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The dual role of GALNT3 during influenza infection

Feeling under the weather? Are you congested, maybe having a hard time breathing, especially at night? Don’t worry – this is your body’s natural response to an infection. Mucus production is generally regarded as antimicrobial – it traps particles like virions before they can infect nearby host ... Read More

Zika from sex, the byway but not the highway

Can Zika virus be sexually transmitted? Perhaps in very rare cases, but the main mode of transmission is certainly via mosquitoes. That’s why I’ve shamelessly stolen a quote on this topic from Dr. William Schaffner of Vanderbilt University: Mosquito transmission is the highway, whereas sexual tr... Read More

MMP #9: Customizing phage by swapping tail genes to target specific pathogens

Host: Jeff Fox with special guest, Timothy Lu.


Lu, an Associate Professor of Biological Engineering and Electrical Engineering and Computer Science at Massachusetts Institute of Technology in Cambridge, Massachuse... Read More

TWiM #120: Snakes in trouble

Hosts: Vincent Racaniello and Elio Schaechter.


Vincent and Elio marvel in the finding that a phage tail-like struc... Read More

A chromosome in every cell: PprA funcitons in chromosome segregation after Deinococcus radiodurans irradiation

Exposure to reactive oxygen species, exposure to ionizing radiation, exposure to UV light – all of these are dangerous because of their potential to alter DNA sequences. Changes in DNA can affect a protein coding sequence, potentially influencing its function, but changes in regulatory regions c... Read More

TWiV 374: Discordance in B

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

Zika virus

The rapid spread of Zika virus through the Americas, together with the association of infection with microcephaly and Guillain-Barré syndrome, have propelled this previously ignored virus into the limelight. What is this virus and where did it come from?
Read More

A growing concern: why whooping cough incidence may be increasing in a highly vaccinated population

News headlines highlighting an outbreak of a vaccine-preventable disease often leave readers shaking their heads. These diseases – measles, chickenpox, whooping cough – could have been prevented if only the infected children had been vaccinated. Right? Well, in the case of whooping cough, the si... Read More

Microbiology, Cartoons, and Take Home Lessons!

In this blog post, I describe how I had students create their own cartoon depicting microbiological ideas and concepts that most tickled their fancy. I did this on their final exam, and the students came up with really interesting and entertaining ideas. IT's always interesting to see what stu... Read More

Ancient clay remedy proves its antibacterial powers in the lab

Near Kisameet Bay on the central coast of British Columbia sits a deposit of clay that covers 5 acres and spans a depth up to 42 feet in places. This vast smear formed 10,000 years ago as glacial melt filled a granite basin and fine minerals silted out.

The ancient clay likely holds secrets t... Read More

Scientists prove key aspect of evolutionary theory

Evolutionary theory predicts that pairs of chromosomes within asexual organisms will evolve independently of each other and become increasingly different over time in a phenomenon called the 'Meselson effect.' Researchers from the University of Glasgow have demonstrated the Meselson effect for t... Read More

Register for "The Exciting and Emerging Science of Microbial Research" FREE webinar on Feb 11

You are invited to attend "The Exciting and Emerging Science of Microbial Research" FREE webinar on February 11, 2016 from 6-7 pm MT - sign up now, space is limited!
Noah Fierer, CU Assoc. Professor & CIRES Fellow, and his graduate student, Hannah Holland-Moritz, will present their research in... Read More

TWiV 373: The distinguished virology career of Julius S. Youngner

 


Host: Vincent Racaniello 


Guest: Julius S. Youngner


Vincent... Read More

TWiEVO 4: Taking the mystery out of the mystery of mysteries

Nitin Phadnis joins Nels and Vincent to explain how he identified a gene that is responsible for male inviability in hybrids from a cross between two species of fruit flies. Read More

Will you share? Social versus selfish mechanisms affect selective conditions

The previous post mentioned the onset of antibiotic resistance as one of the scarier, if less sensationalist, outbreaks of our time. We generally discuss antibiotic resistance in medically relevant microbes (on this blog and in the news), where resistance means the ability of disease-causing mic... Read More

Whole-genome sequencing can help ID hospital outbreaks

Drug-resistant infections are becoming one of the scariest epidemics since the advent of antibiotic discovery. Although microbes like methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Klebsiella pneumoniae, and multidrug-resistant Pseudomonas aeruginosa are responsible for... Read More

TWiV 372: Latent viral tendencies

Hosts: Vincent RacanielloAlan DoveRich Condit Read More

TWiM #119: Power of one

Hosts: Vincent RacanielloMichael Schmidt, and Read More

TWiM 119 Letters

Jeanne writes:


Dear TWiM,
 
With regard to the question about culturing gut microbes from Drosophila:
 
I was lucky enough to take a sabbatical in the lab of Dr. Angela Douglas (http://angeladouglasl... Read More

Toward development of microarrays to test water safety

Imagine taking an ocean-side vacation, with the sun, sand, and water lulling you to relaxed bliss. After day at the beach, you experience an intense bout of stomach cramps and – more delicately put – GI distress. A rare day off is ruined because of a bug you picked up. Next, imagine a situation ... Read More

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