This Week in Virology

TWiV 222: Jumpin' Jack Flash, it's a GAS GAS GAS

Details

Created on Sunday, 03 March 2013 16:36

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Rich Condit, Dickson Despommier, Alan Dove, and Kathy Spindler

The complete TWiV team discusses the amazing finding that cyclic GMP-AMP synthase is a cytosolic innate immune DNA sensor.

Download TWiV 222 (70 MB .mp3, 97 min)

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Links for this episode:

• Zhijian J. Chen (Wikipedia)
• Sensing the dark side of DNA (Science)
• cGAMP is an endogenous second messenger (Science)
• cGAMP synthase is a DNA sensor (Science)
• Pore-forming toxin (Wikipedia)
• Letters read on TWiV 222

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