In this video Stephen L. Mayo, Bren Professor of Biology and Chemistry, California Institute of Technology, discusses the challenges of designing new proteins that fold into a particular structure or perform a particular function. One method is to computationally design a protein based solely up... Read More
Evolutionary geneticist Francisco Ayala wasn't always attracted to life in the laboratory. As a young man in Spain, Ayala was ordained as a Dominican priest. Within a year, though, he gave up it up to study genetics at Columbia University. Since then, Ayala's research has focused on parasitic pr... Read More
Viruses can be transmitted to completely new host species that they have not previously infected. Usually host defenses stop the infection before any replication and adaptation can take place. On rare occasions, a novel population of viruses arises in the new host. These interspecies infections ... Read More
Elio Schaechter of Small Things Considered ponders a recent discovery that small multicellular animals, members of the Loricifera and metazoa groups, are able to survive in an anoxic environment known as L’Atalante Basin, a brine “lake” at the bottom of the Mediterranean.
"Life without air—a ... Read More
Abstracts submitted for this year's ASM Conference for Undergraduate Educators "Microbrew: Mixing Ideas for Successful Teaching Strategies in
Microbiology" sessions are now available.
Just 23 days left until San Diego, hope to see you there!
Chair, ASMCUE 2010 Steering ... Read More
We typically spend close to 90 percent of our time inside - at school, work and home. While outdoor air quality is very important, so too is the quality of the air we breathe at home and the office. Yet most of us know very little about the condition of our indoor climate. The chemicals ... Read More
I really enjoyed your podcast about reverse transcription. I was wondering what makes retroviruses like HIV impossible for our bodies fight off. Are there any retroviruses that can be eliminated from the body?
I was browsing on the "Chronic ... Read More
On episode #79 of the podcast This Week in Virology, Vincent and Alan converse about making published science accessible to everyone, global eradication of poliomyelitis, and whether a plant virus c... Read More
A recent paper published in PLoS One looks at the relationship between alcohol consumption and Anopheles gambiae (the primary African malaria vector).
Malaria and alcohol consumption both represent major public health problems. Alcohol consumption is rising in developing countrie... Read More
On March 18, 2010, Roberto Kolter, Harvard Medical School and ASM President, gave a presentation to a group of graduate and postdoctoral students on why scientists need to be able to communicate effectively. This talk opened up the 2010 ASM Scientific Writing and Publishing Institute that... Read More
In December of last year, Julian Davies, Professor emeritus at the University of British Columbia and a Fellow of the Royal Society, authored an amusing post that essential... Read More
Alkaline lysis was first described by Birnboim and Doly in 1979 (Nucleic Acids Res. 7, 1513-1523) and has, with a few modifications, been the preferred method for plasmid DNA extraction from bacteria ever since. The easiest way to describe how alkaline lysis works is to go through the procedure ... Read More
Dear Vincent and Dick Just a quick message to say thank you for this informative and fun podcast series, I have enjoyed all three episodes and hope to listen to many more. Jusy the right thing for a former leishmaniac, now teache
Dickson reads his story about sparganosis caused by the diphyllobothroid tapeworm Spirometra mansonoides.
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Phenol extraction is a commonly used method for removing proteins from a DNA sample, e.g. to remove proteins from cell lysate during genomic DNA preparation. It’s commonly used, but not commonly understood.
This article describes the basic protocol and explains solvents in detail before an ex... Read More
One of the very first things you need to do when getting set up for quantitative PCR (qPCR) is to determine the efficiency of the assay because knowing the assay efficiency is critical to accurate data interpretation. And you have to do this every time you design and purchase a new primer pair.
... Read More
In a previous article, we discussed the basic characteristics of biofilm samples and factors that influence sample prep and handling. Today we want to share with you some very important tips for isolation of DNA or RNA from biofilm samples. After working with numerous different biofilms and bio... Read More
All mammalian genomes contain genes encoding Apobec proteins. Several members of this protein family (the name stands for apolipoprotein B mRNA editing complex) are induced by interferon and are intrinsic antiretroviral proteins. Apobec proteins inhibit the replication of XMRV, a new human retro... Read More
Theoretical physicist and futurist Michio Kaku looks at the revolution in genetics and biotechnology, which promises unprecedented health and longevity but also raises fears of a future where we can genetically engineer people. The documwentary asks will we, as transhumanists expect, evolve into... Read More