Jason Roberts, a virologist at the Victorian Infectious Disease Reference Laboratory in Melbourne, Australia, creates three-dimensional simulations of viruses showing how the molecules that make up the capsid and genome might move in very short periods of time. I visited Jason in his laboratory ... Read More
This episode: Bacteria from wastewater treatment sludge can produce lots of biodegradable plastic!
(7.1 MB, 7.75 minutes)
The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs — and even DNA fragments associated with anthrax and Bubonic plague — according to a citywide microbiome map published today by Weill Corne... Read More
Vincent, Dickson, and Daniel solve last week's case study, present a new one, and reveal how secreted proteins from a helminth prevent diabetes in mice.
Dear Vincent, Dickson and Daniel,
I like your idea of a TWIP coffee mug prize (or maybe a mug discount).
In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More
Animal associated S. aureus are distinct from human strains but some recent studies suggested the human infection caused by animal origin strain of MRSA. Extensive and unregulated use of antibiotic in animal husbandry might be one of the causes for development of multidrug resistant strain. Tran... Read More
A paper just published in nature:
reports an effective antibiot... Read More
This episode: Carbon monoxide-eating bacteria get modified to produce more useful products!
(16 MB, 17.5 minutes)
... Read More
Dr. Vincent Racaniello is the Higgins Professor of Microbiology and Immunology at the college of Physicians and Surgions of Columbia University. Along with his academic research, he is known for expanding knowledge with great contributions through his virology blog virology.ws, and his wide podc... Read More
If the reader does not believe that viroids and satellites are distinctive, then surely prions, infectious agents composed only of protein, must impress.
The question of whether infectious agents exist without genomes arose with the discovery and characterization of infectious agents associat... Read More
Paul Duprex joins the TWiV team to discuss the current moratorium on viral research to alter transmission, range and resistance, infectivity and immunity, and pathogenesis.
Vincent, Dickson, and Daniel provide the solution to last week's case study, present a new one, and discuss how immune suppression by nematodes increases tuberculosis fatality in African buffalo.
Dear Vincent & Dickson… and Daniel,
I always enjoy listening to TWIP here in Kona, Hawaii.
Our weather today is 79ºF and clear but we have just experienced a record 25-year overnight low of 54ºF,
Satellites are subviral agents that differ from viroids because they depend on the presence of a helper virus for their propagation. Satellite viruses are particles that contain nucleic acid genomes encoding a structural protein that encapsidates the satellite genome. Satellite RNAs do not encod... Read More
Hosts: Vincent Racaniello
Special guest: Rob Knight
Vincent meets up with Rob Knight to talk about the technology that has... Read More
Genomes of non-defective viruses range in size from 2,400,000 bp of dsDNA (Pandoravirus salinus) to 1,759 bp of ssDNA (porcine circovirus). Are even smaller viral genomes possible? The subviral agents called viroids provide an answer to this question.
Viroids, the smallest known pathogens, ar... Read More
This episode: A protein from gut bacteria has been tentatively linked with a human protein related to eating disorders!
(11.4 MB, 12.4 minutes)