Here is my annual blogpost using #MicrobialSupremacy to wish all readers a very, very happy holiday season. I do this GFP and prodiosin, as well as luciferase! Enjoy a tiny bit of microbial art, relevant to the season? Read More
Vincent, Alan, Rich and Kathy discuss how interleukin 10 modulation of Th17 helper cells contributes to alphavirus pathogenesis.
This episode: Bacterial antivirus system could treat chronic herpes virus infections!
(10.9 MB, 11.9 minutes)
Vincent, Alan, Rich and Kathy discuss the association of a virus with sea star melting disease, and the finding of a phycodnavirus in the oropharynx of humans with altered cognitive functions.
Human influenza viruses replicate almost exclusively in the respiratory tract, yet infected individuals may also have gastrointestinal symptoms such as vomiting and diarrhea. In mice, intestinal injury occurs in the absence of viral replication, and is a consequence of viral depletion of the gut... Read More
Team of researchers guided by Dr.Sarita G Bhat had developed a novel plate based screening technique for DOPA/melanin producing bacteria.Screening was based upon the clear zone formation on a medium suplemented with L-tyrosine.This new approach can be utilized in faster and accurate screening of... Read More
Follow the reconstruction and simulation of poliovirus using the BlueGene/Q supercomputer at the Victorian Life Sciences Computation Initiative. The poliovirus model is being used as a basis for understanding antiviral drugs, virus infection and helps us to learn how to model related viruses suc... Read More
Recovering viral genomes from ancient specimens can provide information about viral evolution, but not many old nucleic acids have been identified. A study of 700 year old caribou feces reveals that viruses can be protected for long periods of time – under the right conditions. Read More
This episode: Remnants of viral infection left behind in squirrels' genome may protect them from incoming viruses!
(9.3 MB, 10.1 minutes)
Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells.
Host: Read More
This episode: Being raised with their mother and breastmilk vs. bottle-fed in a nursery significantly affects macaque microbiomes and their immune system profile!
(7.7 MB, 8.4 minutes)
Vincent, Alan, and Rich discuss how norovirus, an enteric virus, can replace the functions of the gut microbiome.
The current Ebola virus outbreak in West Africa has sickened over 14,000 people and has killed over 5,100. Health workers from around the world are attempting to halt this deadly disease. On November 19th, the American Society for Microbiology featured two of these health workers, Dr. Joseph ... Read More
This episode: Pathogenic and non-pathogenic microbes have different strategies for interacting with us, even when they have a common ancestor!
(14.9 MB, 16.3 minutes)
The TWiVbolans discuss the finding that human noroviruses, major causes of gastroenteritis, can for the first time be propagated in B cell cultures, with the help of enteric bacteria.
Hosts: Read More
Sea stars are lovely marine invertebrates with a round central body connected to multiple radiating legs (photo credit). In the past year millions of sea stars in the west coast waters of North America have melted into piles of slime and ossicles. Sea star associated densovirus might be the caus... Read More
Vincent and Dickson discuss the spread of P. knowlesi in Malaysia, and how Leishmania parasites protect the sandfly gut from bacterial infection.
I came across this paper and thought it sounded interesting for a discussion on TWiP:
Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection