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Virus-induced fever might change bacteria from commensal to pathogen

Neisseria meningitidis may cause septicemia (bacteria in the blood) and meningitis (infection of the membrane surrounding the brain), but the bacterium colonizes the nasopharynx in 10-20% of the human population without causing disease. Although understanding how the bacterium changes from a com... Read More

World Polio Day

As a virologist who has worked on poliovirus since 1979, I would be remiss if I did not note that today, 24 October, is World Polio Day. World Polio Day was established by Rotary International over a decade ago to commemorate the birth of Jonas Salk, who led the first team to develop a vaccine a... Read More

Hepatitis B viruses in bats

Hepatitis B virus (HBV, illustrated) is a substantial human pathogen. WHO estimates that there are now 240,000,000 individuals chronically infected with HBV worldwide, of which 25% will die from chronic liver disease or hepatocellular carcinoma. The hepatitis B virus vaccine is highly effective ... Read More

Under the Microscope and the new science blog network by PopSci

Popular Science has just launched a new science blogging network with 13 blogs. Among them are two that have a focus on microbiology, Under the Microscope by JA Tetro and Our Modern Plague by Brooke Borel. Each blog has an inaugural post that outlines the author's vision for future subject matte... Read More

A saga of HeLa cells

We have been using HeLa cells in my laboratory since 1982, when I arrived at Columbia University Medical Center fresh from postdoctoral work with David Baltimore at MIT. I brought with me a line of HeLa cells and used them for 30 years for our research on viruses. Here is a story of how we lost ... Read More

BacterioFiles Micro Edition 138 - Slime Sustains Sidekick Pseudomonas

This episode: Slime mold cells carry bacteria with them, some for food and some for chemical warfare!




Download Episode (6.4 MB, 7 m... Read More

Oral bacteria resulting from poor dental hygiene shows a potential association with Alzheimer’s disease

Researchers examined samples from the brains of patients with and without dementia and found lipopolysaccharide, a component of Porphyromonas gingivalis, an oral bacterium, in four out of 10 Alzheimer’s disease brain samples.

“This clearly shows that there is an association between oral bacte... Read More

Stability of MERS Under Different Environmental Conditions (research)

The stability of Middle East respiratory syndrome coronavirus (MERS-CoV) was determined at 20°C – 40% relative humidity (RH); 30°C – 30% RH and 30°C – 80% RH. MERS-CoV was more stable at low temperature/low humidity conditions and could still be recovered after 48 hours. During aerosolisation of... Read More

TWiV 253: I don't know anything about sorghum



Hosts: Vincent Racaniello, Dickson Despommier, Read More

TWiM #65: Leanness is transmissible



Hosts: Vincent Racaniello and Michelle Swanson.


Vincent and Michelle reveal ... Read More

TWiM 65 Letters

Alexandra writes:


Dear TWIM-ers,


When I began listening to TWIV almost a year ago, I had just switched majors from philosophy to biology. I am now writing to you good people at TWIM at the end of my first undergraduate summer research gig, where I have had qui... Read More

Incidence of asymptomatic human influenza A(H5N1) virus infection

When virologists Fouchier and Kawaoka were isolating avian influenza H5N1 viruses that could transmit among ferrets by aerosol, there was consternation from some quarters that such viruses might escape from the laboratory and cause a pandemic in humans. Part of the fear came from the fact that t... Read More

BacterioFiles Micro Edition 137 - Germ's Jammer Jumpstarts Genes

This episode: Pathogen's CRISPR-Cas system (for defense against viruses) can be modified to change gene expression in mammals!




Download Epis... Read More

TWiV 252: Who read the last email?



Hosts: Vincent Racaniello, Dickson Despommier, Read More

Fouchier vs the Dutch government on influenza H5N1 research

Readers of this blog will remember the furor sparked by Fouchier’s experiments in 2011 in which he developed an avian influenza H5N1 isolate that could transmit among ferrets by aerosol. When Fouchier was ready to publish the results, the Dutch government required that Fouchier apply for an expo... Read More

TWiP 60: Urine a game of cat and mouse



Hosts: Vincent Racaniello and Dickson Despommier


Vincent and Dickson discus... Read More

TWiP 60 letters

Maureen writes:


Our vaccine unit here at NIH did a study of malaria vaccine with some promising results. I know Dickson has been a champion of conquering malaria.


http://www.scie... Read More

BacterioFiles Micro Edition 136 - Swarmers Send Secret Signals

This episode: Swarming predatory bacteria may be communicating through tubes!




Download Episode (6.3 MB, 6.9 minutes)


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TWiV 251: Don't kiss the camel



Hosts: Vincent Racaniello, Dickson Despommier, Read More

Interview of Dr. Zakaria Ahmed (The Shining star of Bangladesh)

I am International Outreach Coordinator of We The Microbiologist, a group to outreach the excellence and passion for Microbiology. I communicated Dr. Zakira Ahmad, for a formal interaction to discuss his excellence. I am glad beyond expectation that I had been called to his home with a warm welc... Read More

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