If the reader does not believe that viroids and satellites are distinctive, then surely prions, infectious agents composed only of protein, must impress.
The question of whether infectious agents exist without genomes arose with the discovery and characterization of infectious agents associat... Read More
Paul Duprex joins the TWiV team to discuss the current moratorium on viral research to alter transmission, range and resistance, infectivity and immunity, and pathogenesis.
Vincent, Dickson, and Daniel provide the solution to last week's case study, present a new one, and discuss how immune suppression by nematodes increases tuberculosis fatality in African buffalo.
Dear Vincent & Dickson… and Daniel,
I always enjoy listening to TWIP here in Kona, Hawaii.
Our weather today is 79ºF and clear but we have just experienced a record 25-year overnight low of 54ºF,
Satellites are subviral agents that differ from viroids because they depend on the presence of a helper virus for their propagation. Satellite viruses are particles that contain nucleic acid genomes encoding a structural protein that encapsidates the satellite genome. Satellite RNAs do not encod... Read More
Hosts: Vincent Racaniello
Special guest: Rob Knight
Vincent meets up with Rob Knight to talk about the technology that has... Read More
Genomes of non-defective viruses range in size from 2,400,000 bp of dsDNA (Pandoravirus salinus) to 1,759 bp of ssDNA (porcine circovirus). Are even smaller viral genomes possible? The subviral agents called viroids provide an answer to this question.
Viroids, the smallest known pathogens, ar... Read More
This episode: A protein from gut bacteria has been tentatively linked with a human protein related to eating disorders!
(11.4 MB, 12.4 minutes)
Vincent speaks with John Coffin about his career studying retroviruses, including working with Howard Temin, endogenous retroviruses, XMRV, chronic fatigue syndrome and prostate cancer, HIV/AIDS, and his interest in growing cranberries.
Host: Read More
The TWiVers review the outcomes of two recent phase 3 clinical trials of a quadrivalent dengue virus vaccine in Asia and Latin America.
Vincent and Dickson welcome new TWiP host Daniel Griffin to discuss the association of a new Mycoplasma with trichomoniasis, and to introduce a new feature to the show, a case study.
Hello Dr Racaniello and Despommier,
I recently saw an article about the paper linked below on Science Daily and thought it might be worth a discussion on TWIP. It is about the possibility of bed bugs being a vector for T. cruzi. I would love to... Read More
The polio eradication and endgame strategic plan announced by the World Health Organization in 2014 includes at least one dose of inactivated poliovirus vaccine (IPV). Since 1988, when WHO announced the polio eradication plan, it had relied exclusively on the use of oral poliovirus vaccine (OPV)... Read More
This episode: Modified probiotic bacteria could reduce life-threatening allergies!
(6.3 MB, 6.8 minutes)
The TWiV gang reviews ten fascinating, compelling, and riveting virology stories from 2014.
The late computer scientist Randy Pausch wrote many inspirational things about life and academia during his struggle with pancreatic cancer. As we approach 2015, his words are helpful to me, and perhaps to others. About life, about academia, about helping others...and making our dreams come tr... Read More
This episode: When sensing an infection, mice make sure to keep their gut bacteria well-fed. And it pays off!
(11.8 MB, 13 minutes)
On his second trip to Brazil, Vincent joins Eurico to speak with four young virologists, Gustavo, Cintia, Tatiana, and Suellen, about their work and their prospects for careers in science.
Host: Read More
The general program for the 2015 American Society of Microbiology meeting in New Orleans is out, and registration is now open. The sessions look incredible, and I've listed them below as I imagine they might resonate with many of the readers of this blog. The bolded sessions look particularly in... Read More