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Getting Started with MicrobeWorld

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BacterioFiles 250 - Bacteria Boost Berry Borer Beetle Babies

This episode: Gut bacteria make it possible for coffee berry borer beetles to live entirely on caffeine-rich food!


(6.9 MB, 7.5 minutes)


Show notes: 
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TWiM #130: Interkingdom interactions at ASM Microbe

The TWiMers get together at ASM Microbe 2016 in Boston to speak with David and Vanessa to talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.


Hosts: Read More

BacterioFiles 253 - Probiotics Promote Protective Pathway

This episode: In mice and fruit flies, Lactobacillus species induce gut cells to protect themselves from reactive oxygen compounds!


(8.2 MB, 8.9 minutes)


Show notes: 
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BacterioFiles 258 - Transformed Toxin Translocates Treatments

This episode: Bacterial toxins could be modified to deliver life-saving proteins into neurons!


(11.1 MB, 12.1 minutes)


Show notes: 
Journal Paper:

Chen C, Przedpelski A, Tepp WH, Pellett S, Johnson EA, Barbieri JT. 2015.... Read More

BacterioFiles 256 - Virus Versus Virus

This episode: Viruses can cause host cells to inhibit other viruses!


(8 MB, 8.75 minutes)


Show notes: 
Journal Paper:

Chiba S, Suzuki N. 2015. Highly act... Read More

BacterioFiles 254 - Clostridium Consolidates Combustibles Conversion

This episode: Engineering bacteria to convert cellulose directly into useful biofuels and chemicals can be tricky!


(13.9 MB, 15.2 minutes)


Show notes: 
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BacterioFiles 251 - Mycophagous Myrmicinae Mutualist Microbes

This episode: Gut bacteria seem to help ants with very restrictive diets flourish more!


(10.6 MB, 11.5 minutes)


Show notes: 
Journal Paper


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BacterioFiles 255 - Colonizer Controls Carrier Cultivation

This episode: Some bacteria seem to cause slime mold amoebas to carry around other bacteria for food!


(12.4 MB, 13.5 minutes)


Show notes: 
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TWiP 110: Malaria at the Bronx Zoo

The TWiP trio visit the Bronx Zoo where Paul solves the case of the Four Year Old with Pulmonary Edema, and talks about his career as the Chief Veterinarian and Director of the Zoological Health program for the Wildlife Conservation Society.


Hosts:  Read More

BacterioFiles 249 - Spores Survive Spaceship Scorching

This episode: Bacterial spores can survive atmospheric entry on an artificial meteorite!


(10.7 MB, 11.25 minutes)


Show notes: 
J... Read More

TWiM 131: Mice behaving badly

Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.


Hosts: Vinc... Read More

TWiM #127: Subway Snowblowers and Men in Black

The TWiM team explores microbes in snowblower vents on the ocean floor, and cleavage of antibody molecules by a Mycoplasma protease.


Image (right): Photograph of the ‘Subway’ snowblower vent on the sea floor at Axial Seamount, Juan de Fuca Ridge. Visible are white ‘snow’ in the vent a... Read More

TWiM #128: A moonlighting phage protein

A eukaryote without a mitochondrion, and using a phage enzyme to eliminate intracellular bacteria are two topics discussed by the TWiMers on this episode.


Image (right): An entry in the ASM Agar Art Contest which bears an uncanny resemblance to one of the TWiM hosts.


Host... Read More

BacterioFiles 252 - Small Cells Supervise Circadian Cycles

This episode: In mice, high-fat diets affect their gut microbes, which in turn disrupts their circadian cycles and metabolic health!


(8.6 MB, 9.35 minutes)


Show notes: 
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TWiM #129: Dried and wrinkled, smooth and mucoid

The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.


Image (right): Etest used to determin... Read More

TWiM #133: Right under our noses

Insight into the biology of rhinovirus C from cryo-electron microscopy, and a novel antibiotic from a commensal bacterium that grows in the human nose, from the doctors of TWiM.


Hosts: Vincent Racaniello, Elio Schaechter, an... Read More

TWiP 109: Blame it on Mother

Daniel and Vincent solve the case of the Truck Driver from India, discuss why parasites resistant to an antimalarial drug are not transmitted by mosquitoes, and introduce Paul who presents a new case study.


Hosts:  Read More

BacterioFiles 261 - Pilfered Parasitoid Proteins Protect Prey

This episode: Viruses domesticated by parasitoid wasps have transferred wasp genes to caterpillar victims, allowing them to survive deadly infections from other viruses! This means that Monarch butterflies are effectively naturally Genetically Modified Organisms (GMOs).


(13.8 MB, 15 m... Read More

BacterioFiles 259 - Fluke Froth Fosters Fester Fixing

This episode: I converse with Dr. Michael Smout about a liver fluke parasite could help heal chronic wounds more quickly!


(13.4 MB, 14.6 minutes)


Show notes: 
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MWV 105 - Understanding the Pathogenesis of the Emerging Zika Virus

Dr. Michael Diamond, 2016 Elizabeth O. King Lecturer, has worked for the past two decades investigating how viruses work, with a goal of defining basic principles of pathogenesis and host immune restriction. His talk in this podcast focuses on how his laboratory has studied three emerging mos... Read More

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