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This Week in Virology (TWiV) is a podcast – or netcast, as some prefer to call them, since you don’t need an iPod to listen – about viruses. It was begun in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center. Their goal was to have an informal yet informative conversation about viruses which would be accessible to everyone, no matter what their science background. We wanted to eventually bring other virologists into the conversation, to make it more varied and interesting. Alan Dove, a science writer, joined us late in 2008, and Rich Condit, a poxvirologist, joined in 2009. We’ve had a number of guests on the show and we’re always trying to get more.
Why are we doing this? Dick, Rich, and I have spent our entire academic careers directing research laboratories, so we have a lot of knowledge to share. Plus, we both enjoy teaching. Put those two things together, and you have TWiV. If you want to learn about viruses in a relaxing way, then TWiV is for you.
Vincent, Alan, and Kathy review the finding that rabies virus infection alters but does not kill neurons, and provide an update on the novel coronavirus in the Middle East.
Download TWiV 215 (66 MB .mp3, 92 min)
Tarwin - Plague Inc.
Vincent, Alan, and Kathy discuss how coagulation factor X binding to adenovirus activates the innate immune system, and a novel polyomavirus associated with brain tumors in raccoons.
Download TWiV 214 (56 MB .mp3, 78 min)
In their final episode of the year, the TWiV team reviews twelve cool virology stories from 2012.
Download TWiV 213 (88 MB .mp3, 122 min)
Matt - The flu vaccine controversy
Vincent and Stuart discuss why ignorance - all of what we don't know, and even what we don't know we don't know - is the driving force of science.
Download: 58 MB .mp3, 81 min
The TWiVerers answer listener email about genetically modified chickens, a hendra vaccine for horses, online education, curing color blindness, Roosevelt and polio, Th cells, and much more.
Download TWiV 212 (78 MB .mp3, 108 min)
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The TWiV four discuss an mRNA-based influenza vaccine, and a phage tubulin that forms a filamentous array in the host cell that is needed for positioning viral DNA.
Download TWiV 211 (70 MB .mp3, 97 min)
Stephen - WEHI.TV
The complete TWiV team reviews identification of the cell receptor for hepatitis B and D viruses, and the cell enzyme that cleaves the genome-linked protein from picornaviral RNA.
Download TWiV 210 (67 MB .mp3, 93 min)
Vincent, Dickson, Alan, and Kathy answer listener email about deformed wing virus, West Nile virus, FluMist, influenza in Canada, viruses and the tree of life, and more.
Download TWiV 209 (81 MB .mp3, 113 min)
Vincent is joined by special guest Jon Yewdell to discuss solutions for ending the current crisis in American biomedical research.
Download TWiV 208 (63 MB .mp3, 87 min)
Vincent, Alan, Matt, and Kathy review the use of silk to stabilize antibiotics and a viral vaccine, and an impaired-fidelity vaccine against SARS coronavirus.
Right-click to download TWiV 207 (76 MB .mp3, 106 minutes).