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This Week in Virology

twiv

This Week in Virology (TWiV) is a podcast – or netcast, as some prefer to call them, since you don’t need an iPod to listen – about viruses. It was begun in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center. Their goal was to have an informal yet informative conversation about viruses which would be accessible to everyone, no matter what their science background. We wanted to eventually bring other virologists into the conversation, to make it more varied and interesting. Alan Dove, a science writer, joined us late in 2008, and Rich Condit, a poxvirologist, joined in 2009. We’ve had a number of guests on the show and we’re always trying to get more.

Why are we doing this? Dick, Rich, and I have spent our entire academic careers directing research laboratories, so we have a lot of knowledge to share. Plus, we both enjoy teaching. Put those two things together, and you have TWiV. If you want to learn about viruses in a relaxing way, then TWiV is for you.

TWiV 172: Two can be as bad as one

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Hosts: Vincent Racaniello and Kathy Spindler

Vincent and Kathy discuss how a virus may cause disease distant from its replication site, then review a day in the life of a senior microbiology professor.

Right-click to download TWiV 172 (74 MB .mp3, 102 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:tetramer

Weekly Science Picks

Kathy - Science prize for inquiry-based instruction (Alberts editorial, second winner)
Vincent - The long and winding road to a Ph.D.

Listener Pick of the Week

Greg - Correlation

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

 

TWiV 171: One is the loneliest number

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Hosts: Vincent RacanielloAlan DoveDickson Despommier, and Matt Frieman

Matt joins the TWiVarians to review virus production in single cells and single virion genomics.

Right-click to download TWiV 171 (67 MB .mp3, 92 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:single_virion_genomics

Weekly Science Picks

Matt - H5N1 research discussion
Dickson - The Golden Wand of Medicine by Walter J. Friedlander
Alan - Imagine Science Films
Vincent - E. coli: Good, Bad, and Deadly

Listener Pick of the Week

Daniel - The scale of the Universe
Stefan - A Legacy of Achievement

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

 

TWiV 170: From variolous effluvia to VLPs

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Hosts: Alan DoveRich Condit, and Dickson Despommier

Alan, Rich, and Dickson discuss Edward Jenner's paper on cowpox vaccine, then move 200 years later to modern vaccines against norovirus, influenza H5N1, and more.

Right-click to download TWiV 170 (72 MB .mp3, 100 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:cow_pock

Weekly Science Picks

Dickson - High-speed photography of falling drop
Rich - Biotechnology Research in an Age of Terrorism (NAP)
Alan - Lab Report videos (YouTube)

Listener Pick of the Week

Jim - The Blind Spot

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

 

TWiV 169: Epidemiology causes conclusions

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Hosts: Vincent Racaniello, Dickson DespommierRich ConditAlan Dove, and Michael Walsh

Michael and the TWiV team review epidemiology basics, including fatality ratios.

Right-click to download TWiV 169 (64 MB .mp3, 152 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:snow-cholera-map

Weekly Science Picks

Michael - Love my epi
Dickson - Bacteria array detects arsenic
Rich - Dunning-Kruger effect
Alan - Environmental Economics
Vincent - Don't censor influenza research

Listener Pick of the Week

Simon - The Great Mortality by John Kelly

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

 

TWiV 168: Super CalTech prophylaxis and ferret runny noses

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Hosts: Vincent Racaniello, Dickson DespommierRich ConditAlan Dove, and Welkin Johnson

Welkin joins the TWiV team for a discussion of HIV prophlaxis using vectored antibodies, and the influenza H5N1 virus studies in ferrets that were not redacted.

Right-click to download TWiV 168 (59 MB .mp3, 98 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

Weekly Science Picks

Welkin - Virtual PI (Nature)
Dickson - Drain the Ocean
Rich - Nova: To the Moon
Alan - Robert Falcon Scott on Twitter and the Terra Nova expedition
Vincent - Hello, Mr. Chips (I, Cringely)

Listener Pick of the Week Charlotte - And the Band Played On

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

 

TWiV 167: It starts with a cough

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Hosts: Vincent Racaniello, Dickson DespommierRich Condit, and Alan Dove

The complete TWiVome deconstructs the movie Contagion.

Right-click to download TWiV 167 (53 MB .mp3, 88  minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:lipkin_contagion

Weekly Science Picks

Dickson - Guinea Pig Doctors by Jon Franklin
Rich - Learn to appreciate technology and Everythings amazing and nobodys happy (YouTube)
Alan - JD Hooker slide collection
Vincent - iTunes U app and iBooks Author

Listener Pick of the Week Judi - Makers of Many Things by Eva March Tappan

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

 

TWiV 166: Breaking and entering

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Hosts: Vincent Racaniello, Dickson DespommierRich Condit, and Alan Dove

Vincent, Dickson, Rich, and Alan review cell proteins essential for entry of hepatitis C, Ebola, and measles viruses.

Please help us by taking our listener survey.

Right-click to download TWiV 166 (59 MB .mp3,  98 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:npc1_ebola

Weekly Science Picks

Dickson - What are you swimming with?
Rich -
Twelve monkeys
Alan - Kindle Touch
Vincent - Microbe news (thanks to Dave Winer)

Listener Pick of the Week
Eric - The Nature of Things with David Suzuki
Lance - Trials and Errors (Wired)

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

 

TWiV 165: The email zone

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Hosts: Vincent Racaniello, Dickson DespommierRich Condit, and Alan Dove

Vincent, Dickson, Rich, and Alan answer listener questions about XMRV, cytomegalovirus, latency, shingles vaccine, myxomavirus and rabbits, and more.

Please help us by taking our listener survey.

Right-click to download TWiV 165 (61 MB .mp3, 102 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:t4_tatoo-300x300

Weekly Science Picks

Dickson - Creation
Rich -
America's Science Decline
Alan - Out of context science
Vincent - The Scientist Top 10 Innovations 2011

Listener Pick of the Week
Jim - Christoph Adami: Finding life we can't imagine (TED)
Tim - Patient Zero (Radiolab)
Mary - Natural Obsessions by Natalie Angier
Jimmy -
Science Exchange

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

 

TWiV 164: Six steps forward, four steps back

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Hosts: Vincent RacanielloRich Condit, and Alan Dove

Vincent, Alan, and Rich review ten compelling virology stories of 2011.

Please help us by taking our listener survey.

Right-click to download TWiV 164 (60 MB .mp3, 99 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Ten virology stories of 2011:xmrv

  1. XMRV, CFS, and prostate cancer (TWiV 119, 123, 136, 150)
  2. Influenza H5N1, ferrets, and the NSABB (TWiV 159)
  3. The Panic Virus (TWiV 117)
  4. Polio eradication (TWiV 127, 149)
  5. Viral oncotherapy (TWiV 124, 131, 142, 156)
  6. Hepatitis C virus (TWiV 130, 137, 141)
  7. Zinc finger nuclease and HIV therapy (TWiV 144)
  8. Bacteria help viruses (TWiV 154)
  9. Human papillomaviruses (TWiV 126)
  10. Combating dengue with Wolbachia (TWiV 115, 147)

Links for this episode:

Weekly Science Picks

Rich - Fundamentals of Molecular Virology by Nicholas H. Acheson
Alan - Fetch, with Ruff Ruffman
Vincent - Year end reviews at Rule of 6ix and Contagions

Listener Pick of the Week
Garren - Trillion-frame-per-second video
Judi - iBioMagazine
Ricardo -
Brain Picking's 11 best science books of 2011

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

 

TWiV 163: What Rous wrought

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Hosts: Vincent Racaniello, Dickson DespommierRich Condit, and Alan Dove

Vincent, Dickson, Rich, and Alan review the 100 year old finding by Peyton Rous of a transmissible sarcoma of chickens, a discovery that ushered in the era of tumor virology.

Please help us by taking our listener survey.

Right-click to download TWiV 163 (61 MB .mp3, 102 minutes). Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:fungal-christmas-tree

Weekly Science Picks

Rich - The Log from the Sea of Cortez by John Steinbeck
Alan - Comet rise
Vincent - TWiV iPhone case

Listener Pick of the Week
Ronnie - How fungi celebrate Christmas
Kevin - EcoCyc app
Gabriel -
ImmGen app

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

 

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