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New vaccines against an old disease: brucellosis

Brucellosis is a worldwide extended infectious disease of livestock (sheep, goats, cattle, cows, pigs, …) and remains one of the most common zoonotic infections, with more tan 500,000 new human cases worldwide every year. Control and eradication of brucellosis requires the use of animal vaccines... Read More

Introducing the Thanatomicrobiome

In a healthy adult human body, most internal organs such as the brain, spleen, liver, and heart are devoid of microorganisms because the immune system keeps them in check. After human host death, however, the immune system falters and microorganisms proliferate throughout the body beginning in ... Read More

Graphic Warnings: Ebola Posters Keep The Virus On People's Minds

The campaign is called "Kick Back Ebola." But the posters pack a punch.

Sierra Leone has reported over 700 suspected Ebola cases, more than any other country this year. To help stop the outbreak, health workers have put up Ebola awareness signs all over Sierra Leone's seaside capital of Freet... Read More

Scientists Choose Sides In Safety Debate Over Lab-Made Pathogens

A smoldering debate about whether or not researchers should ever deliberately create superflu strains and other risky germs in the interest of science has flared once again.

Proponents of the work say that in order to protect the public from the next naturally occurring pandemic, they have to... Read More

Asian Tiger Mosquito Could Expand Painful Caribbean Virus into U.S.

Rapid expansion of this species, which is more aggressive than the species that is now spreading chikungunya into the Caribbean, is worrying scientists.

In the past few months, passengers at North American airports have been warned that travel to the Caribbean might result in an unwanted souv... Read More

Harnessing the Power of Bacteria’s Sophisticated Immune System

Bacteria’s ability to destroy viruses has long puzzled scientists, but researchers at the Johns Hopkins Bloomberg School of Public Health say they now have a clear picture of the bacterial immune system and say its unique shape is likely why bacteria can so quickly recognize and destroy their as... Read More

Ebola Protein Blocks Early Step in Body’s Counterattack on Virus

One of the human body’s first responses to a viral infection is to make and release signaling proteins called interferons, which amplify the immune system response to viruses. Over time, many viruses have evolved to undermine interferon’s immune-boosting signal, and a new study describes a mecha... Read More

Mouth Bacteria Can Change Its Diet, Supercomputers Reveal

Bacteria inside your mouth drastically change how they act when you're diseased, according to research using supercomputers at the Texas Advanced Computing Center (TACC). Scientists say these surprising findings might lead to better ways to prevent or even reverse the gum disease periodontitis, ... Read More

Gut Flora Influences HIV Immune Response

Normal microorganisms in the intestines appear to play a pivotal role in how the HIV virus foils a successful attack from the body’s immune system, according to new research from Duke Medicine.

The study, published Aug. 13, 2014, in the journal Cell Host & Microbe, builds on previous work fro... Read More

Scientists boost potential of passive immunization against HIV

Scientists are pursuing injections or intravenous infusions of broadly neutralizing HIV antibodies (bNAbs) as a strategy for preventing HIV infection. This technique, called passive immunization, has been shown to protect monkeys from a monkey form of HIV called simian human immunodeficiency vir... Read More

Watch This Week in Virology Episode 300 Live from ASM HQ Aug 26 7 pm ET

This Week in Virology, the podcast about viruses, celebrates its 300th episode on Tuesday, August 26, 2014 with a live recording at the Washington, DC headquarters of the American Society for Microbiology. This special episode w... Read More

Treating Cancer With Bacteria Shows Real Promise

n a groundbreaking study, researchers say injecting bacteria into a tumor helped shrink it.

Bacteria are generally considered more foe than friend, but that may change, if results from a pioneering study are confirmed.

Reporting in the journal Science Translational Medicine, scientists led... Read More

Pictures Considered #19. The Basal End of Bacterial Flagella

The end of bacterial flagella that is near the cell is a marvel of mechanical miniaturization — a molecular wheel that turns, just like the axle of a car. The assembly consists of a stator, the part that holds it in place, and a rotor, the part that turns. The rotor is a beautifully complex str... Read More

TWiV 298: MV-NIS de myelo

The TWiV gang answers follow-up questions about the Ebola virus outbreak in West Africa, then discuss treatment of  disseminated multiple myeloma with oncolytic measles virus.


Hosts: Vincent Racaniello... Read More

In Hunt For New Antibiotics, Scientists Look At Bacteria In Insects' Stomachs

Pampering leafcutter ants with fragrant rose petals and fresh oranges may seem an unlikely way to rescue modern medicine, but scientists at a lab in eastern England think it's well worth trying.

As the world cries out for new antibiotics, researchers at the John Innes Center (JIC) in Norwich ... Read More

BacterioFiles 179 - Functionless Phages Feel Fatiguing

 This episode: Defective phages in bacterial genomes can still have burdensome effects! Why do the bacteria keep them around?


(10.4 MB, 11.3 minutes)


Show notes: 
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Early antibiotic exposure leads to lifelong metabolic disturbances in mice

Antibiotic exposure during a critical window of early development disrupts the bacterial landscape of the gut, home to trillions of diverse microbes, and permanently reprograms the body’s metabolism, setting up a predisposition to obesity, according to a new study. Moreover, the research shows t... Read More

Rethinking The Origin of Species: Discover Magazine Features The Speciation Microbiome Project

From Discover: "Scientists have long known of the important roles played by the microbes on and in our bodies — our microbiomes. These little guys outnumber our own cells 10 to 1, and they help regulate everything from the energy we get out of food to the health of our immune systems. Now, scien... Read More

Zombie ant fungi manipulate hosts to die on the 'doorstep' of the colony

A parasitic fungus that must kill its ant hosts outside their nest to reproduce and transmit its infection, manipulates its victims to die in the vicinity of the colony, ensuring a constant supply of potential new hosts, according to researchers at Penn State and colleagues at Brazil's Federal U... Read More

New discovery: Microbes can create dripstones

According to new research humble, microscopic organisms can create dripstones in caves. This illustrates how biological life can influence the formation of Earth’s geology - and the same may be happening right now on other planets in space.

According to traditional textbooks dripstones are cr... Read More
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