The TWiPniks docs solve the case of the Female from Peru with Epistaxis, and discuss the effect of community deworming on immunosuppression.
It has been speculated that the development of neurological disease and fetal abnormalities after Zika virus infection may be due to the presence of antibodies against other flaviruses that enhance disease. In support of this hypothesis, it has been shown that antibodies to dengue virus enhance... Read More
The molecular order of events is important in virulence, and a new paper published in the Journal of Bacteriology looks at the order of events necessary for bacterial toxin delivery to a host cell. Specifically, the authors looked at the assembly of Shiga toxin, produced by Shigella dysenteriae ... Read More
In this new video episode of Virus Watch, you'll see how the Zika virus particle is built, and how it binds to an antibody that blocks infection. All in gorgeous three dimensional views provided by recent structure studies. Read More
"Hivi and his team of viruses (Ebola, Pox,..etc) believe they can win the battle, but the Virologists (who are real famous professors) beat them. However, new viruses pop-up, it will be a long battle. This makes the story very interesting and ever so engaging."
ACKNOWLEDGMEN... Read More
For the article letter about microbial batteries, I think CV refers to Capacitance times Voltage, which is stored charge. In electronics, current is abbreviated I not C.
The claim in the letter got me thinking about microbial batteries and I wrote ... Read More
One of the most dangerous places for an infection to occur is in the bloodstream. Septicemia, when microbes are present in the blood, not only allows bacteria access to other internal organs through the highway of our circulatory system, but also can cause a massive inflammatory response, leadin... Read More
Mapping and identifying all the microbes across New York City is no small feat. Just ask Jane Carlton. About three years ago, Carlton, director of the Center for Genomics and Systems Biology, and professor of biology, at New York University and colleagues won an NYU grand challenge grant for the... Read More
We’ve previously covered the importance of diagnostics in disease control and treatment. This is vital to controlling disease progression and transmission, but epidemiology studies can’t always show how a disease progresses or transmits. This is where scientists need a well-characterized animal ... Read More
The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids.
Hosts: Read More
The TWiVome reveal the first eukaryotic genes found in a bacteriophage of Wolbachia, and how DNA tumor virus oncogenes antagonize sensing of cytoplasmic DNA by the cell.
Because of its safety, efficacy, and affordability, chloroquine remains the treatment of choice for all Plasmodium species, except in regions with chloroquine-resistant P. falciparum. Chloroquine-resistant protists are treated with combination therapy, which includes artemisinin-derived molecule... Read More
Virus Watch is a new weekly video series that explores the amazing world of viruses. This week: the latest research on Zika virus, including finding virus in Brazilian monkeys, dengue antibodies helping Zika virus infection, and brain organoids to study how Zika virus causes microcephaly. Read More
The TWiVnauts present another example of an infectious but replication incompetent vaccine, an insect specific arborvirus bearing chikungunya virus structural proteins.
Clostridium difficile is a dangerous superbug. Infections with this bacterium can cause life-threatening diarrhea, and they are most likely to affect the elderly or people with health problems who spend a lot of time in hospitals (where C. difficile flourishes). The Centers for Disease Control a... Read More
If it looks like a duck and quacks like a duck, it’s likely a duck – so goes the saying that illustrates the simplest explanation is usually the right one. But what about duck decoys used in conjunction with bird calls? Misidentification can be a deadly error – and the same goes for microbes. Mi... Read More
I teach Microbiology at the University of Puget Sound every fall semester. The swiftly changing field of microbiology has depth and breath...and I was interested to learn what my students thought of the topic at the beginning of the first day of class. We will revisit this subject at the end o... Read More
I was asked to write a commentary for the Proceedings of the National Academy of Sciences to accompany an article entitled SARS-like WIV1-CoV poised for human emergence. I’d like to explain why I wrote it and why I spent the last five paragraphs railing against regulating gain-of-function experi... Read More
Several papers published in Genome Announcements recently describe the sequences of new Zika virus isolates. Scientists have known the genomic sequence of at least one Zika virus isolate since 2007, but continue to publish newly isolated strains. What is the importance of these additional sequen... Read More
Jennifer joins Vincent, Elio, and Michael to talk about the work of her laboratory on how a respiratory virus enhances bacterial growth by dysregulating nutritional immunity.