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This Week in Virology

twiv

This Week in Virology (TWiV) is a podcast – or netcast, as some prefer to call them, since you don’t need an iPod to listen – about viruses. It was begun in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center. Their goal was to have an informal yet informative conversation about viruses which would be accessible to everyone, no matter what their science background. We wanted to eventually bring other virologists into the conversation, to make it more varied and interesting. Alan Dove, a science writer, joined us late in 2008, and Rich Condit, a poxvirologist, joined in 2009. We’ve had a number of guests on the show and we’re always trying to get more.

Why are we doing this? Dick, Rich, and I have spent our entire academic careers directing research laboratories, so we have a lot of knowledge to share. Plus, we both enjoy teaching. Put those two things together, and you have TWiV. If you want to learn about viruses in a relaxing way, then TWiV is for you.

TWiV 257: Caveat mTOR

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Hosts: Vincent RacanielloDickson DespommierAlan DoveRich Condit, and Kathy Spindler

The TWiV team consider how the kinase mTOR modulates the antibody response to provide broad protection against influenza virus, and explore the problems with scientific research.

Download TWiV 257 (74 MB .mp3, 102 min)

Subscribe (free): iTunesRSSemail

Links for this episodeMTOR-pathway

Weekly Science Picks

Dickson - Tesla Motors supercharger
Kathy
 - FASEB contest: Stand out for science
Alan - Natural History Museum virtual tour
Rich - Mauna Kea heavens
Vincent
 - FAA expands use of electronics on planes

Listener Pick of the Week

Peter - Score and ignore (pdf)

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TWiV 256: How mice say nodavirus

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Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

Vincent, Dickson, Alan, Rich, and Kathy review two papers that present evidence for RNA interference as an antiviral immunity mechanism in mammals.

Download TWiV 256 (70 MB .mp3, 96 min)

Subscribe (free): iTunesRSSemail

Links for this episode:98 siRNA

Weekly Science Picks

Dickson - Wildlife Photographers of the Year 2013
Kathy
 - John Holland's Emerging Infectious Disease lecture (YouTube)
Alan - The worst part is not
Rich - The Universe in a Single Atom by Dalai Lama (Mind and Life Institute)
Vincent
- The Truth about T. Rex by Brian Switek

Listener Pick of the Week

Stephen - International Institute for Species Exploration (Top 10 species choice)

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TWiV 255: Longhorns go viral

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Hosts: Vincent Racaniello and Rich Condit

Guests: Robert Krug and Christopher Sullivan

Vincent and Rich visit the University of Texas at Austin and meet up with Bob and Chris to talk about their work on influenza virus and microRNAs.

Download TWiV 255 (54 MB .mp3, 74 min)

Subscribe (free): iTunesRSSemail

Links for this episode:longhorns-viral

Weekly Science Picks

Rich - Unraveling Bolero
Vincent - New botulinum toxin, DURC implications, and inconvenient truths

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TWiV 254: Ninety-nine macaques on the wall

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Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler

Vincent, Dickson, Alan, and Kathy review clearance of simian immunodeficiency virus infection from macaques by immunization with SIV proteins encoded in a rhesus cytomegalovirus vector.

Download TWiV 254 (69 MB .mp3, 95 min)

Subscribe (free): iTunesRSSemail

Links for this episode:mhc

Weekly Science Picks

Dickson - The Man Who Planted Trees by Jean Giono
Kathy
 - A boy and his atom and Moving Atoms (YouTube)
Alan - It is pitch dark and Get Lamp (YouTube)
Vincent - Who's afraid of peer review? (Science)

Listener Pick of the Week

Maren - Hello Maestro (episodes on YouTube)
Ayesha - Why you don't f****** love science
Jon - A Capella Science (YouTube)

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TWiV 253: I don't know anything about sorghum

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Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

In this second consecutive all-email episode, the complete TWiV team reads questions and comments from listeners about systemic antiviral responses, wild type poliovirus in Israel, Turkish scientists, viral symbiotes, and much more.

Download TWiV 253 (101 MB .mp3, 122 min)

Subscribe (free): iTunesRSSemail

Links for this episode:IMG 5281

Weekly Science Picks

Dickson - HD slow motion montage (YouTube)
Kathy
 - Damselflies and Eyewitness app
Alan - Space weather forecast (YouTube)
Rich - 1984 by George Orwell (Doublethink)
Vincent - PopSci comments off and Why so few women in science?

Listener Pick of the Week

Meika - Flip action roll (YouTube)
CN - Blink: The Power of Thinking without Thinking by Malcolm Gladwell
Bernadeta - Higgs Boson wins Nobel Prize

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TWiV 252: Who read the last email?

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Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

The complete TWiV team reads email from listeners about anti-vaccine activists, a career in microbiology, placentas, a virology textbook, the HeLa cell genome, norovirus, and much more.

Download TWiV 252 (73 MB .mp3, 101 min)

Subscribe (free): iTunesRSSemail

Links for this episode:GlassPolio DesktopBLUE

Weekly Science Picks

Dickson - A Sand County Almanac by Aldo Leopold
Kathy - Noctilucent clouds and aurora over Scotland
Alan - Flu vaccination map
Rich - There's a fly in my urinal
Vincent - Picornaviridae.com

Listener Pick of the Week

Peter - PDB-101

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TWiV 251: Don't kiss the camel

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Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

The complete TWiV crew reviews work on MERS-coronavirus, including serological studies in camels, production of an infectious DNA clone, and identification of an interferon antagonist.

Download TWiV 251 (71 MB .mp3, 98 min)

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Links for this episode:lilian garcia kissing-camel

Weekly Science Picks

Dickson - Scharf Photo
Kathy
 - Blaschka glass models (NY Times, Cornell)
Alan - Digital Public Library of America
Rich - Dengue virus life cycle animation
Vincent - Creative Live

Listener Pick of the Week

John - Last person to get smallpox (NPR)
Peter - SARS documentary (BBC)

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TWiV 250: Wookie viruses

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Hosts: Vincent Racaniello and Robert Garcea

Vincent and Robert recorded this episode at the 53rd ICAAC in Denver, where they talked about polyomaviruses.

Download TWiV 250 (67 MB .mp3, 92 min)

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Links for this episode:

Weekly Science Picks

Robert - The Panic Virus by Seth Mnookin
Vincent - Aliens chestburster behind the scenes

Listener Pick of the Week

Adam - Virology Fact of the Day

Christophe - dr Karl

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TWiV 249: An inordinate fondness for viruses

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Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Vincent, Dickson, Alan and Rich discuss an estimate of the number of different mammalian viruses on Earth.

Download TWiV 249 (66 MB .mp3, 91 min)

Subscribe (free): iTunesRSSemail

Links for this episode:IMG 0636

Weekly Science Picks

Alan - Extreme macrophotography
Dickson - 
Baloney detection kit
Rich -
Mutant silkworms spin colored silk (original article)
Vincent
- FlightRadar24

Listener Pick of the Week

Jenn - Ebola by William Close
Jenn - Eleven Blue Men by Berton Roueche
Todd - Weatherspark and iMap.tv
Nissin -Profiles in Science

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TWiV 248: TWiP infects TWiV

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Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit

Vincent, Dickson, and Rich reveal how experiments with a malaria parasite lead to the introduction of a mammalian retrovirus into birds.

Download TWiV 248 (75 MB .mp3, 103 min)

Subscribe (free): iTunesRSSemail

Links for this episode:journal.pbio.1001641.g001

Weekly Science Picks

Dickson - Google Sky
Rich -
Vanishing of the Bees (see also Bee Apocalypse Now)
Vincent
- Not Exactly Rocket Science

Listener Pick of the Week

Saira - Reproducibility Initiative

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it.

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