The entry of enveloped viruses into cells begins when the membrane that surrounds these virus particles fuse with a cell membrane. The process of virus-cell fusion must be tightly regulated, to make sure it happens in the right cells. The fusion activity of measles viruses isolated from the brai... Read More
This episode: Programming bacteria to sense and keep genomic records of environmental inputs!
(15.9 MB, 17.4 minutes)
In this short blog post, I "write" on Petri dishes with bioluminescent bacteria to create words and poems in "living light." I also write a haiku to quorum sensing in the same style! Read More
Presentation by Anthony S. Fauci, MD, Director, NIAID/NIH, Bethesda, MD, at the ASM Biodefense 2015 Meeting in Washington, D.C. on Feb 11, 2015. Read More
Jason Roberts, a virologist at the Victorian Infectious Disease Reference Laboratory in Melbourne, Australia, creates three-dimensional simulations of viruses showing how the molecules that make up the capsid and genome might move in very short periods of time. I visited Jason in his laboratory ... Read More
This episode: Bacteria from wastewater treatment sludge can produce lots of biodegradable plastic!
(7.1 MB, 7.75 minutes)
The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs — and even DNA fragments associated with anthrax and Bubonic plague — according to a citywide microbiome map published today by Weill Corne... Read More
Vincent, Dickson, and Daniel solve last week's case study, present a new one, and reveal how secreted proteins from a helminth prevent diabetes in mice.
Dear Vincent, Dickson and Daniel,
I like your idea of a TWIP coffee mug prize (or maybe a mug discount).
In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More
Animal associated S. aureus are distinct from human strains but some recent studies suggested the human infection caused by animal origin strain of MRSA. Extensive and unregulated use of antibiotic in animal husbandry might be one of the causes for development of multidrug resistant strain. Tran... Read More
A paper just published in nature:
reports an effective antibiot... Read More
This episode: Carbon monoxide-eating bacteria get modified to produce more useful products!
(16 MB, 17.5 minutes)
... Read More
Dr. Vincent Racaniello is the Higgins Professor of Microbiology and Immunology at the college of Physicians and Surgions of Columbia University. Along with his academic research, he is known for expanding knowledge with great contributions through his virology blog virology.ws, and his wide podc... Read More
If the reader does not believe that viroids and satellites are distinctive, then surely prions, infectious agents composed only of protein, must impress.
The question of whether infectious agents exist without genomes arose with the discovery and characterization of infectious agents associat... Read More
Paul Duprex joins the TWiV team to discuss the current moratorium on viral research to alter transmission, range and resistance, infectivity and immunity, and pathogenesis.
Vincent, Dickson, and Daniel provide the solution to last week's case study, present a new one, and discuss how immune suppression by nematodes increases tuberculosis fatality in African buffalo.