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This Week in Microbiology

vincentThis Week in Microbiology (TWiM) is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.

As a science Professor at Columbia University, Racaniello has spent his academic career directing a research laboratory focused on viruses. His enthusiasm for teaching inspired him to reach beyond the classroom using new media. TWiM is for everyone who wants to learn about the science of microbiology in a casual way.

While there are no exams or pop quizzes, TWiM does encourage interaction with the audience via comments on specific episodes (below), vial email and voicemail at 908-312-0760. Listeners can also use MicrobeWorld to suggest topics for the show by submitting articles or papers to the site and tagging them with "TWiM". Each week Racaniello will view the tagged content and select items for discussion.

TWiM co-hosts include Elio SchaechterMichael Schmidt, and Michele Swanson.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

TWiM #133: Right under our noses

Insight into the biology of rhinovirus C from cryo-electron microscopy, and a novel antibiotic from a commensal bacterium that grows in the human nose, from the doctors of TWiM.

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt.

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Right click to download TWiM#133 (44.5 MB .mp3, 61 minutes).nose

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it.  

TWiM #132: Bacteria learn long division

Vincent, Elio, and Michele present cell division by longitudinal scission in an insect symbiont, and thermally activated charge transport in microbial nanowires.

Read more: TWiM #132: Bacteria learn long division

TWiM 131: Mice behaving badly

Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.

Hosts: Vincent Racaniello and Michael Schmidt

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Right click to download TWiM#131 (60 MB .mp3, 82 minutes).

Subscribe to TWiM (free) on iTunesStitcherRSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episodetwim 131

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

Send your microbiology questions and comments (email or mp3 file) to  This email address is being protected from spambots. You need JavaScript enabled to view it.

TWiM #130: Interkingdom interactions at ASM Microbe

The TWiMers get together at ASM Microbe 2016 in Boston to speak with David and Vanessa to talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt.

Guests: David S. Schneider and Vanessa Sperandio

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Right click to download TWiM#130 (35.5 MB .mp3, 77 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

Send your microbiology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it.  

TWiM #129: Dried and wrinkled, smooth and mucoid

The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.

Image (right): Etest used to determine the minimum inhibitory concentration of an antibiotic for a particular bacterium.

Hosts: Vincent RacanielloMichael Schmidt, and Michele Swanson.

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Right click to download TWiM#129 (51 MB .mp3, 70.5 minutes).Etest

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

Send your microbiology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it.  

TWiM #128: A moonlighting phage protein

A eukaryote without a mitochondrion, and using a phage enzyme to eliminate intracellular bacteria are two topics discussed by the TWiMers on this episode.

Image (right): An entry in the ASM Agar Art Contest which bears an uncanny resemblance to one of the TWiM hosts.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt.

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Right click to download TWiM#128 (37.5 MB .mp3, 77.5 minutes).TWiV agar art

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

Send your microbiology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it.  

TWiM #127: Subway Snowblowers and Men in Black

The TWiM team explores microbes in snowblower vents on the ocean floor, and cleavage of antibody molecules by a Mycoplasma protease.

Image (right): Photograph of the ‘Subway’ snowblower vent on the sea floor at Axial Seamount, Juan de Fuca Ridge. Visible are white ‘snow’ in the vent and orange floc on the seafloor. Credit: Canadian Scientific Submersible Facility and the University of Washington.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt.

snowblower vent800

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Right click to download TWiM#127 (40 MB .mp3, 54.5 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Grant Writing Course

Send your microbiology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it.  

TWiM #126: I’m not scared of zebrafish and mice and bears (oh my!)

The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.

Image: Bright-field (top) and fluorescent (bottom) images of zebrafish embryos infected with E. coli strain F11. Epithelial cells are green. Arrowheads mark protrusion caused by infection.

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.

zebrafish

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Right click to download TWiM#126 (48.5 MB .mp3, 67 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Send your microbiology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it.  

TWiM #125: A minimal cell operating system

A deep sequencing study of commercially available probiotics, and design and synthesis of a minimal bacterial genome are the topics tackled by Vincent, Michael, and Michele on this episode of TWiM.

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.

dividing M mycoides

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Right click to download TWiM#125 (42 MB .mp3, 58 minutes).

Image: Negatively stained transmission electron micrographs of dividing M. mycoides JCVI-syn1. Cells were stained using 1% uranyl acetate on pure carbon substrate and visualized using a transmission electron microscope.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Send your microbiology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 

TWiM #124: Fungal pirates

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.

Vincent, Michael, and Michele reveal how a fungal protease blunts the innate immune response and promotes pathogenicity. 

Read more: TWiM #124: Fungal pirates

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