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This Week in Virology

twiv

This Week in Virology (TWiV) is a podcast – or netcast, as some prefer to call them, since you don’t need an iPod to listen – about viruses. It was begun in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center. Their goal was to have an informal yet informative conversation about viruses which would be accessible to everyone, no matter what their science background. We wanted to eventually bring other virologists into the conversation, to make it more varied and interesting. Alan Dove, a science writer, joined us late in 2008, and Rich Condit, a poxvirologist, joined in 2009. We’ve had a number of guests on the show and we’re always trying to get more.

Why are we doing this? Dick, Rich, and I have spent our entire academic careers directing research laboratories, so we have a lot of knowledge to share. Plus, we both enjoy teaching. Put those two things together, and you have TWiV. If you want to learn about viruses in a relaxing way, then TWiV is for you.

TWiV 418: Of mice and MERS

The TWiVsters describe a new animal model for MERS coronavirus-induced acute respiratory distress syndrome, produced by CRISPR/Cas9 editing of the mouse gene encoding an ortholog of the virus receptor.

Hosts: Vincent RacanielloDickson DespommierAlan DoveRich Condit, and Kathy Spindler

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Download TWiV 418 (63 MB .mp3, 104 min)

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Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code

This show is sponsored by Drobo, a family of safe, expandable , yet simple to use storage arrays. Drobos are designed to protect your important data forever. This Holiday season give someone a Drobo to keep all their files and memories safe forever. TWiV listeners can save 20% or more off of their purchase of a Drobo 5D, Drobo 5Dt, Drobo 5N, or any 8-drive or 12-drive system at www.drobostore.com by December 31, 2016 using discount code MICROBE20.

Register for ASV 2017 at Madison, Wisconsin

Weekly Science Picks

Alan - Human population through time
Dickson - Every Orbit Cassini Has Taken
Rich - OK GO: Walk Her Walk
Kathy - Medieval Bestiary Online
Vincent - Can You Out-Science an Eighth Grader? and Stitchen Pox

Listener Pick

Hannah - Bioart and Bacteria

Send your virology questions and comments to This email address is being protected from spambots. You need JavaScript enabled to view it.

TWiV 417: O is the loneliest letter

The Fellowship of the Virus trace the early history of HIV in North America, based on genome sequences obtained from late 1970s archival sera, which also reveal that Gaetan Dugas was not Patient Zero.

Hosts: Vincent RacanielloDickson DespommierAlan DoveRich Condit, and Kathy Spindler

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Download TWiV 417 (67 MB .mp3, 111 min)

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Links for this episodeChupacabra padayachee

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Check out the graduate and postdoctoral programs at the Department of Microbiology at the Icahn School of Medicine at Mount Sinai. Deadline for applying to the graduate program is 1 December 2016. For more information about the Department, please visit http://bit.ly/micromssm

Register for the 2017 ASM Grant Writing Online course.

Weekly Science Picks

Alan - VP8SGI
Dickson - New leaf-shaped spider discovered
Rich - Dance of Earth and Venus About the Sun
Kathy - Cultivar Series, Mutatoes, Uli Westphal site
Vincent - Kung Fu Mantis vs Jumping Spider

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TWiV 416: Scattered seeds dormant

The multi-dimensional TWiV-brane brings you the entries in the haiku/limerick contest, and explain how a giant virus infects a host within another host (it has to do with predators!).

Hosts: Vincent RacanielloDickson DespommierAlan DoveRich Condit, and Kathy Spindler

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Download TWiV 416 (77 MB .mp3, 126 min)

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Links for this episodeeucyclops agilis 02 600x600

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Check out the graduate and postdoctoral programs at the Department of Microbiology at the Icahn School of Medicine at Mount Sinai. Deadline for applying to the graduate program is 1 December 2016. For more information about the Department, please visit http://bit.ly/micromssm

Register for the 2017 ASM Grant Writing Online course.

Weekly Science Picks

Alan - Cubes in Space
Dickson - The Architecture of Eden by H. Pearlman and A. Whalley
Rich - Studying the building blocks of life in stereo (original paper)
Kathy - Ancient bottom wipes yield evidence of diseases (original paper)
Vincent - Iguana vs snakes

Send your virology questions and comments to This email address is being protected from spambots. You need JavaScript enabled to view it.

TWiV 415: Ebola pipettors and the philosopher's clone

Jeremy, Aaron, and Ted join the TWiV team to discuss their work on identifying a single amino acid change in the Ebola virus glycoprotein from the West African outbreak that increases infectivity in human cells.

Hosts: Vincent RacanielloAlan DoveRich Condit, and Kathy Spindler

Guests: Jeremy LubanAaron Lin, and Ted Diehl

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Download TWiV 415 (67 MB .mp3, 110 min)

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Links for this episodeGP-A82V Potential Graphical Abstract

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Check out the graduate and postdoctoral programs at the Department of Microbiology at the Icahn School of Medicine at Mount Sinai. Deadline for applying to the graduate program is 1 December 2016. For more information about the Department, please visit http://bit.ly/micromssm

Register for the 2017 ASM Grant Writing Online course.

Weekly Science Picks

Jeremy – Real time tracking of Ebola virus evolution
Ted - The Brain Scoop
Aaron - Kate Rubins sequencing DNA on ISS (video)
Alan – A Sand County Almanac by Aldo Leopold
Rich –  Vendee Globe
Kathy – Axios
Vincent – Vendors from above by Loes Heerinck

Send your virology questions and comments to This email address is being protected from spambots. You need JavaScript enabled to view it.

TWiV 414: Zika in the guys with Diamond

Michael Diamond visits the TWiV studio to talk about chikungunya virus and his laboratory's work on a mouse model of Zika virus, including the recent finding of testicular damage caused by viral replication.

Hosts: Vincent Racaniello

Guest: Michael Diamond

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Download TWiV 414 (50 MB .mp3, 83 min)

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Links for this episodeIMG 3942-300x300

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Check out the graduate and postdoctoral programs at the Department of Microbiology at the Icahn School of Medicine at Mount Sinai. Deadline for applying to the graduate program is 1 December 2016. For more information about the Department, please visit http://bit.ly/micromssm

Register for the 2017 ASM Scientific Writing and Publishing Online Course.

Send your virology questions and comments to This email address is being protected from spambots. You need JavaScript enabled to view it.

TWiV 413: Partnerships not Parachutes

From the EIDA2Z conference at Boston University, Vincent, Alan and Paul meet up with Ralph Baric, Felix Drexler, Marion Koopmans, and Stacey Schultz-Cherry to talk about discovering, understanding, protecting, and collaborating on emerging infectious diseases.

Hosts: Vincent Racaniello, Alan Dove, and Paul Duprex 

Guests: Ralph BaricFelix DrexlerMarion Koopmans, and Stacey Schultz-Cherry

 

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This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

This episode is  brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Check out the graduate and postdoctoral programs at the Department of Microbiology at the Icahn School of Medicine at Mount Sinai. Deadline for applying to the graduate program is 1 December 2016. For more information about the Department, please visit http://bit.ly/micromssm

Send your virology questions and comments to This email address is being protected from spambots. You need JavaScript enabled to view it.

 

TWiV 412: WO, open the borders and rig the infection

The TWiVome reveal the first eukaryotic genes found in a bacteriophage of Wolbachia, and how DNA tumor virus oncogenes antagonize sensing of cytoplasmic DNA by the cell.

Hosts: Vincent RacanielloAlan DoveRich Condit, and Kathy Spindler

Guest: Mark Fuccio

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Download TWiV 412 (73 MB .mp3, 121 min)

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Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Weekly Science Picks

Mark - EFN Enterprise Futures Network and Mission Log Podcast
Alan - 
2016 Wildlife Comedy Photography
Rich
 -  ZuTA, portable robotic printer
Kathy - How LEGO help blind people see
Vincent - 
Airplane photos of Mike Kelley

Listener Pick

Hannah - Frozen Flow Glass (Instagram)

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TWiV 411: Chicken runs

The TWiVeroos examine a reverse spillover of Newcastle disease virus vaccines into wild birds, and identification of a protein cell receptor for murine noroviruses.

Hosts: Vincent RacanielloAlan DoveRich Condit, and Kathy Spindler

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 Download TWiV 411 (59 MB .mp3, 95 min)

Subscribe (free): iTunesRSSemail

Become a patron of TWiV!

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Weekly Science Picks

Alan - Braincraft
Rich
 -  Now is the Greatest Time to Be Alive
Kathy - CRISPR/Cas9 by A Capella Science
Vincent - 
Microbes After Hours: The Necromicrobiome

Listener Pick

Jolene - Chalk Talk Science by Dennis Mangan

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TWiV 410: Hurricane Zika

Sharon and Scott join the TWiV team to talk about their work on dengue antibody-dependent enhancement of Zika virus infection, and identifying the virus in mosquitoes from Miami.

Hosts: Vincent RacanielloAlan DoveRich Condit, and Kathy Spindler 

Guests: Sharon Isern and Scott Michael

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Download TWiV 410 (73 MB .mp3, 121 min)

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Links for this episodeSharon Isern Scott Michael

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Weekly Science Picks

Sharon - Zika virus comics and cartoons and Florida weekly arbovirus reports
Scott - Real-time tracking of Zika virus evolution
Alan - Evolution of antibiotic resistance on a mega plate
Rich
 -  Windytv
Kathy - Zika virus map and timeline
Vincent - 
Ohsumi Nobel advanced information and HR 5325 funding breakdown

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TWiV 409: A Nef is enough

Jeremy joins the TWiVeroids to tell the amazing story of how the function of the HIV-1 protein called Nef was discovered and found to promote infection by excluding the host protein SERINC from virus particles.

Hosts: Vincent RacanielloDickson DespommierAlan DoveRich Condit, and Kathy Spindler

Guest: Jeremy Luban

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 Download TWiV 409 (75 MB .mp3, 124 min)

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Links for this episodeIMG 3813

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Weekly Science Picks

Alan - Migration in Motion
Dickson - Beautiful Chemistry
Rich - XKCD Timeline of Earth Temperature
Kathy
 -  Vaccine Heroes from Vaccine Education Center
Jeremy - CIDRAP posters and Demon in the Freezer
Vincent - 
People Peas and Pathogens

Listener Picks

Matlock - Science isn't broken

Send your virology questions and comments to This email address is being protected from spambots. You need JavaScript enabled to view it.

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