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This Week in Virology (TWiV) is a podcast – or netcast, as some prefer to call them, since you don’t need an iPod to listen – about viruses. It was begun in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center. Their goal was to have an informal yet informative conversation about viruses which would be accessible to everyone, no matter what their science background. We wanted to eventually bring other virologists into the conversation, to make it more varied and interesting. Alan Dove, a science writer, joined us late in 2008, and Rich Condit, a poxvirologist, joined in 2009. We’ve had a number of guests on the show and we’re always trying to get more.
Why are we doing this? Dick, Rich, and I have spent our entire academic careers directing research laboratories, so we have a lot of knowledge to share. Plus, we both enjoy teaching. Put those two things together, and you have TWiV. If you want to learn about viruses in a relaxing way, then TWiV is for you.
The TWiV team discusses recent cases of polio-like paralysis in California, and the virome of 14th century paleofeces.
Download TWiV 274 (87 MB .mp3, 120 min)
Alan - The science of science communication
Rich - Command and Control by Eric Schlosser
Dickson - Top 10 plant viruses
Vincent - Is the Nobel Prize good for science?
Kathy - Time to rethink graduate and postdoc education (YouTube)
Host: Vincent Racaniello
Vincent meets up with Ian and Thomas to discuss their finding that MERS-coronavirus has been circulating in dromedary camels in the Kingdom of Saudi Arabia since at least 1992.
Download TWiV Special MERS (28 MB .mp3, 38 min)
The TWiVome dissect the finding that interferon lambda alleles predict the outcome of hepatitis C virus infection.
Download TWiV 273 (75 MB .mp3, 103 min)
The TWiV team describes aphid control by using a viral capsid protein to deliver a spider toxin to plants, and a human endogenous retrovirus that enhances expression of a neuronal gene.
Download TWiV 272 (78 MB .mp3, 108 min)
The TWiV crew discusses two reports on viruses that might have crossed kingdoms, from plants to honeybees and from plants to vertebrates.
Download TWiV 271 (69 MB .mp3, 96 min)
Vincent and Rich discuss avian influenza virus and an antiviral drug against smallpox with Dennis and Yoshi at the ASM Biodefense and Emerging Diseases Research Meeting in Washington, DC.
Download TWiV 270 (61 MB .mp3, 84 min)
The complete TWiV team reviews evidence for sensing of herpesviral DNA in the nucleus by the cell protein IFI16.
Download TWiV 269 (74 MB .mp3, 102 min)
Vincent, Alan, Kathy, and Ashlee discuss fomites in physicians offices, plant virus factories involved in aphid transmission, and clues from the bat genome about flight and immunity.
Download TWiV 268 (77 MB .mp3, 106 min)
Vincent, Alan, Rich and Kathy review a protease essential for influenza pathogenesis in mice, and directionality of rhinovirus RNA exit from the capsid.
Download TWiV 267 (69 MB .mp3, 95 min)
Vincent, Alan, and Kathy discuss finding viruses in outer space, varying results obtained from personal genetic testing, and depletion of CD4 cells during HIV infection by pyroptosis.
Download TWiV 266 (70 MB .mp3, 97 min)
Emily - Dengue pillow