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This Week in Virology (TWiV) is a podcast – or netcast, as some prefer to call them, since you don’t need an iPod to listen – about viruses. It was begun in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center. Their goal was to have an informal yet informative conversation about viruses which would be accessible to everyone, no matter what their science background. We wanted to eventually bring other virologists into the conversation, to make it more varied and interesting. Alan Dove, a science writer, joined us late in 2008, and Rich Condit, a poxvirologist, joined in 2009. We’ve had a number of guests on the show and we’re always trying to get more.
Why are we doing this? Dick, Rich, and I have spent our entire academic careers directing research laboratories, so we have a lot of knowledge to share. Plus, we both enjoy teaching. Put those two things together, and you have TWiV. If you want to learn about viruses in a relaxing way, then TWiV is for you.
Guest: Esper Kallas
Esper and the Merry TWiXters analyze the latest data on Zika virus and microcephaly in Brazil, and discuss publications on a mouse model for disease, infection of a fetus, mosquito vector competence, and the cryo-EM structure of the virus particle.
Download TWiV 383 (90 MB .mp3, 125 min)
Esper - The Chaos by Gérard Nolst Trenité (pronunciation guide) and HIV pathogenesis course
Alan - Science Kombat
Dickson - Four steps to wiping out a mosquito
Vincent - Public lacks information on Zika virus
Kathy - Zika virus cryo-EM structure video
Nels and Ed join the TWiV team to talk about their observation that regulation of the human interferon response depends on regulatory sequences that were co-opted millions of years ago from endogenous retroviruses.
Download TWiV 382 (82 MB .mp3, 114 min)
Nels - Don't Get Me Started - Matt Giorgianni
Alan - Sun's magnetic field (paper)
Dickson - Most realistic dinosaur terrifies
Vincent - Top secret!
Kathy - Zika virus risk for US 50 cities (paper)
Ed - Watching comb jellies poop
Guest: Carl Zimmer
Carl Zimmer joins the TWiV team to talk about his career in science writing, the real meaning of copy-paste, science publishing, the value of Twitter, preprint servers, his thoughts on science outreach, and much more.
Download TWiV 381 (86 MB .mp3, 119 min)
Carl - Surprising benefit of viral DNA
Alan - Global ship traffic
Dickson - Music with 2000 marbles
Vincent - The whiteboard revolution
Kathy - How to interpret UK and American advisors
Rich - Carina Storrs, science writer
The TWiVeroos deliver the weekly Zika Report, then talk about a cryoEM structure of a plant virus that reveals how the RNA genome is packaged in the capsid, and MIMIVIRE, a CRISPR-like defense system in giant eukaryotic viruses.
Download TWiV 380 (80 MB .mp3, 110 min)
Guest: Scott Tibbetts
Scott Tibbetts joins the TWiVists to describe his work on the role of a herpesviral nocoding RNA in establishment of peripheral latency, and then we visit two last minute additions to the Zika virus literature.
Download TWiV 379 (85 MB .mp3, 115 min)
Greg Smith joins the TWiVirate to reveal how his lab discovered a switch that controls herpesvirus neuroinvasion, and then we visit the week's news about Zika virus.
Download TWiV 378 (87 MB .mp3, 119 min)
Alan - Science byline counting project
Dickson - Bill Nye on climate change
Vincent - Zdziarski's blog of things (Apple's motion to vacate)
Greg - Atlas, the next generation
Kathy - Sources of Chaco wood
Mark - How Dogs Love Us by Gregory Berns
Bohdan - The real reason for brains
The TWiVniks review the past week's findings on Zika virus and microcephaly, and reveal a chicken protein that provides insight on the restriction of transmission of avian influenza viruses to humans.
Download TWiV 377 (70 MB .mp3, 95 min)
Guest: Jeremy Luban
The TWiV team discusses the latest data on Zika virus, including ocular defects in infants with microcephaly, and isolation of the entire viral genome from fetal brain tissue.
Download TWiV 376 (80 MB .mp3, 109 min)
Alan - PhD Comics on gravitational waves
Dickson - 25 years of Hubble
Vincent - Amazon AWS TOS and Confirming Einstein
Rich - Mosquito mass production
Kathy - TileApp
Jeremy - IL17A and autism and The Perfect Theory by Pedro Ferreira
The TWiVziks present everything you want to know about Zika virus, including association of infection with microcephaly and Guillain-Barré syndrome, transmission, epidemiology, and much more.
Download TWiV 375 (92 MB .mp3, 125 min)
Alan - Jetstream Online School for Weather
Vincent - New virus watercolors from Michele Banks (one, two)
Rich - The Mad Virologist (Facebook, blog)
Kathy - Orcas in Antarctica
Jeremy - Pardis Sabeti on TED
Helen - Science Valentines
Carolyn - Three letter word missing from Zika warnings
Photos below from Esper Kallas, University of Sao Paulo, mentioned in this episode can be found at this link.
The TWiVniks consider the role of a cell enzyme that removes a protein linked to the 5'-end of the picornavirus genome, and the connection between malaria, Epstein-Barr virus, and endemic Burkitt's lymphoma.
Download TWiV 374 (84 MB .mp3, 104 min)
Alan - Indoor skydiving
Vincent - Cancer Virus by Crawford, Johannessen, and Rickinson
Rich - Wit
Kathy - The Only Woman in the Room by Eileen Pollack
Dickson - Show everyone your clinical data