The influenza virus neuraminidase (NA) protein is required for virus release from the cell, a property exploited by the antiviral drugs oseltamivir (Tamiflu) and zanamavir (Relenza). During clinical testing of oseltamivir in 2001, some individuals shed drug-resistant viruses with an amino acid c... Read More
From time to time, we dip into the microbiology blog by César Sánchez, Twisted Bacteria, and, with his permission, "borrow" a post such as this one about pneumonia and pneumococci, fratricide at the cellular level, and a pretty protein. And there's a video too!
"A few days ago I w... Read More
The video of the seminar given by Dr. Shipley on how to get your qPCR data published is available now at the Source link.
Dr. Shipley is the director of the Quantitative Genomics Core Laboratory where they have been performing and optimizing assays for qPCR for the last 13 years. He is one o... Read More
I found your podcast through the Microbe World website. Thanks to Microbe World, I've been unable to sate my thirst for knowledge about the microscopic organisms that act as the foundation for our planet. So, I stumble across a podcast about viruses? Hel... Read More
When infection with hepatitis C virus goes from acute to chronic, severe liver disease may occur which requires organ transplantation. Nearly 200 million people are chronically infected with HCV, necessitating approaches to preventing and treating infections. No HCV vaccine is available, and cur... Read More
Jeff Fox, Current Topics and Features Editor of Microbe Magazine, talks with Harald Huber of the Johann Wolfgang Goethe University in Frankfurt, Germany. Huber and his collaborators have looked at the archaeon Ignicoccus hospitalis and found a very unusual cellular envelope architecture, un... Read More
Synthetic biology hit the headlines when Craig Venter recently announced the creation of Synthia – the first organism with a computer as a parent.
JCVI-syn1.0, as the artificial microbe is officially known, will become a poster child for synthetic biology. But it was created from known geneti... Read More
Joanne Manaster is a woman on a mission. She loves science and she wants to introduce kids to everything there is to love about science.
So this summer, her mission is to stimulate the minds of children and teens everywhere by challenging them to read non-fiction science books. In collaborati... Read More
Microbial communities in the Gulf of Mexico have surely been impacted by the oil disaster over the last couple of weeks. Labs are now beginning to assess the damage done by collecting water onto filter membranes and shipping the filters back to their labs for DNA analysis.
A frequent question... Read More
On episode #85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses.
<... Read More
Seth Berkley explains how smart advances in vaccine design, production and distribution are bringing us closer than ever to eliminating a host of global threats -- from AIDS to malaria to flu pandemics. Read More
Robert H. Silverman, one of the authors on the study implicating the new human retrovirus XMRV as an etiologic agent of chronic fatigue syndrome, has written an excellent review article on the current status of research on the virus. The article is behind a paywall at Nature Reviews Urology, so ... Read More
This TED video captures Caig Venter's official announcement that his team created the first fully functioning, reproducing cell controlled by synthetic DNA. He explains how they did it and why the achievement marks the beginning of a new era for science. Read More
Have you ever read a research article with qPCR data and wished that the authors had given you more information about what they did or how they did it? Or have you ever felt your data was more heavily scrutinized and criticized compared to others? The MIQE guidelines serve to normalize the field... Read More
Hi Dick and Vincent,
I still love both of your podcasts and was very pleased when Dick referred to Claudius as I love the books about him. This malaria themed podcast made me realize that the historical part of parasitism is so interesting (I'm ... Read More
Vincent and Dickson continue their discussion of malaria, with emphasis on clinical aspects of the disease.
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Bacteria have been sexually promiscuous, swapping genes with gusto, for a very long time. More than 15% of E. coli's genome has arrived via horizontal gene transfer (HGT), with some 200 installments having turned up since it diverged from Salmonella 100 million years ago. And, as you are probabl... Read More