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TWiP 83 letters

Robin writes:

Malaria: shaking chills & fever (followed by sweats, not specifically mentioned in this case), is a characteristic of malaria that is unforgettable once one has had it (I had malaria four times).

Thick blood smears is de rigueur.
So... Read More

TWiV 319: Breaking breakbone

The TWiVers review the outcomes of two recent phase 3 clinical trials of a quadrivalent dengue virus vaccine in Asia and Latin America.

Hosts: Vincent Racaniello Read More

Birds that eat at feeders more likely to get sick, spread disease

BLACKSBURG, Va., Sept. 17, 2015 - Wild songbirds that prefer to eat at bird feeders have an increased risk of acquiring a common eye disease. In turn, these birds also spread the disease more quickly to their flock mates, according to an international research team led by Virginia Tech scientist... Read More

TWiV 312: She sells B cells

The TWiVbolans discuss the finding that human noroviruses, major causes of gastroenteritis, can for the first time be propagated in B cell cultures, with the help of enteric bacteria.

Hosts:  Read More

Infection with multiple HIV-1 variants leads to poorer clinical outcomes

HIV-1 infection with multiple founder variants points to poorer clinical outcomes than infection with a single variant, according to a paper published today in the journal Nature Medicine. Read More

TWiV 314: Einstein goes viral

Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells.

Host:  Read More

TWiM 100 Letters

Matt Daugherty writes:

I just listened to the latest TWiM. Thanks for covering our horizontal gene transfer paper! It was great to hear you all talk about it and give your thoughts.

With regards to the selective pressure for retention of the Dae’s in genomes o... Read More

TWiP 82 letters

Allan writes:

Dear Vincent, Dickson and Daniel,

I like your idea of a TWIP coffee mug prize (or maybe a mug discount).

In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More

TWiP 79 letters

Jesse writes:

Doctors TWiP,

I came across this paper and thought it sounded interesting for a discussion on TWiP:

Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection
Read More

TWiV 321: aTRIP and a pause

Paul Duprex joins the TWiV team to discuss the current moratorium on viral research to alter transmission, range and resistance, infectivity and immunity, and pathogenesis.

Hosts: Vincent Racaniel... Read More

TWiP 91 letters


Heather writes:

Dear Dr.s R, D & G,

I really hate to criticize learned professors, especially my elders. I suspect I may be being overly - sensitive or perhaps it is a cultural difference. However, the "over-talking" is decreasing the qualit... Read More

Antitumor Drug Can be produced in Laboratory Now

BOC Sciences-Scientists have successfully found a way for producing an important cancer drug ingredient in lab recently, which may bring a decrease to the cost of the related drug as its material could only be got from a plant which rarely exists. Read More

TWiM 103 Letters

Bailey writes:

Hey Vincent, Elio, Michele and Michael!

I'm a first year microbiology graduate student at UC Berkeley and an avid listener of twim. Elio's snippet from the most recent podcast reminded me of a personal anecdote that might be useful to share with... Read More

TWiM 93 Letters

David writes:

Why not eat locusts? Assuming you can find any fuel to cook em, and apart from deficiency illnesses, I've always wondered why people didn't hunker down and harvest them for emergency food. Did original peoples endure swarms by eating them? Did Euro food ... Read More

TWiV 309: Ebola email

The TWiVocytes answer questions about Ebola virus, including mode of transmission, quarantine, incubation period, immunity, and much more.

 Hosts: Vincent Racaniello Read More

TWiV 325: Wildcats go viral

Hosts: Vincent Racaniello

Guests: Rollie Clem and Lorena Passarelli

{audio... Read More

TWiV 332: Vanderbilt virology

Host: Vincent Racaniello

Guests: Seth BordensteinJames Crowe... Read More


A new study will explore whether living with a dog encourages the growth of positive microorganisms in the human gut—enough to improve physical and mental health in older adults. Read More

Many physicians overestimate ability to assess risk of Ebola, study finds

Researchers at Massachusetts General Hospital have found that the physicians least likely to encounter the infectious Ebola virus tend to be overly cautious even with low-risk patients. Read More

TWiP 96: Salivary pharmacopeia

The TWiPanosomes solve the case about the Young Woman who Went to Belize, and relate how sandfly saliva skews the immune response and increases risk of cutaneous leishmaniasis.

Hosts:  Read More

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