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What Gut Bacteria Might Have To Do With Colorectal Cancer Risk

While genetics likely play a role in some instances of colorectal cancer, a new study in mice suggests gut bacteria could also influence development of intestinal tumors. Researchers from the Icahn School of Medicine at Mount Sinai found that giving antibiotics to mice to disrupt their microbial... Read More

Gonorrhea Infections Start From Exposure To Seminal Fluid

Researchers have come a step closer to understanding how gonorrhea infections are transmitted. When Neisseria gonorrhoeae, the bacteria responsible for gonorrhea, are exposed to seminal plasma, the liquid part of semen containing secretions from the male genital tract, they can more easily move ... Read More

2,300 tubes containing SARS virus samples missing in France

A major French biomedical research body, the Pasteur Institute, have launched an investigation into the disappearance of some 2,300 test tubes containing samples of the SARS virus. The loss was discovered during an inventory.

The Pasteur Institute filed a so-called 'complaint against X' on Mo... Read More

How Ebola Blindsides the Body's Defenses

Researchers often describe the battle between the Ebola virus and the humans it occasionally infects as a race—one that people win only if their immune systems manage to pull ahead before the virus destroys too many of their internal defenses. What they may not know is that the virus is a cheat.... Read More

Bacterial Nanowires: Not What We Thought They Were

New videos of morphing bacteria reveal that the strange, distinguishing features of so-called “electric bacteria” aren’t quite what they at first appeared to be.

For the past 10 years, scientists have been fascinated by a type of “electric bacteria” that shoots out long tendrils like electric... Read More

TWiM 87 Letters

Varun writes:


Greetings TWiM Profz,


As a perso... Read More

A WORD on the constraints of influenza virus evolution

Evolution proceeds by selection of mutants that arise by error-prone duplication of nucleic acid genomes. It is believed that mutations that are selected in a gene are dependent on those that have preceded them, an effect known as epistasis. Analysis of a sequence of changes in the influenza vir... Read More

New drugs for bad bugs

Washington University in St Louis chemist Timothy Wencewicz says we’ll stay ahead of antibiotic resistance only if we find drugs with new scaffolds, or core chemical structures. One promising candidate, an antibiotic made by a bacterium than infects plants, caught his attention because it contai... Read More

Battling Infection With Microbes

The human relationship with microbial life is complicated. At almost any supermarket, you can pick up both antibacterial soap and probiotic yogurt during the same shopping trip. Although there are types of bacteria that can make us sick, Caltech professor of biology and biological engineering Sa... Read More

BacterioFiles 201 - Plastic-Producing Prokaryote Process

This episode: Bacteria from wastewater treatment sludge can produce lots of biodegradable plastic!


(7.1 MB, 7.75 minutes)


Show notes: 
Jour... Read More

Arctic bacteria gene swap to detoxify mercury

On the list of substances you really don’t want to mess with, elemental mercury is pretty high up. Inhalation or absorption of the volatile metal can quickly lead to irreversible poisoning. Unfortunately, Hg is also a hallmark of industrial society.....Mercury-resistant bacteria carry a collecti... Read More

The Ebola Outbreak: 'A Dress Rehearsal For The Next Big One'

Until this year, the world had recorded 1,640 deaths from Ebola since the virus was discovered in 1976.

Then Ebola appeared in West Africa.

So far this year, 887 people have died of Ebola in West Africa, the World Health Organization said Monday.

To put that into perspective, more than ... Read More

TWiP 77 letters

Andy writes:


Dear Professors,


I have been following TWIP for several years. I am a software engineer and parasitology is only an avocation. As an undergraduate in the early 80's I discovered my love of history of science and ecology, although I continued the p... Read More

TWiV 299: Rocky Mountain virology

Vincent visits the Rocky Mountain Laboratories in Hamilton, Montana and speaks with Marshall, Sonja, and Byron about their work on tick-born flaviviruses, innate immunity, and prion diseases.


Host: Vincent ... Read More

TWiV 314: Einstein goes viral

Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells.


Host:  Read More

When Will We Have a Vaccine for Ebola Virus?

The latest outbreak of Ebola virus in west Africa is the worst ever—as of Monday, it had infected more than 1,200 people and claimed at least 672 victims since this spring. Guinea, Liberia and Sierra Leone all have confirmed cases. An official at Doctors Without Borders has declared the outbreak... Read More

Stanford bioengineer develops a 50-cent paper microscope

The Foldscope is a fully functional microscope that can be laser- or die-cut out of paper for around 50 cents.

This bookmark-sized microscope can be assembled in minutes, includes no mechanical moving parts, packs in a flat configuration, is extremely rugged and can be incinerated after to s... Read More

Protein's "hands" enable bacteria to establish infection, research finds

When it comes to infecting humans and animals, bacteria need a helping hand.

Kansas State University biochemists have found the helping hand: groups of tiny protein loops on the surface of cells. These loops are similar to the fingers of a hand, and by observing seven individual loops on the ... Read More

New Springtime Flu Strain Going Around New York

Thought you only had to deal with allergies these days? Well, maybe you've noticed some friends or work colleagues calling in sick lately—that may be because there's another flu strain making the rounds.

According to the Centers for Disease Control, influenza B is accounting for 55% of all vi... Read More

New research shows that bacteria survive longer in contact lens cleaning solution than previously thought

Each year in the UK, bacterial infections cause around 6,000 cases of a severe eye condition known as microbial keratitis - an inflammation and ulceration of the cornea that can lead to loss of vision. The use of contact lenses has been identified as a particular risk factor for microbial kerati... Read More
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