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Vincent Racaniello: Earth’s Virology Professor

A new blog written by undergraduate students from the School of Genetics and Microbiology, Trinity College Dublin features Vincent Racaniello, PhD, host of This Week in Virology.

"Most students studying science at university will inevitably become familiar with the names and works of a wide r... Read More

Zika virus infection of the nervous system

Evidence is mounting that Zika virus is neurotropic (able to infect cells of the nervous system) and neurovirulent (causes disease of the nervous system) in humans. Read More

TWiV 416: Scattered seeds dormant

The multi-dimensional TWiV-brane brings you the entries in the haiku/limerick contest, and explain how a giant virus infects a host within another host (it has to do with predators!).


Hosts:  Read More

TWiV 404: Not found

From the twiVivants, follow up on FluMist and Zoster vaccines, Zika virus update, and isolation of a multicomponent animal virus from mosquitoes.


Hosts: Vincent Racaniello Read More

Polio in Nigeria

Polio returns to Nigeria after two years - but it turns out it had never gone away.
Read More

mSystems video introduction, or: The tl;dr version for ADAGE-based integration of gene expression datasets

We at mBiosphere know you are busy, reader! With various gels, analyses, programs, and classes to run, not to mention reports, abstracts, and grants to write, we know there are many demands made on our readers’ time (plus, dinner to plan, laundry to fold, the dog to walk...wait! Don't go! You ha... Read More

BacterioFiles 267 - Crust Color Cooks Communities

This episode: Cyanobacteria in biocrusts produce pigments that heat their surroundings up to 10 degrees hotter!


(7 MB, 7.6 minutes)


Show notes: 
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Antibodies to dengue virus enhance infection by Zika virus

It has been speculated that the development of neurological disease and fetal abnormalities after Zika virus infection may be due to the presence of antibodies against other flaviruses that enhance disease. In support of this hypothesis, it has been shown that antibodies to dengue virus enhance... Read More

Shiga toxin: no preassembly required

The molecular order of events is important in virulence, and a new paper published in the Journal of Bacteriology looks at the order of events necessary for bacterial toxin delivery to a host cell. Specifically, the authors looked at the assembly of Shiga toxin, produced by Shigella dysenteriae ... Read More

Virus Watch: Building Zika Virus

In this new video episode of Virus Watch, you'll see how the Zika virus particle is built, and how it binds to an antibody that blocks infection. All in gorgeous three dimensional views provided by recent structure studies. Read More

TWiP 122: If the thunder don't get you, the lightning will

The TWiPniks docs solve the case of the Female from Peru with Epistaxis, and discuss the effect of community deworming on immunosuppression.


Hosts: Vincent Racaniello Read More

Anti-Vax = Anti-Facts (Please Share)

"Hivi and his team of viruses (Ebola, Pox,..etc) believe they can win the battle, but the Virologists (who are real famous professors) beat them. However, new viruses pop-up, it will be a long battle. This makes the story very interesting and ever so engaging."
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ACKNOWLEDGMEN... Read More

Diagnostic guidelines for bloodstream infections aim to shorten time to accurate therapy

One of the most dangerous places for an infection to occur is in the bloodstream. Septicemia, when microbes are present in the blood, not only allows bacteria access to other internal organs through the highway of our circulatory system, but also can cause a massive inflammatory response, leadin... Read More

TWiM 141 Letters

Tom writes:


For the article letter about microbial batteries, I think CV refers to Capacitance times Voltage, which is stored charge. In electronics, current is abbreviated I not C.


The claim in the letter got me thinking about microbial batteries and I wrote ... Read More

Microbes Found on New York City ATM Keypads Mostly from Human Skin, Food

Mapping and identifying all the microbes across New York City is no small feat. Just ask Jane Carlton. About three years ago, Carlton, director of the Center for Genomics and Systems Biology, and professor of biology, at New York University and colleagues won an NYU grand challenge grant for the... Read More

Ferreting out an improved Ebola animal model

We’ve previously covered the importance of diagnostics in disease control and treatment. This is vital to controlling disease progression and transmission, but epidemiology studies can’t always show how a disease progresses or transmits. This is where scientists need a well-characterized animal ... Read More

TWiV 406: Pow, right in the enteroids!

The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids.


Hosts:  Read More

Researchers hope hybrid compounds can sensitize and inhibit malaria parasites in one blow

Because of its safety, efficacy, and affordability, chloroquine remains the treatment of choice for all Plasmodium species, except in regions with chloroquine-resistant P. falciparum. Chloroquine-resistant protists are treated with combination therapy, which includes artemisinin-derived molecule... Read More

Virus Watch: Zika Edition

Virus Watch is a new weekly video series that explores the amazing world of viruses. This week: the latest research on Zika virus, including finding virus in Brazilian monkeys, dengue antibodies helping Zika virus infection, and brain organoids to study how Zika virus causes microcephaly. Read More

An achilles heel for Clostridium difficile infections?

Clostridium difficile is a dangerous superbug. Infections with this bacterium can cause life-threatening diarrhea, and they are most likely to affect the elderly or people with health problems who spend a lot of time in hospitals (where C. difficile flourishes). The Centers for Disease Control a... Read More
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