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One in four hepatitis C patients denied initial approval for drug treatment

New Haven, Conn. -- Nearly one in four patients with chronic hepatitis C (HCV) are denied initial approval for a drug therapy that treats the most common strain of the infection, according to a Yale School of Medicine study. Read More

Stanford researchers genetically engineer yeast to produce opioids

For thousands of years, people have used yeast to ferment wine, brew beer and leaven bread. Now researchers at Stanford have genetically engineered yeast to make painkilling medicines, a breakthrough that heralds a faster and potentially less expensive way to produce many different types of pla... Read More

BacterioFiles 210 - Archaea Acquired Alternative Abilities

This episode: Genes taken from bacteria may have been important for the evolution of distinct groups of archaea!


(7.4 MB, 8 minutes)


Show notes: 
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Prion trials and tribulations: Finding the right tools and experimental models

Prions are fascinating, enigmatic, and might teach us not only about rare prion diseases like Creutzfeld-Jakob disease, mad cow disease, or scrapie, but also about other more common neurodgenerative diseases. Two studies published on July 2nd in PLOS Pathogens report progress with novel tools an... Read More

The Mechanism of Aging May Be Found By Scientists

BOC Sciences-Anti-aging has long been a research and study subject, but few breakthrough has been made since no original reason was found for this normal body change with age increasing. Recently scientists from TSRI may find the underlying reason for aging diseases. Read More

Pitt researchers to monitor resistance to HIV drugs in Africa

PITTSBURGH, Aug. 3, 2015 - Infectious diseases researchers from the University of Pittsburgh School of Medicine are leading a five-year, $5 million initiative to monitor drug resistance during the rollout of HIV prevention drugs in sub-Saharan Africa. Read More

An Ebolavirus vaccine in Africa

An Ebolavirus vaccine has shown promising results in a clinical trial in Guinea. This vaccine has been in development since 2004 and was made possible by advances in basic virology of the past 40 years. Read More

Detecting HIV diagnostic antibodies with DNA nanomachines

New research may revolutionize the slow, cumbersome and expensive process of detecting the antibodies that can help with the diagnosis of infectious and auto-immune diseases such as rheumatoid arthritis and HIV. An international team of researchers have designed and synthetized a nanometer-scale... Read More

1977 H1N1 influenza virus is not relevant to the gain of function debate

The individuals who believe that certain types of gain-of-function experiments should not be done because they are too dangerous (including Lipsitch, Osterholm, Wain-Hobson,) cite the 1977 influenza virus H1N1 strain as an example of a laboratory accident that has led to a global epidemic. A new... Read More

New understanding of genetic susceptibility to infections by Candida and Mycobacterium

The discovery of bi-allelic mutations in RORC in patients with candidiasis and mycobacteriosis revealed the pivotal role of RORC in mucocutaneous immunity to Candida and in systemic immunity to Mycobacterium in humans. Read More

HIV testing among older adults is declining, despite CDC recommendation

Researchers led by the UCLA Fielding School of Public Health examined HIV testing trends among adults ages 50 through 64 both before and after 2006, when the Centers for Disease Control and Prevention (CDC) recommended that most doctors automatically screen all patients for HIV regardless of whe... Read More

New method to treat antibiotic resistant MRSA: Bacteriophages

MRSA is bad news. If you've never heard of it, here's what you need to know: It's pronounced MER-suh, it's a nasty bacterial infection and it can cause serious disease and death. Read More

Researchers Find Novel Signature in the Brains of Children with Cerebral Malaria: Disease exacerbated by HIV

Washington, DC - September 22, 2015 - Cells associated with inflammation and blood clotting accumulate in the brain blood vessels of children affected by a potentially fatal form of malaria called cerebral malaria (CM), potentially contributing to the disease process, an international team of re... Read More

Brown University to help Ghana build HIV, TB research capacity

PROVIDENCE, R.I. [Brown University] -- Tuberculosis is the leading cause of death among HIV-positive Ghanaians, with one study blaming TB for 57 percent of HIV-related deaths in the mid-sized West-African nation. To tackle the problem, a partnership between Brown University and the University of... Read More

New Use for Well-known Algae

Shock! Horror! Some treasured molecular paleoenvironmental tools of organic biogeochemists—namely the alkenones, an esoteric group of long-chained compounds made by aquatic microalgae—are being put forward by O’Neil et al.1 as candidates for conversion to jet fuel on an industrial scale! (See... Read More

Chickenpox vaccination does increase shingles cases, but mainly in young adults

Vaccinating one-year-olds against chickenpox could temporarily nearly double the incidence of shingles in the wider population, but in younger adults than previously thought. Read More

How I Became a Microbial Supremacist...

In this third installment of my "Mu-Tube" video series about microbiology and microbiology education, I discuss how I was initially labeled a "microbial supremacist" as a joke, and then embraced the title with enthusiasm. I also show many examples of the microbiology-related art I use to encour... Read More

Virus in cattle linked to human breast cancer

BERKELEY -- A new study by University of California, Berkeley, researchers establishes for the first time a link between infection with the bovine leukemia virus and human breast cancer. Read More

Meningitis model shows infection's sci-fi-worthy creep into the brain

DURHAM, N.C. - Scientists at Duke Medicine are using transparent fish to watch in real time as Cryptococcal meningitis takes over the brain. The resulting images are worthy of a sci-fi movie teaser, but could be valuable in disrupting the real, crippling brain infection that kills more than 600,... Read More

Discovery points to a new path toward a universal flu vaccine

Flu vaccines can be something of a shot in the dark. Not only must they be given yearly, there's no guarantee the strains against which they protect will be the ones circulating once the season arrives. Read More
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