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Toward better understanding of fecal microbiota transplants

In recent years, researchers have learned that gut microbiota play a role in a number of human diseases, including Clostridium difficile infection, irritable bowel syndrome, Parkinson’s disease, and autism spectrum disorder. The revelations have scientists hopeful that fecal microbiota transplan... Read More

A suggested bundle to reduce carbapenem use

Too many carbapenems used in your hospital? Worried about carbapenem resistance? There is no magic bullet... Here is a suggested bundle to consider utilising to reduce carbapenem use. As with all bundles, it may be difficult to show a measurable effect with each individual component, but when al... Read More

TWiV 420: Orthogonal vectors

The TWiV gurus describe how to use an orthogonal translation system to produce infectious but replication-incompetent influenza vaccines.


Hosts: Vincent Racaniello Read More

SUBMIT MICROBE ABSTRACTS NOW: ONE IN FIVE ACCEPTED WILL BE ORAL PRESENTATION

The call for abstracts is now open for Microbe 2017, the premier microbiology conference hosted by the American Society for Microbiology. This is your opportunity to submit your important research in the microbial sciences to the largest scientific audience, with a 50% higher chance of presentin... Read More

TWiM #141: Nutritional immunity and polymicrobial infections

Jennifer joins Vincent, Elio, and Michael to talk about the work of her laboratory on how a respiratory virus enhances bacterial growth by dysregulating nutritional immunity.


Hosts: Vincent Racaniello, ... Read More

TWiM 141 Letters

Tom writes:


For the article letter about microbial batteries, I think CV refers to Capacitance times Voltage, which is stored charge. In electronics, current is abbreviated I not C.


The claim in the letter got me thinking about microbial batteries and I wrote ... Read More

Zika virus placental infection differs in maternal- and fetal-derived tissues

The World Health Organization downgraded the spread of Zika virus from a Public Health Emergency of International Concern on November 22nd, but Zika virus infection remains an important emerging infection with an incompletely understood infection cycle. The better scientists understand how the v... Read More

In case you missed it: best of mBiosphere 2016

From archaeal viruses to zoonotic diseases, the breadth of microbiology stories covered on mBiosphere in 2016 was impressive. Here are some of the best posts on mBiosphere from throughout this past year:
Read More

¿Is it possible to teach microbiology with Twitter?

Here, we present the results of our pioneering experience teaching a full Basic Microbiology course via Twitter (#microMOOCSEM), consisting of 28 lessons of 40-45 minutes duration each, at a tweet per minute rate during 10 weeks. Read More

The Power of the Microbiology Report Comment.

Looking to change people's behavior with regards to microbiology sampling? Look no further than the result report... Read More

BacterioFiles 280 - Saccharomyces Smash Small Spaces

This episode: Microbes in tight spaces grow so much they can build up pressure and burst out!


(5.5 MB, 6 minutes)


Show notes: 


News... Read More

TWiV 419: The selfless gene

The TWiVrific gang reveal how integration of a virophage into the nuclear genome of a marine protozoan enhances host survival after infection with a giant virus.


Hosts: Vincent Racaniello Read More

"The end of anti-microbial susceptibility breakpoints as we know them?"

Susceptibility break points are a dirty compromise between clinical, pharmacokinetic. and epidemiological break points. Because they are a necessary compromise, there will always be disagreement, and they can never be perfect. Is there a better way? Read More

Carbapenem-resistant bacteria isolated from a pig farm in the United States

While carbapenems aren’t allowed to be given to feedlot animals, other beta-lactam antibiotics are. This is a large class of drugs that includes extended-spectrum cephalosporin drugs. There is no direct line between the use of these extended-spectrum cephalosporins and selection for carbapenem r... Read More

Microbiology, Creativity, and Extra Credit

In this blog post, I share the creative projects that my Biology 350 (Microbiology) micronauts created this semester. They range from video parodies, to prose poems, to short-short stories to sculptures and needlepoint. Enjoy! Read More

Unlocking cryptic Strepomyces genes in the search for potential new antibiotics

Actinobacteria are the bacterial phylum responsible for production of many clinically-relevant antibacterial compounds. Streptomyces is a soil-dwelling genus of actinobacteria that produces drugs like neomycin and chloramphenicol. Despite deriving many antibiotics already from Streptomyces, coul... Read More

TWiP 122: If the thunder don't get you, the lightning will

The TWiPniks docs solve the case of the Female from Peru with Epistaxis, and discuss the effect of community deworming on immunosuppression.


Hosts: Vincent Racaniello Read More

"The Good and Bad of Lab Automation"

I am talking here specifically about automation of the bacterial culture process, using Kiestra TLA (installed in my own lab early 2016), Copan WASP, etc. A useful bullet point summary for those who are considering a business case for their own laboratory. Read More

"Too much knowledge..."

Are we, as microbiologists, getting too clever? Is our increasing theoretical knowledge actually hindering us in our goal of effective and realistic antimicrobial stewardship? Read this article to find out more! Read More

Discovery-based research as curriculum basis: increasing student engagement through small world initiative

If you are currently a microbiologist, chances are your introductory microbiology lab course syllabus hadn’t changed for decades. The course likely culminated in each student receiving an unknown bacterial sample, the identity of which was uncovered by applying techniques learned during the seme... Read More
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