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Additives to boost vaccine responses not sufficient to protect obese mice from influenza

At St. Jude Children’s Research Hospital in Memphis, Tenn., scientist Stacey Schultz-Cherry has been studying the impact of obesity on influenza severity.

“We saw during the 2009 flu pandemic that there’s an epidemiological link between people getting severe flu and being obese,” says Schultz... Read More

MetaPalette: a k-mer Painting Approach for Metagenomic Taxonomic Profiling and Quantification of Novel Strain Variation

Taxonomic profiling is a challenging first step when analyzing a metagenomic sample. This work presents a method that facilitates fine-scale characterization of the presence, abundance, and evolutionary relatedness of organisms present in a given sample but absent from the training database. We ... Read More

Molecular Analysis and Expression of bap Gene in Biofilm-Forming Multi-Drug-Resistant Acinetobacter baumannii. Reports of Biochemistry & Molecular Biology 2016


Background: Acinetobacter baumannii is commonly resistant to nearly all antibiotics due to presence of antibiotic resistance genes and biofilm formation. In this study we determined the presence of certain antibiotic-resistance genes associated with biofilm production and the influen... Read More

BacterioFiles 261 - Pilfered Parasitoid Proteins Protect Prey

This episode: Viruses domesticated by parasitoid wasps have transferred wasp genes to caterpillar victims, allowing them to survive deadly infections from other viruses! This means that Monarch butterflies are effectively naturally Genetically Modified Organisms (GMOs).

(13.8 MB, 15 m... Read More

TWiV 400: Harold '400' Varmus, a scientist for all seasons

The TWiV team is together in New York City for a conversation with Nobel Laureate Harold Varmus about his remarkable career in science.

Hosts: Vincent Racaniello Read More

The classic and current studies of bacterial endospore morphology

Recently, one of the Journal of Bacteriology Classic Spotlight series highlighted the numerous studies on bacterial spores that have been published in the journal throughout the years. Bacterial endospores, the resilient and relatively quiescent bacterial structures first identified in the 1800s... Read More

Is it safe to go into the ocean? Standardizing molecular methods for water safety surveillance

Have you ever gone to the beach, ready for a day of sun and sand, only to find a warning sign? One of the most common reasons beaches close is due to the presence of coliform bacteria. These indicator bacteria, such as Escherichia coli, are used as markers for fecal waste, since their presence c... Read More

ASMCUE Happenings 2016

No matter the niche field a scientist pursues, there is one aspect of almost all career paths that scientists have in common: teaching. Whether lecturing a quorum of undergraduates about bacterial genetics, mentoring a research fellow as they learn the lab protocols, or presenting an invited lec... Read More

Long Read: How Miraculous Microbes Help Us Evolve Better, Faster, Stronger

Smithsonian.com delves into the weeds of horizontal gene transfers (HGT) in bacteria. A feat that is largely unique to bacteria, it allows bacteria to trade DNA with other bacteria.

Bacteria can "exchange DNA as easily as we might exchange phone numbers, money or ideas".

Explore some of ... Read More

Two birds with one stone: E. faecium cotransfers drug resistance determinants by homologous recombination

The Gram-positive bacterium Enterococcus faecium is a member of the ESKAPE pathogens for which drug resistance has been a growing problem. How E. faecium becomes drug resistant has been a long-standing question, and is the focus of a new study now available in Antimicrobial Agents and Chemothera... Read More

The Epidemiology and Transmissibility of Zika Virus in Giradot and San Andres Island, Colombia, Sept. 2015 to Jan. 2016

Transmission of Zika virus (ZIKV) was first detected in Colombia in September 2015. As of April 2016, Colombia had reported over 65,000 cases of Zika virus disease (ZVD). We analysed daily surveillance data of ZVD cases reported to the health authorities of San Andres and Girardot, Colombia, bet... Read More

Memory loss caused by a virus

Well you may ask what virus ?

and I tell you West Nile Virus ( but I want to change it to WNV ). Every year when mosquito season arrives it will bring a lot of diseases . one of them is the memory loss. you may ask how does memory loss concern WNV?

Thousands of people are liv... Read More

BacterioFiles 260 - Endoriftia Evacuate Expired Employers

This episode: Bacteria in hydrothermal vents that feed their host tubeworms evacuate when their hosts perish!

(9 MB, 9.8 minutes)

Show notes: 
Journal Paper:

Klose J, Polz MF, Wagner M, Schimak MP, Gollner S, Bright M. 2... Read More

TWiV 399: Zika la femme

The latest Zika virus news from the ConTWiVstadors, including a case of female to male transmission, risk of infection at the 2016 summer Olympics, a DNA vaccine, antibody-dependent enhancement by dengue antibodies, and sites of replication in the placenta.

Hosts:  Read More

TWiP 113: Flying pigs

The TWiP ternion solve the case of the Man from Mexico, and discuss a transgenic toxoplasma vaccine for chickens using Eimeria tenella.

Hosts: Vincent Racaniello Read More

TWiV 398: Permission to be intuitive

Vincent speaks with Sandy Weller about her career and her work on the mechanisms of synthesis, maturation, cleavage and packaging of viral DNA genomes.

Host: Vincent Racaniello 

Guest: ... Read More

TWiM 131: Mice behaving badly

Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.

Hosts: Vinc... Read More

Disarming a pathogen's ability to cause disease

The anaerobic, Gram-positive Clostridium difficile is a big problem. It causes rampant diarrhea and tissue necrosis, with more than 150,000 annual cases in the United States alone. Many of the disease manifestations of C. difficile are mediated by two exotoxins that C. difficile produces: TcdA a... Read More

Multi Omics Measurements of Single Samples #mSystems

In systems biology studies, the integration of multiple omics measurements (i.e., genomics, transcriptomics, proteomics, metabolomics, and lipidomics) has been shown to provide a more complete and informative view of biological pathways. Thus, the prospect of extracting different types of molecu... Read More

One microbial pathogen 'disguised' as another leads to misdiagnoses

If it looks like a duck and quacks like a duck, it’s likely a duck – so goes the saying that illustrates the simplest explanation is usually the right one. But what about duck decoys used in conjunction with bird calls? Misidentification can be a deadly error – and the same goes for microbes. Mi... Read More
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