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This Week in Virology

twiv

This Week in Virology (TWiV) is a podcast – or netcast, as some prefer to call them, since you don’t need an iPod to listen – about viruses. It was begun in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center. Their goal was to have an informal yet informative conversation about viruses which would be accessible to everyone, no matter what their science background. We wanted to eventually bring other virologists into the conversation, to make it more varied and interesting. Alan Dove, a science writer, joined us late in 2008, and Rich Condit, a poxvirologist, joined in 2009. We’ve had a number of guests on the show and we’re always trying to get more.

Why are we doing this? Dick, Rich, and I have spent our entire academic careers directing research laboratories, so we have a lot of knowledge to share. Plus, we both enjoy teaching. Put those two things together, and you have TWiV. If you want to learn about viruses in a relaxing way, then TWiV is for you.

TWiV 99: ICAAC Boston 2010

On episode #99 of the podcast This Week in Virology, Vincent tours the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), speaking with exhibitors and visitors, including Professors Derek Smith, Michael Schmidt, Frederick Hayden, and Myra McClure.

Host links Vincent Racaniello

twiv99collageLinks for this episode:

Contact

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss by tagging them with 'twiv' here at microbeworld.org.

Download

TWiV #99 (47 MB .mp3, 62 minutes)

 

TWiV 98: Murine musings, electric shirts, and rabid pathologists

On episode #98 of the podcast This Week in Virology, Vincent, Alan, and Rich review the finding of murine leukemia virus-related sequences in the blood of CFS patients and healthy donors, laboratory inventories for wild poliovirus containment, weaving high-performance viral batteries into fabric for the military, and a case of human rabies in Indiana.

Host links Vincent Racaniello, Alan Dove, and Rich Condit

Links for this episode:xmrv_pmrv

Weekly science picks:

Alan - NCBI ROFL
Rich -
The Great Bridge by David McCullough
Vincent - Dr. Rous' Prize-Winning Chicken

Contact

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss by tagging them with 'twiv' here at microbeworld.org.

Download

TWiV #98 (58 MB .mp3, 90 minutes)

TWiV 97: California virology

On episode #97 of the podcast This Week in Virology, Vincent visited Peter Sarnow and Bert Semler during a trip to California, and spoke with them about their work on internal ribosome entry, and the requirement for a cellular microRNA for hepatitis C virus replication.

Host links Vincent Racaniello, Peter Sarnow, and Bert Semler

Links for this episode:sarnow_semler

  • Eukaryotic mRNAs that might contain an IRES (PNAS)
  • Modulation of HCV RNA abundance by a liver-specific microRNA (Science)
  • Viral small RNAs (PLoS Pathogens)
  • Bridging IRES elements to the translation apparatus (Biochim Biophys Acta)
  • A nucleo-cytoplasmic SR protein functions in viral IRES mediated translation (EMBO J)
  • Nuclear vs cytoplasmic routes to IRES mediated translation (Trends in Microbiology)
  • Letter read on TWiV 97

Contact

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss by tagging them with 'twiv' here at microbeworld.org.

Download

TWiV #97 (66 MB .mp3, 91 minutes)

TWiV 96: Making viral DNA

On episode #96 of the podcast This Week in Virology, Vincent, Dickson, and Rich continue Virology 101 with a discussion of how viruses with DNA genomes replicate their genetic information.

Host links Vincent Racaniello, Dickson Despommier, and Rich Condit

Links for this episode:dna replication

Weekly science picks:

Rich - Breast milk sugars give infants a protective coat (NY Times and PNAS article)
Vincent - The Great American University by Jonathan R. Cole

Contact

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss by tagging them with 'twiv' here at microbeworld.org.

Download

TWiV #96 (65 MB .mp3, 90 minutes)

TWiV 95: Does a virus shift in the woods?

On episode #95 of the podcast This Week in Virology, Vincent, Dickson, Alan, and Rich consider the end of the influenza H1N1 pandemic, dengue in Florida, vaccinia virus infection in Brazilian monkeys, and viruses in the faecal microbiota.

Host links Vincent Racaniello, Dickson DespommierAlan Dove, and Rich Condit

Links for this episode:lajeado_tocantins_brazil

Weekly science picks:

Alan - Families Fighting Flu
Rich -
Food, Inc.
Dickson -  Fuel
Vincent - MIT Open Courseware
Michael -  Waiting for Superman and Can Science Feed the World? (Nature)

Contact

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss by tagging them with 'twiv' here at microbeworld.org.

Download

TWiV #95 (68 MB .mp3, 94 minutes)

TWiV 94: XMRV with Dr. Ila Singh

On episode #94 of the podcast This Week in Virology, Vincent, Alan, and Rich speak with Ila Singh about the new human retrovirus XMRV, and how her laboratory is studying its association with prostate cancer and chronic fatigue syndrome.

Host links Vincent Racaniello, Alan DoveRich Condit, and Ila Singh

Links for this episode:ila_singh

Weekly science picks:

Alan - The new Federal Register site (see also regulations.gov)
Rich -
The Florida Museum of Nautural History Butterfly Rainforest
Vincent - JoVE, the Journal of Visualized Experiments

Contact

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss by tagging them with 'twiv' here at microbeworld.org.

Download

TWiV #94 (56 MB .mp3, 77 minutes)

TWiV 93: Our infectious inbox

On episode #93 of the podcast This Week in Virology, Vincent, Alan, and Rich answer listener questions about lab procedures, prokaryotes, endogenous retroviruses, the iPad and teaching, prions, mimivirus, splitting water with viruses, and the polio outbreak in Tajikistan.

Host links Vincent Racaniello, Alan Dove, and Rich Condit

Links for this episode:virus_inbox

Weekly science picks:

Alan - Southern Fried Science
Rich -
Tree of Life web project
Vincent - Dickson Despommier at Big Think

Contact

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss by tagging them with 'twiv' here at microbeworld.org.

Download

TWiV #93 (76 MB .mp3, 105 minutes)

TWiV 92: Live at ASV in Bozeman

Vincent, Rich, Karla, and Marilyn recorded TWiV at the 29th Annual Meeting of the American Society for Virology in Bozeman, where they discussed plant viruses and how they make plants resistant to adverse conditions, and identification of dominant negative drug targets.

Host links Vincent RacanielloRich ConditKarla Kirkegaard, and Marilyn Roosinck

Links for this episode:asv_bozeman

Weekly science picks:

Marilyn - Viruses in the faecal microbiota of monozygotic twins and their mothers (Nature)
Rich -
The Known Universe by the American Museum of Natural History
Vincent - The Red Queen by Matt Ridley (thanks, Jesper!)

Contact

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss by tagging them with 'twiv' here at microbeworld.org.

Download

TWiV #92 (42 MB .mp3, 57 minutes)

TWiV 91; You're an ERVous wreck

On episode #91 of the podcast This Week in Virology, Vincent, Dickson, Alan, Rich and Welkin discuss the nature, origin, and evolution of endogenous retroviruses (ERVs), and the recent finding of endogenous filovirus genomes in mammals.

Host links Vincent Racaniello, Dickson DespommierAlan DoveRich Condit, and Welkin Johnson

Links for this episode:nirvs

Weekly science picks:

Welkin - Advice for a Young Investigator by Santiago Ramon y Cajal
Rich - How microbes define and defend us
Dickson - H1N1 virus lacks 1918 virus killer protein
Alan -
The Xtal Set Society
Vincent - Antibodies and the quest for an AIDS vaccine

Contact

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss by tagging them with 'twiv' here at microbeworld.org.

Download

TWiV #91 (64 MB .mp3, 89 minutes)

TWiV 90: Guano happens

On episode #90 of the podcast This Week in Virology, Vincent, Alan, Rich and Eric discuss identification of viruses in Northeastern American bats, vaccinia virus infection after sexual contact with a military vaccinee, and identification of a new flavivirus from an Old World bat in Bangladesh.

Host links Vincent RacanielloAlan DoveRich Condit, and Eric F. Donaldson

Links for this episode:eric_amy_bat

Weekly science picks:

Eric - Year of Darwin by Sean Carroll
Rich -
March of the Penguins
Alan -
Standing-height desks
Vincent - DengueWatch (thanks Richard!)

Contact

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss by tagging them with 'twiv' here at microbeworld.org.

Download

TWiV #90 (64 MB .mp3, 89 minutes)

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