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Following Maternal Transmission, Group B Strep Mutates to Sicken Infants

Washington, DC - August 18, 2015 - Group B streptococcus, a mostly benign inhabitant of healthy adults, is one of the world’s leading causes of neonatal sepsis and meningitis. A team of French investigators has now shown that such cases might occur when the microbe mutates within the infant foll... Read More

TWiP 81 letters


Allan writes:


Dear Vincent & Dickson… and Daniel,


I always enjoy listening to TWIP here in Kona, Hawaii.


Our weather today is 79ºF and clear but we have just experienced a record 25-year overnight low of 54ºF,
(FREEZING, as few of us hav... Read More

Ebola’s Lessons - How the WHO Mishandled the Crisis

In a biological sense, last year’s Ebola epidemic, which struck West Africa, spilled over into the United States and Europe, and has to date led to more than 27,000 infections and more than 11,000 deaths, was a great surprise.

Local health and political leaders did not know of the presence o... Read More

BacterioFiles 212 - Ghosts Get Good Guarding

This episode: Bacterial ghosts could make good vaccines for different things!


(9.8 MB, 10.7 minutes)


Show notes: 
Journal Paper


Read More

Permissive vaccines and viral virulence

A permissive vaccine prevents disease in the immunized host, but does not block virus infection. Would a permissive vaccine lead to the emergence of more virulent viruses?

This hypothesis is based on the notion that viruses which kill their hosts too quickly are not efficiently transmitted, a... Read More

TWiV 302: The sky is falling

The TWiVers discuss the growing Ebola virus outbreak in West Africa, and an epidemic of respiratory disease in the US caused by enterovirus D68.


Hosts: Vincent Racaniello Read More

Harmless bacteria may be helpful against meningococcal outbreaks

Nasal drops of harmless bacteria can inhibit a related bug that sometimes causes meningococcal disease, according to new findings published online in Clinical Infectious Diseases. The study--conducted among college students, a group at higher risk for this often serious illness--suggests a new a... Read More

Cells in Senescence State May Help Slow down Aging and Cancer Treatment

BOC Sciences-Senescence means a state where cells stop further development in their function but clean themselves and remove the extra substance. Scientists found that when cells go into this stage, the growth rate of tumor would slow down, which is true of aging. The finding was made on the lev... Read More

Kicking latent HIV: New strategies to reactivate reservoirs of latent infection

In cells with latent HIV infection, the virus is dormant, and such cells are therefore not attacked by the immune system or by standard antiretroviral therapy. To eradicate the virus from the human body and truly cure a patient, reservoirs of latently infected cells need to be activated and elim... Read More

Safer, with more benefits: Parents' vaccine views shifting

ANN ARBOR, Mich. -- Over the same time period that multiple outbreaks of measles and whooping cough made headlines around the country, parents' views on vaccines became more favorable, according to a new nationally-representative poll. Read More

Biologist investigates how gene-swapping bacteria evade antibiotics

A scientific peek into bacteria boudoirs is revealing how "sex" among disease-causing microbes can lead different species or strains to become resistant to antibiotic medications. Read More

Bacterial melanin can replace Non-steroidal anti-inflammatory drugs (NSAIDs) in arthritis treatments

Melanin produced by a marine bacteria Bacillus spp. has shown shown to have good anti-inflammatory activity. The pigment had shown to inhibit inflammatory enzymes cycloxygenase, lipooxygenase, myeloperoxide,NO synthase in vitro at a concentration which was non-cytotoxic..This will be a breakthro... Read More

Improved survival of HIV patients facilitates heart disease research

WASHINGTON (July 27, 2015) - The improved survival rate of HIV patients in sub-Saharan Africa due to effective treatment programs is increasing the ability of researchers in Africa to study the impacts of cardiovascular disease in HIV patients, according to a guest editor page published today in... Read More

TWiP 85 letters

 


Jan writes:


Dear Sirs


This is fun, and although I'm sure someone will gripe about Dicksons enthusiastic response to the crayfish, it made my life easier. I think it's Paragonimus kellicoti. As for eating raw crayfish; how drunk... Read More

BacterioFiles Special - ASM2015

Here's my summary of ASM2015, an exciting weekend full of science.


(11.5 MB, 12.5 minutes)


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Download Episode<... Read More

Smut, but the Safe For Work Kind, unless you work with plants....

So I told ccondayan I would post something lewd to MicrobeWorld (who probably thought I was joking). And what could be more lewd than genuine smut? Of course, since this is MicrobeWorld, I'm posting about the group of fungal plant pathogens referred to as smut. When I worked in a plant pathol... Read More

How long have primates been infected with viruses related to HIV?

Disease-causing viruses engage their hosts in ongoing arms races: positive selection for antiviral genes increases host fitness and survival, and viruses in turn select for mutations that counteract the antiviral host factors. Studying such adaptive mutations can provide insights into the distan... Read More

Malaria's key to the liver uncovered

Scientists uncover a port of liver entry for malaria parasites in a report published in The Journal of Experimental Medicine. If these results hold up in humans, drugs that target this entry protein might help prevent the spread of disease. Read More

TWiV 320: Retroviruses and cranberries

Vincent speaks with John Coffin about his career studying retroviruses, including working with Howard Temin, endogenous retroviruses, XMRV, chronic fatigue syndrome and prostate cancer, HIV/AIDS, and his interest in growing cranberries.


Host:  Read More

Some vaccines support evolution of more-virulent viruses

Scientific experiments with the herpesvirus such as the one that causes Marek's disease in poultry have confirmed, for the first time, the highly controversial theory that some vaccines could allow more-virulent versions of a virus to survive, putting unvaccinated individuals at greater risk of ... Read More
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