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Retroviral influence on human embryonic development

About eight percent of human DNA is viral: it consists of retroviral genomes produced by infections that occurred many years ago. These endogenous retroviruses are passed from parent to child in our DNA. Some of these viral genomes are activated for a brief time during human embryogenesis, sugge... Read More

Mineralization of sand particles boosts microbial water filtration

Mineral coatings on sand particles actually encourage microbial activity in the rapid sand filters that are used to treat groundwater for drinking, according to a paper published ahead of print in Applied and Environmental Microbiology. These findings resoundingly refute, for the first time, the... Read More

Magical Monsoon:rAiNs and Geosmin

A Geosmin Story:
A Musty / Muddy smell - the earthy odour after a heavy spatter of rain is aesthetic to senses.
A poet sitting in such ambiance lets his thoughts to wander randomly and comes out with a sweet piece of write up.
An Artist can do wonders on his canvas flowing with the mood.
Man... Read More

Immunological Reaction of Poison Ivy - Explained Through Poetry

Immunology Explained Through Poetry - What happens when one touches a poison ivy?

Enjoy!

Billy was at summer camp,
And wanted to feel like a champ,
So he searched for a flower,
That would stop Susie’s glower,
But found poison ivy instead.

While Billy was later playing,
He had no i... Read More

Should you consider attending ASM 2015 this spring?

The general program for the 2015 American Society of Microbiology meeting in New Orleans is out, and registration is now open. The sessions look incredible, and I've listed them below as I imagine they might resonate with many of the readers of this blog. The bolded sessions look particularly in... Read More

Livestock-Associated Staphylococcus aureus: The United States Experience

Animal associated S. aureus are distinct from human strains but some recent studies suggested the human infection caused by animal origin strain of MRSA. Extensive and unregulated use of antibiotic in animal husbandry might be one of the causes for development of multidrug resistant strain. Tran... Read More

Viral genomes in 700 year old caribou scat

Recovering viral genomes from ancient specimens can provide information about viral evolution, but not many old nucleic acids have been identified. A study of 700 year old caribou feces reveals that viruses can be protected for long periods of time – under the right conditions. Read More

BDP FL maleimide - BODIPY analog - fluorescent labeling of proteins

BDP FL maleimide
http://www.lumiprobe.com/p/bodipy-fl-maleimide

BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy. BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar... Read More

My First Radio Interview About Teaching, Research, and Microbial Supremacy...

The great folks at "The People Behind the Science" interviewed me over Skype in late July, and the interview has just been released as a podcast. I discuss my path through science, my thoughts on teaching, research at undergraduate institution, and how to motivate and inspire students to strive... Read More

How influenza virus infection might lead to gastrointestinal symptoms

Human influenza viruses replicate almost exclusively in the respiratory tract, yet infected individuals may also have gastrointestinal symptoms such as vomiting and diarrhea. In mice, intestinal injury occurs in the absence of viral replication, and is a consequence of viral depletion of the gut... Read More

Surprise in Lab

Unknown fungi isolated from soil sample.I would like to have inputs from the Mycologist in the forum about this fungal colony,its identification,name,species and genus? Read More

Supercomputer Modelling of a Complete Human Viral Pathogen: Poliovirus (Polio virus)

Follow the reconstruction and simulation of poliovirus using the BlueGene/Q supercomputer at the Victorian Life Sciences Computation Initiative. The poliovirus model is being used as a basis for understanding antiviral drugs, virus infection and helps us to learn how to model related viruses suc... Read More

TWiP 86 letters

Jan writes:


Dear Doctors


This one is a bit more tricky; both Giardia and Cryptosporidium are possible. The symptoms are more those of Cryptosporidium, so that would be my semi-educated guess. Most of that education comes through you, with some help of some CDC... Read More

Long-term effects of Ebolavirus infection

The thousands of survivors of the Ebolavirus outbreak in western Africa – more than at any other time – are fortunate to have survived the disease. However, their health problems are not behind them. A new study shows that the survivors of Ebolavirus have long-term sequelae more than 2 years aft... Read More

Happy Microbial Valentines Day---In Words of Living Light!

In this short blog post, I "write" on Petri dishes with bioluminescent bacteria to create words and poems in "living light." I also write a haiku to quorum sensing in the same style! Read More

The Black Sheep of Microbe Family

Pleasing view-Microvista. Read More

Viruses in the extreme

Many microbes live in extreme environments, encountering conditions that are very hot, very cold, highly acidic, or very salty. The viruses that infect such microbes must also be able to retain infectivity in extreme conditions. How do they do it?

Clues come from the observations that the gen... Read More

A protein platform for priming

The enzymes that make copies of the DNA or RNA genomes of viruses – nucleic acid polymerases – can be placed into two broad categories depending on whether or not they require a primer, a short piece of DNA or RNA, to get going. The structure of the primer-independent RNA polymerase of hepatitis... Read More

Forecasting future infectious disease outbreaks

(Millbrook, NY) Machine learning can pinpoint rodent species that harbor diseases and geographic hotspots vulnerable to new parasites and pathogens. So reports a new study in the Proceedings of the National Academy of Sciences led by Barbara A. Han, a disease ecologist at the Cary Institute of E... Read More

New Drugs May Come from Microbes in Our Guts

Plants and Microorganisms are the major sources of drugs till date. Most of these "natural products" come from a few genera of soil and marine bacteria that have long been known for their prolific chemistry. The classical process of discovering drugs from microorganisms have two drawbacks- it is... Read More
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