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A chromosome in every cell: PprA funcitons in chromosome segregation after Deinococcus radiodurans irradiation

Exposure to reactive oxygen species, exposure to ionizing radiation, exposure to UV light – all of these are dangerous because of their potential to alter DNA sequences. Changes in DNA can affect a protein coding sequence, potentially influencing its function, but changes in regulatory regions c... Read More

The switch from trivalent to bivalent oral poliovirus vaccine: Will it lead to polio?

In four months, 155 countries will together switch from using trivalent to bivalent oral poliovirus vaccine. Will this change lead to more cases of poliomyelitis? Read More

TWiV 374: Discordance in B

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiEVO 4: Taking the mystery out of the mystery of mysteries

Nitin Phadnis joins Nels and Vincent to explain how he identified a gene that is responsible for male inviability in hybrids from a cross between two species of fruit flies. Read More

Zika virus and microcephaly

Three reports have been published that together make a compelling case that Zika virus is causing microcephaly in Brazil. Read More

Changing the mindset of a pathogen-based vaccine

It’s hard to turn on the news at the moment and not hear about the latest emerging disease, Zika. The filovirus joins a cadre of infectious diseases spread by arthropod vectors – meaning the disease is passed between infected individuals via insect bites. A long list of microbes are spread this ... Read More

TWiM #121: A plague of pathogens

Filmed live at ASM Biodefense 2016 with special guests: Rebekah Kading and Wyndham Lathem.


Fr... Read More

Foot and mouth disease virus: a global threat to agriculture

An important and sometimes overlooked issue of infrastructure is food security. American agriculture and related industries represent $1.5 trillion U.S. dollars and 17% of U.S. jobs. These workers provide the meat, eggs, dairy, and produce that many take for granted will end up on grocery shelve... Read More

Catching Ebola virus in the act of fusion

Since the first outbreak of Ebola virus in 1976, the frequency and scale of the deadly disease’s outbreaks have increased. The 2014-2015 outbreak in West Africa caused 11,000 deaths, precipitated panic at airports and emergency rooms worldwide, and renewed the urgency to find cures.


Kartik ... Read More

Scientists, share your Zika virus reagents!

Today I learned that a number of investigators refuse to share their samples of Zika virus with other laboratories.

There are countless stories about scientists not sharing reagents because they want to be the first to make a discovery. This behavior allows them to publish first, secure more ... Read More

What is lurking in your bread and beer?

There are countless examples of plant, animal and bacterial viruses that cause severe symptoms of disease, sometimes with considerable socio-economic consequences. Viruses of fungi, otherwise known as ‘mycoviruses’, infect many medically and commercially important fungi, including the brewers an... Read More

TWiP 103: Scroll down, please

The TWiP-scholars solve the case of the Housewife from Kolkata, discuss mutations in the IL17 gene associated with cerebral malaria, and hear a case presentation from guest Michael Libman.


Hosts:  Read More

8th grader petri dishes - seeking help to identify colonies

I did a study of hand washing and hand sanitizer. Is anyone on the list willing to help me identify what grew from my unwashed and even washed hands? I attach three photos representing the yellow, white and orange growths found after several days on agar plates. Thank you so much in advance. Read More
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