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This Week in Virology

twiv

This Week in Virology (TWiV) is a podcast – or netcast, as some prefer to call them, since you don’t need an iPod to listen – about viruses. It was begun in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center. Their goal was to have an informal yet informative conversation about viruses which would be accessible to everyone, no matter what their science background. We wanted to eventually bring other virologists into the conversation, to make it more varied and interesting. Alan Dove, a science writer, joined us late in 2008, and Rich Condit, a poxvirologist, joined in 2009. We’ve had a number of guests on the show and we’re always trying to get more.

Why are we doing this? Dick, Rich, and I have spent our entire academic careers directing research laboratories, so we have a lot of knowledge to share. Plus, we both enjoy teaching. Put those two things together, and you have TWiV. If you want to learn about viruses in a relaxing way, then TWiV is for you.

TWiV 132: Virology 911

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Hosts: Hosts: Vincent Racaniello, Rich Condit, Dickson DespommierAlan Dove, and Alfred Sacchetti

Vincent, Rich, Alan, and Dickson speak with Alfred Sacchetti, MD, Chief of Emergency Services at Our Lady of Lourdes Medical Center, about viral infections encountered in the emergency room.

Right-click to download TWiV #132 (48 MB .mp3, 100 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:sacchetti

Weekly Science Picks

Al - The Physics of Superheroes and NKT Watch
Dickson -
Fibonacci Fun by Trudi Hammel Garland and Rachel Gage
RichRetraction Watch
Alan - Neil deGrasse's comments on UFOs, argument from ignorance, and scientific method (YouTube)
Destanie
- Microcosm by Carl Zimmer
Vincent - The intestinal microbiota and viral susceptibility

Listener Pick of the Week

Jim  - Extraordinary Measures

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 131: A REOstat for cancer

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Hosts: Vincent RacanielloAlan Dove, Dickson Despommier, and Brad Thompson

Vincent, Alan, and Dickson chat with Brad Thompson, CEO of Oncolytics Biotech, about using reovirus to treat cancer.

Right-click to download TWiV #131 (42 MB .mp3, 97 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:reovirus_core

Weekly Science Picks

Dickson - Angels and Insects
Alan - Science Buddies
Vincent - Emerging Diseases: The Importance of Early Warning and Surveillance (YouTube)

Listener Pick of the Week

Josh  - Prof. Racaniello's Virology course on iTunes

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 130: Rhino tracking, wrestling pox, and HCV in the crosshairs

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Hosts: Vincent RacanielloAlan Dove, and Rich Condit

Vincent, Alan, and Rich discuss growth in culture of newly identified rhinovirus C, vaccinia transmission among wrestlers and martial artists, and results of phase III clinical trial of boceprevir, a new inhibitor of hepatitis C virus replication.

Right-click to download TWiV #130 (45 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:hrv_c_organ_culture

Weekly Science Picks

Rich - Rock-paper-scissors vs computer (thanks, Megan!)
Alan -
WebCite
Vincent - Edward Jenner Museum (EID)

Listener Pick of the Week

Derek Tolly  - A Paralyzing Fear: The Story of Polio in America (IMDb)

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 129: We've got mail

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Hosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Rich Condit

Vincent, Alan, Dickson and Rich answer listener questions about XMRV, yellow fever vaccine, virus-like particles, West Nile virus, amyotrophic lateral sclerosis and human endogenous retroviruses, multiplicity of infection, and how to make a poxvirus.

Right-click to download TWiV #129 (67 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:rich_unwinds

Weekly Science Picks

Rich - Polyxeni Potter and EID covers
Dickson - American Museum of Natural History
Alan -
Moon Trees (EurekAlert! article)
Vincent - Infection Landscapes

Listener Picks of the Week

Didier  - The Vaccines (MySpace)
/Sven-Urban -
The Science of Discworld by Terry Pratchett
Garren - Omega Tau podcast

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 128: Virologists in the mist

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Hosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Welkin Johnson

Vincent, Alan, Dickson and Welkin review how a virus regulates the severity of mucocutaneous leishmaniasis, virophage control of antarctic algal host-virus dynamics, and human metapneumovirus infection in gorillas.

Right-click to download TWiV #128 (67 MB .mp3, 92 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:gorilla

Weekly Science Picks

Welkin - Walter Reed Collection, University of Virginia
Dickson - Bacteria-phage antagonistic coevolution in soil (Science)
Alan -
The Artful Amoeba
Vincent - Potential bacteriophage applications (Microbe)

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 127: Viruses are no joke

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Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich explore a novel bunyavirus isolated in China, the recent polio outbreak in Republic of the Congo, and cell to cell transmission of a retrovirus by biofilm-like extracellular assemblies.

Right-click to download TWiV #127 (62 MB .mp3, 86 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:cold_chain

Weekly Science Picks

Rich - Should smallpox be destroyed? (Emerging Infectious Diseases)
Alan - Zoology of the Beagle images
Vincent - Vaccines and Your Child by Paul Offit and Charlotte Moser

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 126: Wart's up, doc?

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Hosts: Vincent Racaniello, Dickson DespommierAlan DoveRich Condit, and Michelle Ozbun

On episode #126 of the podcast This Week in Virology, virologist Michelle Ozbun and the TWiV team review the biology of human papillomaviruses.

Right-click to download TWiV #126 (69 MB .mp3, 96 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:ozbun

Weekly Science Picks

Michelle - HIV-1 utilizes chemokine receptor CXCR4 to enter stem cells (PubMed)
Dickson - Bengladesh bans sale of palm sap (NY Times)
Rich - The Medusa and the Snail by Lewis Thomas ("On Warts" - pdf)
Alan - Planting Science - students, teachers, and scientists collaborate on botany experiments
Vincent - CIDRAP - Center for Disease Research and Policy

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 125: TWiV infects FiB

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Hosts: Vincent Racaniello, Dickson DespommierAlan DoveRich Condit, and Marc Pelletier

This Week in Virology and Futures in Biotech join together in a science mashup to talk about a virophage at the origin of DNA transposons, and unintended spread of a recombinant retrovirus.

Right click to download TWiV #125 (59 MB .mp3, 81 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:icosahedron_light


Weekly Science Picks

Marc - JotNot
Dickson - New bunyavirus in China (NEJM)
Rich - Listening to the Deep Ocean Environment (LIDO) recording of the Hatsushima earthquake (ScienceDaily article) - thanks Bridget!
Alan -Walter and Ina: A Story of Love, War, and Science
Vincent - Icosahedral light fixture (thanks, Eric!)


Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 124: Viruses that make you better

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Hosts: Vincent RacanielloDickson DespommierAlan DoveRich Condit, and Grant McFadden

Vincent, Dickson, Alan, Rich, and Grant discuss a tanapoxvirus protein that inhibits tumor necrosis factor, purging tumors with myxoma virus, and destruction of the last known stocks of smallpox virus.

Right click to download TWiV #124 (74 MB .mp3, 103 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:rabbits_myxomatosistrial_wardangisland_1938

Weekly Science Picks

Grant - A Short History of Nearly Everything by Bill Bryson
Dickson - An Inquiry into the Causes and Effects of the Variolae Vaccinae by Edward Jenner
Rich -
Selinah (Topsy Foundation) thanks Meghan!
Alan - Draft report (pdf) on WHO's H1N1 response and NY Times summary
Vincent - 10 stunning science visualizations

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 123: Contaminated prostates, absolute truth, and bleached worms

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Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich talk about XMRV integration sites in prostate tumor DNA, the decline effect and scientific method, and the first virus of Caenorhabditis nematodes.

Right click to download TWiV #123 (67 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:42

Weekly Science Picks

Rich - Einstein: His Life and Universe by Walter Isaacson (Aspen Institute)
Alan - Hi-definition microscopy movies in 3D
Vincent - Stan Maloy interview with Beatrice Hahn on the origins of HIV and malaria

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

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