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BacterioFiles 279 - Hijacker Heightened Hyphal Heterogeneity

This episode: Fungi control their cell's growth and division with a protein from a virus, unlike all other kinds of eukaryote!


(8.9 MB, 9.75 minutes)


Show notes: 


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TWiV 418: Of mice and MERS

The TWiVsters describe a new animal model for MERS coronavirus-induced acute respiratory distress syndrome, produced by CRISPR/Cas9 editing of the mouse gene encoding an ortholog of the virus receptor.


Hosts:  Read More

Discovery-based research as curriculum basis: increasing student engagement through small world initiative

If you are currently a microbiologist, chances are your introductory microbiology lab course syllabus hadn’t changed for decades. The course likely culminated in each student receiving an unknown bacterial sample, the identity of which was uncovered by applying techniques learned during the seme... Read More

Carbapenem-resistant bacteria isolated from a pig farm in the United States

While carbapenems aren’t allowed to be given to feedlot animals, other beta-lactam antibiotics are. This is a large class of drugs that includes extended-spectrum cephalosporin drugs. There is no direct line between the use of these extended-spectrum cephalosporins and selection for carbapenem r... Read More

Unlocking cryptic Strepomyces genes in the search for potential new antibiotics

Actinobacteria are the bacterial phylum responsible for production of many clinically-relevant antibacterial compounds. Streptomyces is a soil-dwelling genus of actinobacteria that produces drugs like neomycin and chloramphenicol. Despite deriving many antibiotics already from Streptomyces, coul... Read More

TWiP 122: If the thunder don't get you, the lightning will

The TWiPniks docs solve the case of the Female from Peru with Epistaxis, and discuss the effect of community deworming on immunosuppression.


Hosts: Vincent Racaniello Read More

"The end of anti-microbial susceptibility breakpoints as we know them?"

Susceptibility break points are a dirty compromise between clinical, pharmacokinetic. and epidemiological break points. Because they are a necessary compromise, there will always be disagreement, and they can never be perfect. Is there a better way? Read More

Microbiology, Creativity, and Extra Credit

In this blog post, I share the creative projects that my Biology 350 (Microbiology) micronauts created this semester. They range from video parodies, to prose poems, to short-short stories to sculptures and needlepoint. Enjoy! Read More

"The Good and Bad of Lab Automation"

I am talking here specifically about automation of the bacterial culture process, using Kiestra TLA (installed in my own lab early 2016), Copan WASP, etc. A useful bullet point summary for those who are considering a business case for their own laboratory. Read More

"Too much knowledge..."

Are we, as microbiologists, getting too clever? Is our increasing theoretical knowledge actually hindering us in our goal of effective and realistic antimicrobial stewardship? Read this article to find out more! Read More
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