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Viral variation in single cells

It is well known that virus populations display phenomenal diversity. Virus populations are dynamic distributions of nonidentical but related members called a quasispecies. This diversity is restricted in single cells, but is restored within two infectious cycles. Read More

Community ecology can advance the fight against infectious diseases

Despite continued medical advances, infectious diseases kill over 10 million people worldwide each year. The ecological complexity of many emerging disease threats--interactions among multiple hosts, multiple vectors and even multiple parasites--often complicates efforts aimed at controlling dis... Read More

Interrupting the transmission cycle: A protein required for dengue virus infection of mosquitoes

There is currently no approved specific treatment or vaccine for dengue fever, and an estimated 2 billion people are at risk for being bitten by Aedes mosquitoes and infected with the dengue virus (DENV). A study published on October 22nd in PLOS Pathogens introduces a candidate target for a tra... Read More

HIV cure research: NIH scientists create 2-headed protein to deplete HIV reservoir

Scientists at the National Institutes of Health (NIH) have created a protein that awakens resting immune cells infected with HIV and facilitates their destruction in laboratory studies. The protein potentially could contribute to a cure for HIV infection by helping deplete the reservoir of long-... Read More

TWiM #132: Bacteria learn long division

Vincent, Elio, and Michele present cell division by longitudinal scission in an insect symbiont, and thermally activated charge transport in microbial nanowires.


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Link between small mammals and evolution of hepatitis A virus to humans discovered

Researchers at the University of North Carolina at Chapel Hill (UNC-Chapel Hill) are part of an international team led by the University of Bonn, Germany, who have found a link between the origin of hepatitis A virus (HAV) and small mammals. With the emergence of Ebola virus from bats and hantav... Read More

'Clever adaptation' allows yeast infection fungus to evade immune system attack

Johns Hopkins Bloomberg School of Public Health researchers say they have discovered a new way that the most prevalent disease-causing fungus can thwart immune system attacks. Read More

Bat SARS-like coronavirus: It’s not SARS 2.0!

A study on the potential of SARS-virus-like bat coronaviruses to cause human disease has reawakened the debate on the risks and benefits of engineering viruses. Let’s go over the science and then see if any of the criticisms have merit. Read More

Tripped up by a bug: Infection may cause falls, especially in older people, study suggests

SAN DIEGO - People who end up in the emergency room because of a fall often are tripped up by an infection, rather than a loose throw rug or poor eyesight, suggests a study being presented at IDWeek 2015™. Read More

Decontamination Exterminates Antibiotic Resistant Bacteria from Pig Farm

Washington, DC – September 4, 2015 - Decontamination protocols eradicated both methicillin-resistant Staphylococcus aureus (MRSA) and antibiotic resistant, pathogenic intestinal bacteria, the Enterobacteriaceae, from a pig farm. The research appears online September 4th in ASM’s journal Applied ... Read More

Role of breast cell infection in flu transmission between mothers and breast-feeding ferrets

Influenza is known as an infectious respiratory disease, but a study published on October 8th in PLOS Pathogens suggests that infected cells in breast tissues could play a role in virus transmission from mothers to breast-feeding infants and vice versa using a ferret model. Read More

MMP #12: Hydrogen from ground rocks can furnish microbial ecosystems with energy to drive growth.

Host: Jeff Fox with special guest, Jon Telling.


Jon Telling of Bristol University in Bristol, United Kingdom talks with Jeff Fox about his findings suggesting that the grinding of glaciers over rocks can liberate hydrogen, which, in turn, drives the growth of methanogens within microb... Read More

3 ANTIBIOTICS GANG UP TO KILL DEADLY STAPH

As a trio, three antibiotics that aren’t individually effective against a drug-resistant staph infection killed the deadly pathogen in test tubes and mice. Read More

Flu vaccine reduces hospitalizations and deaths among nursing home residents

When the influenza vaccine is well matched to the prevailing strains of flu in a given season, patients in nursing homes are significantly less likely to be hospitalized or to die of pneumonia and other influenza related causes. The finding comes from a study of more than 1 million Medicare fee-... Read More

Guinea reports Ebola-free week, but Sierra Leone has 5 cases

For the first time in more than a year, Guinea passed a week without a new lab-confirmed Ebola case, but the news out of West Africa last week was tempered by a flare-up of activity in Sierra Leone, the World Health Organization (WHO) reported today in its latest update. Read More

BacterioFiles 261 - Pilfered Parasitoid Proteins Protect Prey

This episode: Viruses domesticated by parasitoid wasps have transferred wasp genes to caterpillar victims, allowing them to survive deadly infections from other viruses! This means that Monarch butterflies are effectively naturally Genetically Modified Organisms (GMOs).


(13.8 MB, 15 m... Read More

Gerilizumab IL-6 is Put into Human Trial for Rheumatoid Arthritis

BOC Sciences-Recently, a biotechnology company announced that gerilizumab IL-6 as a drug for rheumatoid arthritis was under trial in healthy people. Once the safety is proved in human trial, gerilizumab will be a better alternative for rheumatoid arthritis both in effect and cost. Read More

Hibernating bats mount a partial immune response against white nose fungus

White-nose syndrome (WNS), an invasive skin infection caused by the Pseudogymnoascus destructans (Pd) fungus has killed millions of bats since it was first seen in North America in 2007. A analysis of gene expression in hibernating bats infected with the destructive fungus published on October 1... Read More

Infectious diseases bring millions of elderly to emergency departments each year

Investigators estimate that during 2012, there were more than 3.1 million emergency department visits for infectious diseases among elderly US adults. Read More

Strategies to decrease bacterial colonization

Among the bacterial infections that are most difficult to treat, chronic infections associated with bacterial biofilms are one of the most hazardous. Bacterial biofilms are densely packed communities of microbial cells surrounded with secreted polymers. In her doctoral thesis, chemist Shoghik Ha... Read More
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