 2015, an unexpectedly large outbreak of Middle East Respiratory Syndrome coronavirus (MERS-CoV) in South Korea had a disastrous impact on the whole country and highlighted scientists limited knowledge of this virus. Now, new research into this outbreak has revealed some very surprising findin... Read More

Microbial responses to land management practices

Microbial communities are essential drivers of soil functional processes such as nitrification and heterotrophic respiration. Although there is initial evidence revealing the importance of soil type in shaping microbial communities, there has been no in-depth, comprehensive survey to robustly es... Read More

Additives to boost vaccine responses not sufficient to protect obese mice from influenza

At St. Jude Children’s Research Hospital in Memphis, Tenn., scientist Stacey Schultz-Cherry has been studying the impact of obesity on influenza severity.

“We saw during the 2009 flu pandemic that there’s an epidemiological link between people getting severe flu and being obese,” says Schultz... Read More

BacterioFiles 283 - Phages Furnish Photosynthetic Fortifications

This episode: Viruses infecting photosynthetic bacteria could transfer immunity to other viruses between their hosts!


(6.8 MB, 7.4 minutes)


Show notes: 


Read More

A Microbial Death Star

Star Wars – an epic story of war between the forces of good and evil in a galaxy far, far away. The Death Star – the ultimate weapon of destruction. The story is science fiction, but it could be considered an analogy for the constant battle between our immune system and microbial pathogens. Beli... Read More
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